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公开(公告)号：US20160143978A1
公开(公告)日：2016-05-26
申请号：US14648715
申请日：2013-03-07
Applicant: Colgate-Palmolive Company
Inventor： Shashank Potnis , Ravi Subramanyam , Rajitha Nair
IPC: A61K36/61 , A61K31/045 , A61K31/125 , A61K9/06 , A61K9/00
CPC classification number: A61K36/61 , A61K9/0053 , A61K9/06 , A61K31/045 , A61K31/085 , A61K31/125 , A61K36/185 , A61K36/48 , A61K47/183 , A61K47/32 , A61K2300/00
Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.
Abstract translation: 本文公开了口服可接受的局部止痛凝胶，其包含镇痛油的混合物，其包含（a）丁香油和/或丁子香酚，（b）冷却剂和（c）樟脑，在口腔可接受的凝胶基质中，所述凝胶基质包含 阴离子聚合物和碱性氨基酸，并且镇痛凝胶与施用于牙齿的镇痛油混合物以及制备和使用止痛剂的方法一起提供控制释放。
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公开(公告)号：US09463159B2
公开(公告)日：2016-10-11
申请号：US14648868
申请日：2013-03-07
Applicant: Colgate-Palmolive Company
Inventor： Shashank Potnis , Ravi Subramanyam , Rajitha Nair
IPC: A61K36/00 , A61K9/00 , A61Q11/00 , A61K47/34 , A61K31/125 , A61K36/61 , A61K31/085 , A61K8/34 , A61K8/35 , A61K8/92 , A61K8/04
CPC classification number: A61K9/0053 , A61K8/042 , A61K8/34 , A61K8/347 , A61K8/35 , A61K8/922 , A61K31/085 , A61K31/125 , A61K36/61 , A61K47/34 , A61Q11/00 , A61K2300/00
Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; in an orally acceptable gel base, the gel base providing controlled release of the mixture of analgesic oils following application to a tooth; together with methods of making and using the same.
Abstract translation: 本文公开了口服可接受的局部止痛凝胶，其包含镇痛油的混合物，其包含（a）丁香油和/或丁子香油，（b）冷却剂和（c）樟脑; 在口服可接受的凝胶基质中，凝胶基质在施用于牙齿后提供镇痛油混合物的控制释放; 以及制作和使用方法。
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公开(公告)号：US11033594B2
公开(公告)日：2021-06-15
申请号：US14648715
申请日：2013-03-07
Applicant: Colgate-Palmolive Company
Inventor： Shashank Potnis , Ravi Subramanyam , Rajitha Nair
IPC: A61K36/61 , A61K9/00 , A61K31/125 , A61K47/18 , A61K47/32 , A61K31/085 , A61K9/06 , A61K31/045 , A61K36/48 , A61K36/185
Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.
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公开(公告)号：US20150313955A1
公开(公告)日：2015-11-05
申请号：US14648868
申请日：2013-03-07
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Shashank Potnis , Ravi Subramanyam , Rajitha Nair
IPC: A61K36/61 , A61K31/125 , A61K31/085
CPC classification number: A61K9/0053 , A61K8/042 , A61K8/34 , A61K8/347 , A61K8/35 , A61K8/922 , A61K31/085 , A61K31/125 , A61K36/61 , A61K47/34 , A61Q11/00 , A61K2300/00
Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; in an orally acceptable gel base, the gel base providing controlled release of the mixture of analgesic oils following application to a tooth; together with methods of making and using the same.
Abstract translation: 本文公开了口服可接受的局部止痛凝胶，其包含镇痛油的混合物，其包含（a）丁香油和/或丁子香油，（b）冷却剂和（c）樟脑; 在口服可接受的凝胶基质中，凝胶基质在施用于牙齿后提供镇痛油混合物的控制释放; 以及制作和使用方法。
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