公开(公告)号：US20200239540A1

公开(公告)日：2020-07-30

申请号：US16851649

申请日：2020-04-17

Applicant: CORNING INCORPORATED

Inventor： Na Li ,  Christopher Jerome Patten ,  Jie Wang

IPC: C07K14/705 ,  G05B15/02 ,  G08B13/00 ,  G08B13/196 ,  G08B25/00 ,  G08B25/08 ,  G08B29/18 ,  C12N15/85 ,  A01N1/02 ,  C12N5/00 ,  C12N5/071 ,  G01N33/50

Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.

公开(公告)号：US20200239539A1

公开(公告)日：2020-07-30

申请号：US16851634

申请日：2020-04-17

Applicant: CORNING INCORPORATED

Inventor： Na Li ,  Christopher Jerome Patten ,  Jie Wang

IPC: C07K14/705 ,  G05B15/02 ,  G08B13/00 ,  G08B13/196 ,  G08B25/00 ,  G08B25/08 ,  G08B29/18 ,  C12N15/85 ,  A01N1/02 ,  C12N5/00 ,  C12N5/071 ,  G01N33/50

Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.