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公开(公告)号:US20190263884A1
公开(公告)日:2019-08-29
申请号:US16407860
申请日:2019-05-09
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US10336806B2
公开(公告)日:2019-07-02
申请号:US15988819
申请日:2018-05-24
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US20200239540A1
公开(公告)日:2020-07-30
申请号:US16851649
申请日:2020-04-17
Applicant: CORNING INCORPORATED
Inventor: Na Li , Christopher Jerome Patten , Jie Wang
IPC: C07K14/705 , G05B15/02 , G08B13/00 , G08B13/196 , G08B25/00 , G08B25/08 , G08B29/18 , C12N15/85 , A01N1/02 , C12N5/00 , C12N5/071 , G01N33/50
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US10047136B2
公开(公告)日:2018-08-14
申请号:US15688983
申请日:2017-08-29
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US20170355745A1
公开(公告)日:2017-12-14
申请号:US15688942
申请日:2017-08-29
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
CPC classification number: C07K14/705 , A01N1/021 , A01N1/0284 , C12N5/00 , C12N5/067 , C12N5/069 , C12N15/85 , C12N2510/00 , G01N33/5008 , G01N2333/705
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US09822160B2
公开(公告)日:2017-11-21
申请号:US14972012
申请日:2015-12-16
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
CPC classification number: C07K14/705 , A01N1/021 , A01N1/0284 , C12N5/00 , C12N5/067 , C12N5/069 , C12N15/85 , C12N2510/00 , G01N33/5008 , G01N2333/705
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US20160264641A1
公开(公告)日:2016-09-15
申请号:US15163218
申请日:2016-05-24
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
IPC: C07K14/705 , G01N33/50 , C12N5/00 , A01N1/02 , C12N5/071
CPC classification number: C07K14/705 , A01N1/021 , A01N1/0284 , C12N5/00 , C12N5/067 , C12N5/069 , C12N15/85 , C12N2510/00 , G01N33/5008 , G01N2333/705
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US20190263885A1
公开(公告)日:2019-08-29
申请号:US16407943
申请日:2019-05-09
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US20180265563A1
公开(公告)日:2018-09-20
申请号:US15988819
申请日:2018-05-24
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
CPC classification number: C07K14/705 , A01N1/021 , A01N1/0284 , C12N5/00 , C12N5/067 , C12N5/069 , C12N15/85 , C12N2510/00 , G01N33/5008 , G01N2333/705
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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公开(公告)号:US10336805B2
公开(公告)日:2019-07-02
申请号:US15988802
申请日:2018-05-24
Applicant: Corning Incorporated
Inventor: Na Li , Jie Wang , Christopher J. Patten
Abstract: The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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