STABLE BIOACTIVE GLASS FORMULATIONS

    公开(公告)号:US20240366482A1

    公开(公告)日:2024-11-07

    申请号:US18642098

    申请日:2024-04-22

    Abstract: An aqueous dentifrice formulation, comprising: a bioactive glass exhibiting at least one of: a hydrolytic resistance of glass grains (HGB) of at most 4, when measured by International Organization for Standardization section 719 (ISO 719); a weight loss of 5 wt. % or less after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; an XRD spectrum substantially free of crystalline phase after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; or any combination thereof; wherein, when the bioactive glass is contacted with artificial saliva, the bioactive glass forms a bioactive crystalline phase. A method of using the aqueous dentifrice formulation to remineralize enamel of the tooth, treat caries of the tooth, treat dentin hypersensitivity of the tooth, or any combination thereof.

    BIOACTIVE GLASS COMPOSITIONS
    5.
    发明申请

    公开(公告)号:US20220274866A1

    公开(公告)日:2022-09-01

    申请号:US17186044

    申请日:2021-02-26

    Abstract: A silicate-based glass composition includes 15-65 wt. % SiO2, 2.5-25 wt. % MgO, 1-30 wt. % P2O5, and 15-50 wt. % CaO. The glass composition may also include 0-5 wt. % F−, and 0-10 wt. % ZrO2. The glass composition may also include one of 0-10 wt. % Al2O3, 0-10 wt. % SrO, and 0-10 wt. % ZnO.

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