公开(公告)号：US12098094B2

公开(公告)日：2024-09-24

申请号：US17973065

申请日：2022-10-25

Applicant: CORNING INCORPORATED

Inventor： George Halsey Beall ,  Qiang Fu ,  Xiaoju Guo ,  Peter Joseph Lezzi ,  Zhihao Liao ,  Pascale Oram ,  Charisse Marye Spier ,  Alana Marie Whittier

IPC: B32B15/04 ,  B32B17/06 ,  C03C3/085 ,  C03C21/00

CPC classification number: C03C3/085 ,  C03C21/002 ,  C03C2204/00

Abstract: In embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 11.5 mol % to 25 mol % Al2O3; from 2 mol % to 20 mol % Li2O; from greater than 0 mol % to 10 mol % Na2O; from 9 mol % to 19 mol % MgO; from 4 mol % ZrO2; and from 0 mol % to 0.5 mol % TiO2. In other embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 4 mol % to 25 mol % Al2O3; from 5 mol % to 20 mol % Li2O; from 0.1 mol % to 10 mol % Na2O; from 6 mol % to 25 mol % MgO; from 0.1 mol % to 4 mol % ZrO2; from 0.1 mol % to 5 mol % K2O; and from 0.05 mol % to 0.5 mol % SnO2.

公开(公告)号：US20230133219A1

公开(公告)日：2023-05-04

申请号：US17980955

申请日：2022-11-04

Applicant: Corning Incorporated

Inventor： Qiang Fu ,  Aize Li ,  Charisse Marye Spier

IPC: C03C3/087

Abstract: A silicate-based glass composition includes 15-65 wt. % SiO2, 15-50 wt. % CaO, 1-30 wt. % P2O5, and 1-20 wt. % ZrO2, such that the composition has a hydrolytic resistance of glass grains (HGB) of at most 3, when measured by International Organization for Standardization section 719 (ISO 719), and forms a bioactive crystalline phase in simulated body fluid.

公开(公告)号：US20250051219A1

公开(公告)日：2025-02-13

申请号：US18797619

申请日：2024-08-08

Applicant: CORNING INCORPORATED

Inventor： Qiang Fu ,  Kayla Nicole Horton ,  Cedrick Alexander O’Shaughnessy ,  Charisse Marye Spier ,  Alana Marie Whittier

IPC: C03C3/095 ,  C03C21/00

Abstract: A glass composition includes: greater than or equal to about 70 mol % and less than or equal to about 90 mol % SiO2; greater than or equal to about 2 mol % and less than or equal to about 9 mol % Al2O3; greater than or equal to about 5 mol % and less than or equal to about 15 mol % Li2O; greater than or equal to about 0 mol % and less than or equal to about 10 mol % Y2O3; greater than or equal to about 0 mol % and less than or equal to about 9 mol % Ta2O5; greater than or equal to about 0 mol % and less than or equal to about 10 mol % La2O3; and greater than or equal to about 0.05 mol % and less than or equal to about 1 mol % SnO2. The sum of Y2O3, Ta2O5, and La2O3 may be greater than or equal to about 2 mol % and less than or equal to about 15 mol %.

公开(公告)号：US20240325263A1

公开(公告)日：2024-10-03

申请号：US18613863

申请日：2024-03-22

Applicant: CORNING INCORPORATED

Inventor： Qiang Fu ,  Charisse Marye Spier ,  Nicholas Michael Stone-Weiss

IPC: A61K8/25 ,  A61K8/19 ,  A61K8/21 ,  A61K8/28 ,  A61Q11/00

CPC classification number: A61K8/25 ,  A61K8/19 ,  A61K8/21 ,  A61K8/28 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/30

Abstract: Glass compositions comprising 15-50 wt. % SiO2, 25-60 wt. % CaO, 3-30 wt. % P2O5, 0.5-15 wt. % ZrO2, and >0-5 wt. % F, wherein, when subjected to artificial saliva, the glass composition forms a bioactive crystalline phase, such as apatite. A matrix comprising the glass composition, wherein the glass composition is attached to the matrix or mixed therein, in which the matrix includes at least one of: a toothpaste, mouthwash, gel, varnish, rinse, spray, ointment, salve, cream, bandage, polymer film, oral formulation, pill, capsule, or transdermal formulation. The matrix may be a dentifrice composition. A method comprising applying the matrix to a tooth, in which the method remineralizes enamel of the tooth, treats caries of the tooth, treats dentin hypersensitivity of the tooth, or any combination thereof.

公开(公告)号：US20240400436A1

公开(公告)日：2024-12-05

申请号：US18799044

申请日：2024-08-09

Applicant: CORNING INCORPORATED

Inventor： George Halsey Beall ,  Qiang Fu ,  Xiaoju Guo ,  Peter Joseph Lezzi ,  Zhihao Liao ,  Pascale Oram ,  Charisse Marye Spier ,  Alana Marie Whittier

IPC: C03C3/085 ,  C03C21/00

Abstract: In embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 11.5 mol % to 25 mol % Al2O3; from 2 mol % to 20 mol % Li2O; from greater than 0 mol % to 10 mol % Na2O; from 9 mol % to 19 mol % MgO; from 4 mol % ZrO2; and from 0 mol % to 0.5 mol % TiO2. In other embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 4 mol % to 25 mol % Al2O3; from 5 mol % to 20 mol % Li2O; from 0.1 mol % to 10 mol % Na2O; from 6 mol % to 25 mol % MgO; from 0.1 mol % to 4 mol % ZrO2; from 0.1 mol % to 5 mol % K2O; and from 0.05 mol % to 0.5 mol % SnO2.

公开(公告)号：US20240366482A1

公开(公告)日：2024-11-07

申请号：US18642098

申请日：2024-04-22

Applicant: CORNING INCORPORATED

Inventor： Erin Coon ,  Qiang Fu ,  Aize Li ,  Hugh Michael McMahon ,  Charisse Marye Spier ,  Nicholas Michael Stone-Weiss ,  Joanna E. Warzyszynska

IPC: A61K8/24 ,  A61K8/19 ,  A61K8/25 ,  A61Q11/00 ,  C03C3/062 ,  C03C3/097 ,  C03C3/112 ,  C03C4/00

Abstract: An aqueous dentifrice formulation, comprising: a bioactive glass exhibiting at least one of: a hydrolytic resistance of glass grains (HGB) of at most 4, when measured by International Organization for Standardization section 719 (ISO 719); a weight loss of 5 wt. % or less after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; an XRD spectrum substantially free of crystalline phase after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; or any combination thereof; wherein, when the bioactive glass is contacted with artificial saliva, the bioactive glass forms a bioactive crystalline phase. A method of using the aqueous dentifrice formulation to remineralize enamel of the tooth, treat caries of the tooth, treat dentin hypersensitivity of the tooth, or any combination thereof.

公开(公告)号：US20230143992A1

公开(公告)日：2023-05-11

申请号：US17983807

申请日：2022-11-09

Applicant: CORNING INCORPORATED

Inventor： Qiang Fu ,  Xiaoju Guo ,  Peter Joseph Lezzi ,  Charisse Marye Spier ,  Alana Marie Whittier

IPC: C03C3/097 ,  C03C21/00

CPC classification number: C03C3/097 ,  C03C21/002 ,  H05K5/0018

Abstract: A glass composition includes: greater than or equal to 56 mol % to less than or equal to 70 mol % SiO2; greater than or equal to 12 mol % to less than or equal to 20 mol % Al2O3; greater than or equal to 0 mol % to less than or equal to 4 mol % P2O5; greater than or equal to 0 mol % to less than or equal to 8 mol % B2O3; greater than or equal to 6 mol % to less than or equal to 12 mol % Li2O; greater than or equal to 4 mol % to less than or equal to 12 mol % Na2O; greater than or equal to 0.4 mol % to less than or equal to 3 mol % K2O; greater than or equal to 2 mol % to less than or equal to 6 mol % MgO; greater than or equal to 0.25 mol % to less than or equal to 6 mol % CaO; greater than or equal to 0 mol % to less than or equal to 3 mol % SrO; greater than or equal to 0 mol % to less than or equal to 5 mol % ZnO; and greater than or equal to 0 mol % to less than or equal to 1 mol % ZrO2. The glass composition may have a fracture toughness of greater than or equal 0.75 MPa·m0.5 and a Young's modulus of greater than or equal to 80 GPa. The glass composition is chemically strengthenable. The glass composition may be used in a glass-based article or a consumer electronic product.

公开(公告)号：US20230129031A1

公开(公告)日：2023-04-27

申请号：US17973065

申请日：2022-10-25

Applicant: CORNING INCORPORATED

Inventor： George Halsey Beall ,  Qiang Fu ,  Xiaoju Guo ,  Peter Joseph Lezzi ,  Zhihao Liao ,  Pascale Oram ,  Charisse Marye Spier ,  Alana Marie Whittier

IPC: C03C3/085 ,  C03C21/00

Abstract: In embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 11.5 mol % to 25 mol % Al2O3; from 2 mol % to 20 mol % Li2O; from greater than 0 mol % to 10 mol % Na2O; from 9 mol % to 19 mol % MgO; from 4 mol % ZrO2; and from 0 mol % to 0.5 mol % TiO2. In other embodiments, a glass includes from 45 mol % to 70 mol % SiO2; from 4 mol % to 25 mol % Al2O3; from 5 mol % to 20 mol % Li2O; from 0.1 mol % to 10 mol % Na2O; from 6 mol % to 25 mol % MgO; from 0.1 mol % to 4 mol % ZrO2; from 0.1 mol % to 5 mol % K2O; and from 0.05 mol % to 0.5 mol % SnO2.