公开(公告)号：US09744037B2

公开(公告)日：2017-08-29

申请号：US14212860

申请日：2014-03-14

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Arash Kheradvar ,  Gregory S. Kelley ,  Morteza Gharib

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2220/0033 ,  A61F2250/0006

Abstract: Improved catheter devices for delivery, repositioning and/or percutaneous retrieval of percutaneously implanted heart valves are described, including a medical device handle that provides an array of features helpful in conducting a percutaneous heart valve implantation procedure while variously enabling radial expansion or contraction and/or lateral positioning control over the heart valve during the medical procedure.

公开(公告)号：US20130310923A1

公开(公告)日：2013-11-21

申请号：US13862302

申请日：2013-04-12

Applicant: OF THE UNIVERSITY OF CALIFORNIA ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Arash Kheradvar ,  Gregory Kelly ,  Morteza Gharib

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/12 ,  A61B90/37 ,  A61B2090/3782 ,  A61F2/2427

Abstract: Embodiments described herein address the need for improved catheter devices for delivery, repositioning and/or percutaneous retrieval of the percutaneously implanted heart valves. One embodiment employs a plurality of spring-loaded arms releasably engaged with a stent frame for controlling expansion for valve deployment. Another embodiment employs a plurality of filaments passing through a distal end of a pusher sleeve and apertures in a self-expandable stent frame to control its state of deployment. With additional features, lateral positioning of the stent frame may also be controlled. Yet another embodiment includes plurality of outwardly biased arms held to complimentary stent frame features by overlying sheath segments. Still another embodiment integrates a visualization system in the subject delivery system. Variations on hardware and methods associated with the use of these embodiments are contemplated in addition to those shown and described.

Abstract translation: 本文描述的实施例解决了对用于经皮植入的心脏瓣膜的输送，重新定位和/或经皮取出的改进的导管装置的需要。 一个实施例采用可释放地与支架框架接合的多个弹簧加载臂，用于控制阀部署的膨胀。 另一个实施例采用多个细丝穿过推进套筒的远端和自扩张支架框架中的孔，以控制其展开状态。 通过附加特征，还可以控制支架框架的横向定位。 又一个实施例包括多个向外偏置的臂，通过覆盖护套段保持到互补的支架框架特征。 另一个实施例将可视化系统集成在主体传送系统中。 除了显示和描述的之外，还考虑了与使用这些实施例相关联的硬件和方法的变化。

公开(公告)号：US20140100651A1

公开(公告)日：2014-04-10

申请号：US13773389

申请日：2013-02-21

Applicant: California Institute of Technology

Inventor： Arash Kheradvar ,  Jimmy L. Su ,  Ahmad Falahatpisheh ,  Morteza Gharib

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61B17/0643 ,  A61B2017/0647 ,  A61F2/24 ,  A61F2/2418 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054

Abstract: Connecting mechanisms between medical device or other physical components are described. One or more plug pin connector(s) is received in a matching socket connector(s) to either permanently or temporarily join at least two components together along with associated components. Each plug connector is associated with a releasable pull line to facilitate such assembly.

Abstract translation: 描述医疗设备或其他物理组件之间的连接机制。 一个或多个插头销连接器被接收在匹配的插座连接器中，以将永久地或暂时地连接至少两个部件以及相关联的部件。 每个插头连接器与可释放的拉线相关联以便于这种组装。

公开(公告)号：US09668859B2

公开(公告)日：2017-06-06

申请号：US13862302

申请日：2013-04-12

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Arash Kheradvar ,  Gregory S. Kelley ,  Morteza Gharib

IPC: A61F2/24 ,  A61B8/12 ,  A61B8/08 ,  A61B90/00

CPC classification number: A61F2/2439 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/12 ,  A61B90/37 ,  A61B2090/3782 ,  A61F2/2427

Abstract: Embodiments described herein address the need for improved catheter devices for delivery, repositioning and/or percutaneous retrieval of the percutaneously implanted heart valves. One embodiment employs a plurality of spring-loaded arms releasably engaged with a stent frame for controlling expansion for valve deployment. Another embodiment employs a plurality of filaments passing through a distal end of a pusher sleeve and apertures in a self-expandable stent frame to control its state of deployment. With additional features, lateral positioning of the stent frame may also be controlled. Yet another embodiment includes plurality of outwardly biased arms held to complimentary stent frame features by overlying sheath segments. Still another embodiment integrates a visualization system in the subject delivery system. Variations on hardware and methods associated with the use of these embodiments are contemplated in addition to those shown and described.