公开(公告)号：US20180118706A1

公开(公告)日：2018-05-03

申请号：US15848686

申请日：2017-12-20

Applicant: California Institute of Technology

Inventor： Sarah Reisman ,  Kangway V. Chuang ,  Chen Xu

IPC: C07D309/30 ,  C07C49/753 ,  C07D309/32 ,  C07C43/23 ,  C07C49/743 ,  C07C49/577 ,  C07C43/315

CPC classification number: C07D309/30 ,  C07C43/23 ,  C07C43/315 ,  C07C49/577 ,  C07C49/743 ,  C07C49/753 ,  C07D309/32

Abstract: This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogues thereof and novel compounds prepared thereby.

公开(公告)号：US20170174648A1

公开(公告)日：2017-06-22

申请号：US15381595

申请日：2016-12-16

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Sarah Reisman ,  Kangway V. Chuang ,  Chen Xu

IPC: C07D309/30 ,  C07D309/32 ,  C07C49/577 ,  C07C49/753 ,  C07C43/23

CPC classification number: C07D309/30 ,  C07C43/23 ,  C07C43/315 ,  C07C49/577 ,  C07C49/743 ,  C07C49/753 ,  C07D309/32

Abstract: This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogues thereof and novel compounds prepared thereby.

公开(公告)号：US10995049B2

公开(公告)日：2021-05-04

申请号：US16922290

申请日：2020-07-07

Applicant: California Institute of Technology

Inventor： Jiaming Li ,  Chen Xu ,  Tonia S Ahmed ,  Robert H Grubbs ,  Brian M. Stoltz

IPC: C07C45/29 ,  C07C29/00 ,  C07C49/557 ,  C07C49/577

Abstract: The present disclosure is directed to methods of preparing prostaglandin J natural products by stereoretentive metatheses reactions and intermediates used in the synthesis of these natural products, including the use of intermediates of Formula (I-A), where R1 is defined in the specification

公开(公告)号：US20210017111A1

公开(公告)日：2021-01-21

申请号：US16922290

申请日：2020-07-07

Applicant: California Institute of Technology

Inventor： Jiaming Li ,  Chen Xu ,  Tonia S. Ahmed ,  Robert H. Grubbs ,  Brian M. Stoltz

IPC: C07C45/29 ,  C07C49/577 ,  C07C49/557

Abstract: The present disclosure is directed to methods of preparing prostaglandin J natural products by stereoretentive metatheses reactions and intermediates used in the synthesis of these natural products, including the use of intermediates of Formula (I-A), where R1 is defined in the specification

公开(公告)号：US10392360B2

公开(公告)日：2019-08-27

申请号：US15848686

申请日：2017-12-20

Applicant: California Institute of Technology

Inventor： Sarah Reisman ,  Kangway V. Chuang ,  Chen Xu

IPC: C07D309/00 ,  C07D309/30 ,  C07C43/23 ,  C07C49/577 ,  C07C49/753 ,  C07D309/32 ,  C07C43/315 ,  C07C49/743

Abstract: This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogs thereof and novel compounds prepared thereby.

公开(公告)号：US09862696B2

公开(公告)日：2018-01-09

申请号：US15381595

申请日：2016-12-16

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Sarah Reisman ,  Kangway V. Chuang ,  Chen Xu

IPC: C07D309/30 ,  C07C43/23 ,  C07C49/577 ,  C07C49/753 ,  C07D309/32 ,  C07C43/315 ,  C07C49/743

CPC classification number: C07D309/30 ,  C07C43/23 ,  C07C43/315 ,  C07C49/577 ,  C07C49/743 ,  C07C49/753 ,  C07D309/32

Abstract: This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogs thereof and novel compounds prepared thereby.