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1.发明申请公开(公告)号：US20060193854A1
公开(公告)日：2006-08-31
申请号：US11429361
申请日：2006-05-05
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K39/395 , A61K31/525 , A61K31/7072 , A61K31/282 , A61K31/337 , A61K33/24
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes humanized anti-ErbB2 antibodies and methods for treating cancer with anti-ErbB2 antibodies, such as humanized anti-ErbB2 antibodies.
摘要翻译： 本申请描述了人源化抗ErbB2抗体和用抗ErbB2抗体如人源化抗ErbB2抗体治疗癌症的方法。
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公开(公告)号：US20060198843A1
公开(公告)日：2006-09-07
申请号：US11429043
申请日：2006-05-05
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K39/395 , A61K31/7072 , A61K31/337 , A61K31/282 , A61K33/24
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes methods for treating cancer with anti-ErbB2 antibodies, such as humanized anti-ErbB2 antibodies, and chemotherapeutic agents.
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公开(公告)号：US20060073143A1
公开(公告)日：2006-04-06
申请号：US11222587
申请日：2005-09-09
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K39/395
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes methods for treating cancer with anti-ErbB2 antibodies, such as humanized anti-ErbB2 antibodies, and anti-hormonal compounds, such as anti-estrogens.
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公开(公告)号：US20060034842A1
公开(公告)日：2006-02-16
申请号：US11223361
申请日：2005-09-09
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K39/395
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes methods for treating ErbB-expressing cancer with anti-ErbB2 antibody combinations.
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公开(公告)号：US20060216285A1
公开(公告)日：2006-09-28
申请号：US11429363
申请日：2006-05-05
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K39/395
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes humanized anti-ErbB2 antibodies and methods for treating cancer with anti-ErbB2 antibodies, such as humanized anti-ErbB2 antibodies.
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公开(公告)号：US20050208043A1
公开(公告)日：2005-09-22
申请号：US11044749
申请日：2005-01-27
申请人： Camellia Adams , Leonard Presta , Mark Sliwkowski
发明人： Camellia Adams , Leonard Presta , Mark Sliwkowski
IPC分类号： A61K47/48 , C07K16/32 , A61K39/395 , C07K16/44
CPC分类号： A61K31/282 , A61K31/337 , A61K31/525 , A61K31/7072 , A61K33/24 , A61K39/395 , A61K45/06 , A61K47/6809 , A61K2039/505 , C07K16/32 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S424/80 , Y10S424/801 , A61K2300/00
摘要： The present application describes humanized anti-ErbB2 antibodies and methods for treating cancer with anti-ErbB2 antibodies, such as humanized anti-ErbB2 antibodies.
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公开(公告)号：US20060034835A1
公开(公告)日：2006-02-16
申请号：US11147780
申请日：2005-06-07
申请人： Camellia Adams , Andrew Chan , Craig Crowley , Henry Lowman , Gerald Nakamura , Leonard Presta
发明人： Camellia Adams , Andrew Chan , Craig Crowley , Henry Lowman , Gerald Nakamura , Leonard Presta
IPC分类号： A61K39/395 , C07K16/44
CPC分类号： C07K16/2887 , A61K2039/505 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/72 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/75 , C07K2317/92
摘要： The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.
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公开(公告)号：US20060024300A1
公开(公告)日：2006-02-02
申请号：US11190364
申请日：2005-07-26
申请人： Camellia Adams , Andrew Chan , Craig Crowley , Henry Lowman , Gerald Nakamura , Leonard Presta
发明人： Camellia Adams , Andrew Chan , Craig Crowley , Henry Lowman , Gerald Nakamura , Leonard Presta
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2887 , A61K2039/505 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/72 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/75 , C07K2317/92
摘要： The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.
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公开(公告)号：US20050276802A1
公开(公告)日：2005-12-15
申请号：US11096046
申请日：2005-03-31
申请人： Camellia Adams , Napoleone Ferrara , Ellen Filvaroff , Weiguang Mao , Leonard Presta , Max Tejada
发明人： Camellia Adams , Napoleone Ferrara , Ellen Filvaroff , Weiguang Mao , Leonard Presta , Max Tejada
IPC分类号： A61K39/395 , C07H21/04 , C07K16/22 , C07K16/28 , C12N5/06
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/73 , C07K2317/76 , Y10S435/81
摘要： Humanized anti-TGF-beta antibodies are provided, as well as methods for their preparation and use, including methods for treating TGF-beta disorders, for example, cancer. Also provided are articles of manufacture designed for various uses that contain the humanized antibodies.
摘要翻译： 提供人源化抗TGF-β抗体，以及其制备和使用方法，包括治疗TGF-β病症例如癌症的方法。 还提供了针对包含人源化抗体的各种用途设计的制品。
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公开(公告)号：US20060177441A1
公开(公告)日：2006-08-10
申请号：US11402010
申请日：2006-04-12
申请人： Camellia Adams , Austin Gurney
发明人： Camellia Adams , Austin Gurney
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/24 , A61K2039/505 , C07K16/2866 , C07K16/40 , C07K2317/21 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/92
摘要： Various forms of c-mpl agonist antibodies are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.
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