-
公开(公告)号：US20080114579A1
公开(公告)日：2008-05-15
申请号：US12008760
申请日：2008-01-14
IPC分类号： G06G7/60
CPC分类号： G06F19/3437 , A61B90/37 , A61B2090/364 , A61N1/0534 , A61N1/0539 , A61N1/36082 , A61N1/36135 , A61N1/36146 , G06F19/00 , G06F19/321 , G16H50/50
摘要： This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence. In another example, a neuron or axon model is used to calculate the volume of influence without computing the second difference of the electric potential distribution.
摘要翻译： 本文件还讨论了脑刺激模型，系统，设备和方法，例如深部脑刺激（DBS）或其他电刺激。 模型使用某些刺激参数（如幅度，脉冲宽度，频率，脉冲形态，电极接触选择或位置，返回路径电极选择，脉冲极性等）来计算模拟电刺激的影响区域的体积。该模型使用非 - 组织电导率不均匀。 这准确地表示脑组织，其具有产生非均匀和各向异性的组织培养基的高度定向导电的神经元途径。 在一个示例中，从扩散张量成像（DTI）数据获得非均匀组织电导率。 在一个示例中，电位分布的第二差异用于定义激活量（VOA）或类似的影响体积。 在另一个例子中，使用神经元或轴突模型来计算影响的体积，而不计算电势分布的第二差异。
-
公开(公告)号：US20080114233A1
公开(公告)日：2008-05-15
申请号：US12008764
申请日：2008-01-14
CPC分类号： G06F19/3437 , A61B90/37 , A61B2090/364 , A61N1/0534 , A61N1/0539 , A61N1/36082 , A61N1/36135 , A61N1/36146 , G06F19/00 , G06F19/321 , G16H50/50
摘要： This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence. In another example, a neuron or axon model is used to calculate the volume of influence without computing the second difference of the electric potential distribution.
摘要翻译： 本文件还讨论了脑刺激模型，系统，设备和方法，例如深部脑刺激（DBS）或其他电刺激。 模型使用某些刺激参数（如幅度，脉冲宽度，频率，脉冲形态，电极接触选择或位置，返回路径电极选择，脉冲极性等）来计算模拟电刺激的影响区域的体积。该模型使用非 - 组织电导率不均匀。 这准确地表示脑组织，其具有产生非均匀和各向异性的组织培养基的高度定向导电的神经元途径。 在一个示例中，从扩散张量成像（DTI）数据获得非均匀组织电导率。 在一个示例中，电位分布的第二差异用于定义激活量（VOA）或类似的影响体积。 在另一个例子中，使用神经元或轴突模型来计算影响的体积，而不计算电势分布的第二差异。
-
公开(公告)号：US20060017749A1
公开(公告)日：2006-01-26
申请号：US10885982
申请日：2004-07-07
IPC分类号： G09G5/00
CPC分类号： G06F19/3437 , A61B90/37 , A61B2090/364 , A61N1/0534 , A61N1/0539 , A61N1/36082 , A61N1/36135 , A61N1/36146 , G06F19/00 , G06F19/321 , G16H50/50
摘要： This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence. In another example, a neuron or axon model is used to calculate the volume of influence without computing the second difference of the electric potential distribution.
摘要翻译： 本文件还讨论了脑刺激模型，系统，设备和方法，例如深部脑刺激（DBS）或其他电刺激。 模型使用某些刺激参数（如幅度，脉冲宽度，频率，脉冲形态，电极接触选择或位置，返回路径电极选择，脉冲极性等）来计算模拟电刺激的影响区域的体积。该模型使用非 - 组织电导率不均匀。 这准确地表示脑组织，其具有产生非均匀和各向异性的组织培养基的高度定向导电的神经元途径。 在一个示例中，从扩散张量成像（DTI）数据获得非均匀组织电导率。 在一个示例中，电位分布的第二差异用于定义激活量（VOA）或类似的影响体积。 在另一个例子中，使用神经元或轴突模型来计算影响的体积，而不计算电势分布的第二差异。
-
4.发明申请System and method to design structure for delivering electrical energy to tissue 有权设计将电能传递给组织的结构的系统和方法公开(公告)号：US20070083104A1
公开(公告)日：2007-04-12
申请号：US11606260
申请日：2006-11-28
IPC分类号： A61B5/05
CPC分类号： A61N1/0534 , A61N1/08
摘要： A computer-assisted method can include defining a target volume of tissue activation to achieve a desired therapeutic effect for an identified anatomic region. At least one parameter can be computed for an electrode design as a function of the defined target volume of tissue activation. The computed at least one parameter can be stored in memory for the electrode design, which parameter can be utilized to construct an electrode.
摘要翻译： 计算机辅助方法可以包括限定组织活化的目标体积以实现对所识别的解剖区域的期望的治疗效果。 对于电极设计可以计算至少一个参数，作为组织激活的定义的目标体积的函数。 计算的至少一个参数可以存储在用于电极设计的存储器中，该参数可以用于构建电极。
-
5.发明申请Systems and methods for determining volume of activation for deep brain stimulation 有权用于确定深部脑刺激活化体积的系统和方法公开(公告)号：US20070288064A1
公开(公告)日：2007-12-13
申请号：US11715829
申请日：2007-03-08
IPC分类号： A61N1/05
CPC分类号： A61B5/7257 , A61B5/053 , A61B5/0538 , A61B5/4064 , A61B5/7217 , A61N1/0534 , G06F17/5018 , G06F19/00 , G06F2217/78 , G16H50/50
摘要： This document discusses, among other things, systems and methods for determining volume of activation for deep brain stimulation (“DBS”) using a finite element model (FEM) circuit to determine a FEM of an implanted electrode and a tissue medium in which the electrode is implanted, a Fourier FEM solver circuit to calculate a potential distribution in the tissue medium using information from the FEM circuit and a capacitive component of at least one of the implanted electrode and the tissue medium, and a volume of activation (VOA) circuit to predict a VOA using the potential distribution and a neuron model.
摘要翻译： 本文件尤其讨论了使用有限元模型（FEM）电路确定深部脑刺激（“DBS”）激活体积的系统和方法，以确定植入电极和组织介质的FEM，其中电极 植入的傅里叶FEM解算器电路，使用来自FEM电路的信息和至少一个注入电极和组织介质的电容分量以及一定量的激活（VOA）电路来计算组织介质中的电位分布， 使用潜在分布和神经元模型预测VOA。
-
公开(公告)号：US20130218819A1
公开(公告)日：2013-08-22
申请号：US13839906
申请日：2013-03-15
CPC分类号： G06N20/00 , A61N1/0534 , A61N1/36082 , A61N1/36185 , G06F19/3481 , G06K9/6256 , G06K9/6269 , G06N5/025 , G06N7/005 , G16H50/50
摘要： A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
摘要翻译： 用于确定神经组织的活化体积的计算机实现的方法。 在一个实施例中，该方法使用定义激活体积的一个或多个参数方程，其中一个或多个参数方程的参数作为包括刺激参数的输入向量的函数给出。 在接收到包含刺激参数值的输入数据并使用输入数据定义输入向量之后，将输入向量应用于函数以获得一个或多个参数方程的参数。 解决参数方程以获得计算的激活体积。
-
公开(公告)号：US10360511B2
公开(公告)日：2019-07-23
申请号：US13839906
申请日：2013-03-15
IPC分类号： G06F15/18 , G06N20/00 , A61N1/36 , G16H50/50 , G06K9/62 , G06N5/02 , G06N7/00 , A61N1/05 , G06F19/00
摘要： A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
-
8.发明授权System and method to design structure for delivering electrical energy to tissue 有权设计将电能传递给组织的结构的系统和方法公开(公告)号：US08209027B2
公开(公告)日：2012-06-26
申请号：US11606260
申请日：2006-11-28
CPC分类号： A61N1/0534 , A61N1/08
摘要： A computer-assisted method can include defining a target volume of tissue activation to achieve a desired therapeutic effect for an identified anatomic region. At least one parameter can be computed for an electrode design as a function of the defined target volume of tissue activation. The computed at least one parameter can be stored in memory for the electrode design, which parameter can be utilized to construct an electrode.
摘要翻译： 计算机辅助方法可以包括限定组织活化的目标体积以实现对所识别的解剖区域的期望的治疗效果。 对于电极设计可以计算至少一个参数，作为组织激活的定义的目标体积的函数。 计算的至少一个参数可以存储在用于电极设计的存储器中，该参数可以用于构建电极。
-
公开(公告)号：US20060025841A1
公开(公告)日：2006-02-02
申请号：US11191867
申请日：2005-07-27
申请人： Cameron McIntyre
发明人： Cameron McIntyre
IPC分类号： A61N1/05
CPC分类号： A61N1/0534 , A61N1/3605
摘要： The present invention provides an electrical lead configured for stimulation of the thalamus. The electrical lead provides for preferential stimulation of the medial or lateral thalamus as well as specific nuclei within the thalamus, such as the intralaminar nuclei.
摘要翻译： 本发明提供一种被配置为刺激丘脑的电引线。 电导线优先刺激内侧或外侧丘脑以及丘脑内的特定核，如内膜核。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.027 秒)
