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公开(公告)号:US20200009381A1
公开(公告)日:2020-01-09
申请号:US16512248
申请日:2019-07-15
发明人: Daniel Walter Kaiser
摘要: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.
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公开(公告)号:US20220096844A1
公开(公告)日:2022-03-31
申请号:US17493609
申请日:2021-10-04
IPC分类号: A61N1/365 , A61N1/39 , A61N1/372 , A61B5/0215 , A61B5/145 , A61B5/1459 , A61B5/283
摘要: Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.
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公开(公告)号:US10987058B2
公开(公告)日:2021-04-27
申请号:US16042892
申请日:2018-07-23
发明人: Daniel Walter Kaiser
IPC分类号: A61B5/00 , A61N1/365 , A61B5/02 , A61B5/029 , A61B5/026 , A61B5/0205 , A61B5/042 , A61B5/0215 , A61N1/05 , A61M25/00
摘要: Systems and methods are provided for optimizing hemodynamics within a patient. Specifically, the system incorporates invasive sensor data (e.g., pressure measurements) combined with mechanisms to dynamically change the loading conditions of the heart and/or heart rate, in order to understand hemodynamic parameters. Computational analyses on dynamic sensor data are used to understand and guide heart rate, filling pressures, and/or volume resuscitation in critically ill patients. By pacing the heart or inducing tricuspid regurgitation, the system may cause dynamic changes in sensor data to understand optimal loading conditions and heart rates. While determining optimal hemodynamic parameters, the system may then automatically optimize the heart rate and/or filling pressures in critically ill patients.
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公开(公告)号:US10195441B2
公开(公告)日:2019-02-05
申请号:US15168204
申请日:2016-05-30
IPC分类号: A61N1/362 , A61N1/365 , A61N1/39 , A61N1/372 , A61B5/0215 , A61B5/042 , A61B5/145 , A61B5/1459 , A61B17/00 , A61M1/12
摘要: Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.
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5.
公开(公告)号:US12121731B2
公开(公告)日:2024-10-22
申请号:US17372487
申请日:2021-07-11
IPC分类号: A61N1/36 , A61M60/135 , A61M60/148 , A61M60/295 , A61M60/414 , A61M60/497 , A61M60/531 , A61M60/841 , A61N1/362 , A61N1/365 , A61M25/10
CPC分类号: A61N1/3627 , A61M60/135 , A61M60/148 , A61M60/295 , A61M60/414 , A61M60/497 , A61M60/531 , A61M60/841 , A61N1/36521 , A61N1/36564 , A61M25/10
摘要: Apparatus, systems, and methods are provided for optimizing intracardiac filling pressures and cardiac output in patients with heart failure, conduction disease, and atrial fibrillation. The system is able to adjust and optimize intracardiac filling pressures and cardiac output by adjusting heart rate and the effective amount of total body blood volume. The device includes an adjustable member that may create a mean pressure differential in order to manifest an effective “mechanical diuresis” by sequestering extraneous blood volume to the high-capacitance of the venous vasculature. The system is therefore designed to reduce intracardiac filling pressures while maintaining or even increasing cardiac output.
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6.
公开(公告)号:US20220001163A1
公开(公告)日:2022-01-06
申请号:US17372487
申请日:2021-07-11
IPC分类号: A61M60/17 , A61N1/362 , A61N1/365 , A61M60/148 , A61M60/205 , A61M60/414
摘要: Apparatus, systems, and methods are provided for optimizing intracardiac filling pressures and cardiac output in patients with heart failure, conduction disease, and atrial fibrillation. The system is able to adjust and optimize intracardiac filling pressures and cardiac output by adjusting heart rate and the effective amount of total body blood volume. The device includes an adjustable member that may create a mean pressure differential in order to manifest an effective “mechanical diuresis” by sequestering extraneous blood volume to the high-capacitance of the venous vasculature. The system is therefore designed to reduce intracardiac filling pressures while maintaining or even increasing cardiac output.
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公开(公告)号:US20180117325A1
公开(公告)日:2018-05-03
申请号:US15791043
申请日:2017-10-23
发明人: Daniel Walter Kaiser
IPC分类号: A61N1/362 , A61N1/365 , A61B5/0464 , A61B5/00
CPC分类号: A61N1/3622 , A61B5/0464 , A61B5/7282 , A61N1/36514
摘要: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.
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8.
公开(公告)号:US20160030743A1
公开(公告)日:2016-02-04
申请号:US14811719
申请日:2015-07-28
发明人: Daniel Walter Kaiser
CPC分类号: A61N1/3622 , A61B5/0464 , A61B5/7282 , A61N1/36514
摘要: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyses, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.
摘要翻译: 提供了用于预防和/或修复心律失常的装置,系统和方法,例如, 优化抗心动过速起搏(ATP)算法。 更具体地,提供了可测量和治疗心律失常的可植入装置。 通过监测来自附加电极的ATP尝试,远场形态分析和/或测量从失败的ATP尝试的返回间隔; 装置可以估计何时发生夹带,折返性心动过速中的延迟量和/或心动过速终止/加速。 这些变量和事件可用于优化第一次和/或其后的ATP尝试。 此外,其他示例性实施例描述了将电恢复特性整合到ATP起搏算法的设计中以促进心动过速终止的方法。
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9.
公开(公告)号:US20190269928A1
公开(公告)日:2019-09-05
申请号:US16267247
申请日:2019-02-04
IPC分类号: A61N1/365 , A61N1/39 , A61N1/372 , A61B5/0215 , A61B5/145 , A61B5/1459 , A61B5/042
摘要: Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.
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公开(公告)号:US10350415B2
公开(公告)日:2019-07-16
申请号:US15791043
申请日:2017-10-23
发明人: Daniel Walter Kaiser
IPC分类号: A61B5/00 , A61N1/365 , A61B5/0464 , A61N1/362
摘要: Apparatus, systems and methods are provided for prevention and/or remediation of cardiac arrhythmias, e.g. optimizing anti-tachycardia pacing (ATP) algorithms. More particularly, implantable devices are provided that measure and treat cardiac arrhythmias. By monitoring the ATP attempt from additional electrodes, far-field morphology analyzes, and/or measuring the return interval from a failed ATP attempt; the devices may estimate when entrainment has occurred, the amount of delay within the reentrant tachycardia, and/or tachycardia termination/acceleration. These variables and occurrences can be used to optimize the first and/or subsequent ATP attempts. Furthermore, other exemplary embodiments describe methods to integrate electrical restitution properties into the design of ATP pacing algorithms to facilitate tachycardia termination.
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