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公开(公告)号:US20060035304A1
公开(公告)日:2006-02-16
申请号:US11157478
申请日:2005-06-20
申请人: Carlito Lebrilla , Hyun An , Kit Lam , Suzanne Miyamoto
发明人: Carlito Lebrilla , Hyun An , Kit Lam , Suzanne Miyamoto
IPC分类号: C12Q1/34
CPC分类号: G01N33/57415 , G01N33/57449 , G01N33/66 , Y10S607/901
摘要: The present invention provides methods for identifying oligosaccharides specific to cancer and methods for determining a strain of cancer in an individual. The present invention also provides methods for diagnosing cancer or a stage of cancer in an individual by detecting the presence or absence of specific cancer markers and methods for treating cancer by administering antibodies directed to such markers. In addition, the present invention provides cancer markers comprising O-linked oligosaccharides and kits for diagnosing or treating cancer.
摘要翻译: 本发明提供用于鉴定癌症特异性的寡糖的方法和用于确定个体中癌症菌株的方法。 本发明还提供了通过检测针对这种标记的抗体来检测特异性癌症标志物的存在或不存在以及用于治疗癌症的方法来诊断个体癌症或癌症阶段的方法。 此外,本发明提供包含O-连接的寡糖的癌症标志物和用于诊断或治疗癌症的试剂盒。
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公开(公告)号:US20050042695A1
公开(公告)日:2005-02-24
申请号:US10854735
申请日:2004-05-24
申请人: Claude Meares , Carlito Lebrilla , Nathaniel Butlin , Sarah Cheal , Todd Corneillie , Susan Lee , Paul Whetstone , Nicolas Young
发明人: Claude Meares , Carlito Lebrilla , Nathaniel Butlin , Sarah Cheal , Todd Corneillie , Susan Lee , Paul Whetstone , Nicolas Young
CPC分类号: G01N33/582 , C12Q1/6886 , G01N2458/40 , Y10S435/81 , Y10S435/973 , Y10S435/975 , Y10T436/145555 , Y10T436/24
摘要: The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules. More particularly, the invention provides Element Coded Affinity Tags comprising a metal chelate and a metal ion and methods of using the tags to detect, analyze, and identify biomolecules including polypeptides, nucleic acids, lipids, and polysaccharides.
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公开(公告)号:US08425930B2
公开(公告)日:2013-04-23
申请号:US12722813
申请日:2010-03-12
申请人: Mariana Barboza , J. Bruce German , Carlito Lebrilla , David Mills , Samara Freeman , William Robert King
发明人: Mariana Barboza , J. Bruce German , Carlito Lebrilla , David Mills , Samara Freeman , William Robert King
CPC分类号: A61K31/702 , A23L5/00 , A23L7/00 , A23L29/30 , A23L33/125 , A23L33/135 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K9/0095 , A61K35/745 , A61K38/47 , A61K2035/115 , C12Y302/01108 , A23V2250/28 , A23V2200/3204 , A23V2200/3202 , A23V2200/32
摘要: The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
摘要翻译: 本发明提供优选刺激特异性双歧杆菌物种和亚种生长的半乳寡聚糖组合物。
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公开(公告)号:US20100254949A1
公开(公告)日:2010-10-07
申请号:US12722813
申请日:2010-03-12
申请人: Mariana Barboza , J. Bruce German , Carlito Lebrilla , David Mills , Samara Freeman , William Robert King
发明人: Mariana Barboza , J. Bruce German , Carlito Lebrilla , David Mills , Samara Freeman , William Robert King
CPC分类号: A61K31/702 , A23L5/00 , A23L7/00 , A23L29/30 , A23L33/125 , A23L33/135 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K9/0095 , A61K35/745 , A61K38/47 , A61K2035/115 , C12Y302/01108 , A23V2250/28 , A23V2200/3204 , A23V2200/3202 , A23V2200/32
摘要: The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
摘要翻译: 本发明提供优选刺激特异性双歧杆菌物种和亚种生长的半乳寡聚糖组合物。
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