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公开(公告)号：US08592434B2
公开(公告)日：2013-11-26
申请号：US12634225
申请日：2009-12-09
IPC分类号： A01N43/90 , A01N43/42 , A61K31/522 , A61K31/44
CPC分类号： A61K31/522 , A61K9/006 , A61K9/2054
摘要： The present invention relates to the treatment or prevention of mucocutaneous herpes simplex virus diseases using prolonged release mucoadhesive buccal tablets comprising an acyclic guanosine antiviral agent. These tablets are particularly suitable for the treatment or prevention of orofacial herpes.
摘要翻译： 本发明涉及使用包含非循环鸟苷抗病毒剂的延长释放粘膜粘连性颊片来治疗或预防粘膜皮肤单纯疱疹病毒病。 这些片剂特别适用于治疗或预防口腔疱疹。
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公开(公告)号：US20120329817A1
公开(公告)日：2012-12-27
申请号：US13565653
申请日：2012-08-02
IPC分类号： A61K47/32 , A61P31/12 , A61K31/522 , A61K47/20 , A61K47/42
CPC分类号： A61K47/38 , A61K9/0056 , A61K9/006 , A61K9/2027 , A61K9/2063 , A61K31/4178 , A61K31/4468 , A61K31/522
摘要： A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.
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公开(公告)号：US08747896B2
公开(公告)日：2014-06-10
申请号：US13565653
申请日：2012-08-02
CPC分类号： A61K47/38 , A61K9/0056 , A61K9/006 , A61K9/2027 , A61K9/2063 , A61K31/4178 , A61K31/4468 , A61K31/522
摘要： A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.
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4.发明授权公开(公告)号：US08211466B2
公开(公告)日：2012-07-03
申请号：US12707369
申请日：2010-02-17
CPC分类号： A61K47/38 , A61K9/0056 , A61K9/006 , A61K9/2027 , A61K9/2063 , A61K31/4178 , A61K31/4468 , A61K31/522
摘要： A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.
摘要翻译： 粘膜生物粘附缓释载体，其包含活性成分并且没有淀粉，乳糖，其能够释放活性成分持续超过20小时。 该生物粘附载体包含稀释剂，碱金属烷基硫酸盐，结合剂，至少一种生物粘附聚合物和至少一种缓释聚合物，以及其制备方法。
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5.发明申请Mucosal Bioadhesive SLow Release Carrier for Delivering Active Principles 审中-公开粘膜生物粘合剂SLow释放载体提供主动原则公开(公告)号：US20090169511A1
公开(公告)日：2009-07-02
申请号：US12225470
申请日：2007-03-23
IPC分类号： A61K47/42 , A61K47/36 , A61K47/32 , A61K31/52 , A61K31/7072 , A61K31/662 , A61K31/708 , A61K31/13 , A61K38/21 , A61P31/12 , A61K47/38
CPC分类号： A61K47/38 , A61K9/0056 , A61K9/006 , A61K9/2027 , A61K9/2063 , A61K31/4178 , A61K31/4468 , A61K31/522
摘要： A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.
摘要翻译： 粘膜生物粘附缓释载体，其包含活性成分并且没有淀粉，乳糖，其能够释放活性成分持续超过20小时。 该生物粘附载体包含稀释剂，碱金属烷基硫酸盐，结合剂，至少一种生物粘附聚合物和至少一种缓释聚合物，以及其制备方法。
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6.发明申请MUCOADHESIVE BUCCAL TABLETS FOR THE TREATMENT OF OROFACIAL HERPES 审中-公开用于治疗异位睾丸的MUCOADHESIVE BUCCAL PABLETS公开(公告)号：US20130210841A1
公开(公告)日：2013-08-15
申请号：US13514594
申请日：2010-12-09
IPC分类号： A61K9/00 , A61K31/522
CPC分类号： A61K9/006 , A61K9/2054 , A61K9/2063 , A61K31/44 , A61K31/522
摘要： The present invention relates to the treatment and/or prevention of muco-cutaneous herpes simplex virus diseases using prolonged release mucoadhesive buccal tablets comprising an acyclic guanosine antiviral agent. These tablets are particularly-suitable for the treatment and/or prevention of orofacial herpes.
摘要翻译： 本发明涉及使用包含非循环鸟苷抗病毒剂的延长释放粘膜粘连性颊含药片治疗和/或预防粘膜皮肤单纯疱疹病毒病。 这些片剂特别适用于治疗和/或预防口腔疱疹。
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7.发明申请MUCOSAL BIOADHESIVE SLOW RELEASE CARRIER FOR DELIVERING ACTIVE PRINCIPLES 审中-公开MUCOSAL BIOADHESIVE SLOW RELEASE CARRIER FOR DELLERING ACTIVE PRINCIPLES公开(公告)号：US20100087454A1
公开(公告)日：2010-04-08
申请号：US12524498
申请日：2008-03-21
申请人： Caroline Lemarchand
发明人： Caroline Lemarchand
IPC分类号： A61K31/522 , A61P31/12
CPC分类号： A61K9/006 , A61K9/2063
摘要： A mucosal bioadhesive slow release carrier comprising an active principle, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains at least one bioadhesive natural protein of vegetal origin and preferably a pea protein from the genus Pisum or the species Pisum sativum, and at least one sustained release polymer, as well as a method for its preparation.
摘要翻译： 粘膜生物粘附缓释载体，其包含活性成分，其可以将活性成分释放持续超过20小时。 该生物粘附载体包含至少一种植物来源的生物粘附天然蛋白质，优选来自豌豆属豌豆或豌豆种的豌豆蛋白，以及至少一种缓释聚合物，以及其制备方法。
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8.发明申请TREATING INFLAMMATION AND INFLAMMATORY PAIN IN MUCOSA USING MUCOSAL PROLONGED RELEASE BIOADHESIVE THERAPEUTIC CARRIERS 审中-公开使用粘膜增殖释放生物治疗药物治疗粘膜炎的炎症和炎症性疼痛公开(公告)号：US20110288140A1
公开(公告)日：2011-11-24
申请号：US13119229
申请日：2009-09-17
CPC分类号： A61K31/4168 , A61K9/006 , A61K9/2009 , A61K9/2054 , A61K9/2063 , A61K9/2068 , A61K9/2095
摘要： The present invention concerns a pharmaceutical composition comprising an alpha-2 adrenergic receptor agonist for preventing or treating inflammatory pain and diseases in mucosa of oral cavity, pharynx and larynx. Inanother aspect the present invention provides mucosal bioadhesive slow release carriers for the extended and controlled release of alpha-2 adrenergic receptor agonists that can be used on mucosal surfaces for preventing or treating inflammatory pain and diseases in mucosa of oral cavity.
摘要翻译： 本发明涉及一种药物组合物，其包含用于预防或治疗炎症性疼痛和口腔，咽和喉粘膜疾病的α-2肾上腺素能受体激动剂。 另一方面，本发明提供了用于延长和控制释放α-2肾上腺素能受体激动剂的粘膜生物粘附缓释载体，其可用于粘膜表面以预防或治疗炎症性疼痛和口腔粘膜中的疾病。
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9.发明申请MUCOSAL BIOADHESIVE SLOW RELEASE CARRIER FOR DELIVERING ACTIVE PRINCIPLES 有权MUCOSAL BIOADHESIVE SLOW RELEASE CARRIER FOR DELLERING ACTIVE PRINCIPLES公开(公告)号：US20100266667A1
公开(公告)日：2010-10-21
申请号：US12707369
申请日：2010-02-17
CPC分类号： A61K47/38 , A61K9/0056 , A61K9/006 , A61K9/2027 , A61K9/2063 , A61K31/4178 , A61K31/4468 , A61K31/522
摘要： A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.
摘要翻译： 粘膜生物粘附缓释载体，其包含活性成分并且没有淀粉，乳糖，其能够释放活性成分持续超过20小时。 该生物粘附载体包含稀释剂，碱金属烷基硫酸盐，结合剂，至少一种生物粘附聚合物和至少一种缓释聚合物，以及其制备方法。
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