公开(公告)号：US07725157B2

公开(公告)日：2010-05-25

申请号：US11383608

申请日：2006-05-16

申请人： Charles Lucian Dumoulin ,  Richard Philip Mallozzi ,  Robert David Darrow ,  Harvey Ellis Cline ,  Renee Ann Guhde

发明人： Charles Lucian Dumoulin ,  Richard Philip Mallozzi ,  Robert David Darrow ,  Harvey Ellis Cline ,  Renee Ann Guhde

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/06 ,  A61B5/743 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0891 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2090/364 ,  A61B2090/374 ,  G01R33/287

摘要： An imaging and interventional system and methods are provided. The system comprises an imaging device for acquiring volumetric image data for an anatomical region of interest, a catheter for acquiring electrophysiological (EP) measurements of the anatomical region of interest, the catheter having at least one tracking coil for detecting signals indicative of a position of the catheter, and, a processor coupled to the catheter for receiving the EP measurements and signals indicative of the position of the catheter. The position of the catheter and EP measurements are combined and superimposed on a resultant image. The method comprises acquiring volumetric image data for an anatomical region of interest, acquiring position data for a catheter inserted in the region of interest, obtaining electrophysiological (EP) measurements for the region of interest and combining the image data, position data and EP measurements into a resultant image for use in the interventional procedure.

摘要翻译： 提供了成像和介入系统和方法。 该系统包括用于获取感兴趣解剖区域的体积图像数据的成像装置，用于获取感兴趣解剖区域的电生理学（EP）测量值的导管，所述导管具有至少一个跟踪线圈，用于检测指示位置的信号 导管，以及耦合到导管的处理器，用于接收EP测量值和指示导管位置的信号。 将导管的位置和EP测量结合并叠加在合成的图像上。 该方法包括获取感兴趣的解剖区域的体积图像数据，获取插入在感兴趣区域中的导管的位置数据，获得感兴趣区域的电生理（EP）测量值，并将图像数据，位置数据和EP测量结合到 用于介入程序的结果图像。

公开(公告)号：US07009396B2

公开(公告)日：2006-03-07

申请号：US10065036

申请日：2002-09-12

申请人： Yudong Zhu ,  Charles Lucian Dumoulin

发明人： Yudong Zhu ,  Charles Lucian Dumoulin

IPC分类号： G01V3/00 ,  A61B5/055

CPC分类号： G01R33/5611 ,  G01R33/56375

摘要： A method and apparatus for producing an image from an extended volume of interest within a subject using a Magnetic Resonance Imaging (MRI) system are provided. The method comprises translating the volume using a positioning device along an axis of the MRI system. A plurality of MR signals are detected from at least one radiofrequency (RF) coil array for a given field-of-view within the MRI system as the positioning device is translated. The plurality of MR signals are sent to a plurality of receivers wherein the receivers are each adapted to adjust their respective center frequencies at a rate commensurate with a rate of translation of the positioning device. A plurality of respective sub-images corresponding to the plurality MR signals for each of the plurality of receivers are combined to form a composite image of the volume of interest.

摘要翻译： 提供了一种用于使用磁共振成像（MRI）系统从受试者内的扩展感兴趣体积产生图像的方法和装置。 该方法包括使用定位装置沿着MRI系统的轴平移体积。 当定位装置被平移时，从用于MRI系统内的给定视野的至少一个射频（RF）线圈阵列检测多个MR信号。 多个MR信号被发送到多个接收机，其中接收机各自适于以与定位设备的平移速率相称的速率调整它们各自的中心频率。 对应于多个接收机中的每一个的多个MR信号的多个相应子图像被组合以形成感兴趣体积的合成图像。

公开(公告)号：US06876199B2

公开(公告)日：2005-04-05

申请号：US10452095

申请日：2003-05-30

申请人： Christopher Judson Hardy ,  Charles Lucian Dumoulin

发明人： Christopher Judson Hardy ,  Charles Lucian Dumoulin

IPC分类号： G01R33/34 ,  A61B5/055 ,  G01R33/3415 ,  G01R33/54 ,  G01R33/561 ,  G01V3/00

CPC分类号： G01R33/3415 ,  G01R33/5611

摘要： A method of and system for parallel imaging using a Magnetic Resonance Imaging (MRI) system is provided. The method comprises acquiring a plurality of magnetic resonance (MR) signals from a receiver coil array placed about a subject in the MRI system, where the receiver coil array has a plurality of receiver elements arranged in rows and, during application of a readout gradient in a frequency encoding direction, shifting receiver frequencies by a selectable amount for each row of the array in order to shift a limited field of view (FOV) in the frequency encoding direction.

摘要翻译： 提供了一种使用磁共振成像（MRI）系统并行成像的方法和系统。 该方法包括从MRI系统中围绕被摄体放置的接收器线圈阵列获取多个磁共振（MR）信号，其中接收器线圈阵列具有排列成行的多个接收器元件，并且在读出梯度 频率编码方向，为了在频率编码方向上移动有限的视场（FOV），将接收机频率移动到阵列的每一行的可选择量。

公开(公告)号：US06687530B2

公开(公告)日：2004-02-03

申请号：US09683394

申请日：2001-12-21

申请人： Charles Lucian Dumoulin

发明人： Charles Lucian Dumoulin

IPC分类号： A61B5055

CPC分类号： A61B5/055 ,  A61B5/06 ,  G01R33/285

摘要： A method and system for tracking the location of a device within the field of view of a Magnetic Resonance Imaging (MRI) system are provided. The method comprises computing a centroid of signal intensity in a region centered about a location of maximum signal intensity, Lmax of acquired magnetic resonance (MR) signals corresponding to the device.

摘要翻译： 提供了一种用于跟踪在磁共振成像（MRI）系统的视野内的设备的位置的方法和系统。 该方法包括在以最大信号强度的位置为中心的区域中计算信号强度的质心，所述区域与所述装置对应的获取的磁共振（MR）信号的Lmax。

公开(公告)号：US06584337B2

公开(公告)日：2003-06-24

申请号：US09683124

申请日：2001-11-21

申请人： Charles Lucian Dumoulin ,  Yudong Zhu

发明人： Charles Lucian Dumoulin ,  Yudong Zhu

IPC分类号： A61B5055

CPC分类号： A61B5/055

摘要： A method and apparatus for producing an image from an extended volume of interest using a Magnetic Resonance Imaging (MRI) system are provided. The apparatus comprises a magnet assembly, a gradient coil assembly, at least one radiofrequency coil, a positioning device for translating the volume using along an axis of the MRI system and a plurality of receivers. A plurality of MR signals are detected from the radiofrequency (RF) coil, as the positioning device is translated, and are sent to the plurality of receivers. Each of the receivers are configured to be adjusted in either phase or frequency in response to the positioning device being translated. A plurality of respective sub-images are computed corresponding to the plurality of MR signals for each of the receivers and for the given field-of-view (FOV) at each of the incremented positions. A composite image of the volume of interest is formed by combining the respective sub-images.

摘要翻译： 提供了使用磁共振成像（MRI）系统从扩展的感兴趣体积生成图像的方法和装置。 该装置包括磁体组件，梯度线圈组件，至少一个射频线圈，用于使用沿着MRI系统的轴平移体积的定位装置和多个接收器。 当定位装置被转换时，从射频（RF）线圈检测多个MR信号，并将其发送到多个接收机。 每个接收器被配置为响应于被平移的定位装置在任一阶段或频率中进行调整。 对应于每个接收机的多个MR信号以及在每个递增位置处的给定视场（FOV），对多个相应的子图像进行计算。 通过组合各个子图像来形成感兴趣体积的合成图像。

公开(公告)号：US06175757B1

公开(公告)日：2001-01-16

申请号：US09017573

申请日：1998-02-02

申请人： Ronald Dean Watkins ,  Charles Lucian Dumoulin ,  Robert David Darrow ,  Christine Elise Dumoulin

发明人： Ronald Dean Watkins ,  Charles Lucian Dumoulin ,  Robert David Darrow ,  Christine Elise Dumoulin

IPC分类号： A61B812

CPC分类号： A61B8/12 ,  A61B5/055 ,  A61B5/06 ,  A61B5/062 ,  A61B8/4245 ,  A61B8/4461 ,  Y10S128/916

摘要： An invasive probe for mapping the walls of a lumen employs a real-time tracking means and a wall distance measurement means. As the probe is advanced within the lumen, the real-time tracking means provides three-dimensional coordinates of the probe's position and orientation. Concurrent with probe localization, the distance between the probe and the lumen walls is measured. Both the probe position and the wall distance measurement are sent to a data acquisition system which in turn provides a graphic or numeric display to the operator. Probe tracking can be performed with radio-frequency, magnetic resonance, ultrasonic techniques or the like. If desired, lumen wall distance measurements can be performed with magnetic resonance or ultrasound methods. Lumen wall distance measurements can also be performed with mechanical devices such as balloons and/or expanding structures.

摘要翻译： 用于映射管腔壁的入侵探针采用实时跟踪装置和壁距测量装置。 当探头在管腔内前进时，实时跟踪装置提供探头位置和方位的三维坐标。 与探头定位同时测量探头与腔壁之间的距离。 探头位置和墙壁距离测量都发送到数据采集系统，该系统又向操作员提供图形或数字显示。 可以使用射频，磁共振，超声波技术等进行探测跟踪。 如果需要，可以用磁共振或超声波方法进行管腔壁距离测量。 腔壁距离测量也可以用诸如球囊和/或膨胀结构的机械装置进行。

公开(公告)号：US07948385B2

公开(公告)日：2011-05-24

申请号：US12330590

申请日：2008-12-09

申请人： Radislav Alexandrovich Potyrailo ,  William Guy Morris ,  Charles Lucian Dumoulin ,  Cheryl Margaret Surman

发明人： Radislav Alexandrovich Potyrailo ,  William Guy Morris ,  Charles Lucian Dumoulin ,  Cheryl Margaret Surman

IPC分类号： G08B13/14

CPC分类号： G01L9/007 ,  G06K7/10316 ,  G06K19/0716 ,  G06K19/0723

摘要： The present invention related to devices and methods for using ferrite alignment keys in wireless remote sensor assemblies. In one aspect, the invention provides wireless resonant sensor assemblies comprising a pick-up coil, a ferrite alignment key positioned in and extending from the pick-up coil, and wireless resonant sensor having a receiving element wherein the pick-up coil and the wireless resonant sensor align upon insertion of the ferrite alignment key into the receiving element. The ferrite alignment key may also be part of a resonant sensor such that insertion of a pick-up coil into a receiving element of the alignment key results in a configuration where the alignment key is positioned in and extended from the pick-up coil. Methods of measuring one or more parameters of a monitoring system are also provided. The insertion of the ferrite alignment key aligns the pick-up coil and wireless resonant sensor thereby increasing sensing of the wireless resonant sensor by the pick-up coil.

摘要翻译： 本发明涉及在无线遥控传感器组件中使用铁氧体对准键的装置和方法。 一方面，本发明提供了无线谐振传感器组件，其包括拾取线圈，位于拾取线圈中并从拾取线圈延伸的铁氧体对准键，以及具有接收元件的无线谐振传感器，其中拾取线圈和无线 谐振传感器在将铁氧体对准键插入接收元件时对准。 铁氧体对准键也可以是谐振传感器的一部分，使得拾取线圈插入到对准键的接收元件中，导致对准键位于拾取线圈中并从拾取线圈延伸的配置。 还提供了测量监测系统的一个或多个参数的方法。 铁氧体对准键的插入使得拾取线圈和无线谐振传感器对准，从而增加了拾音线圈对无线谐振传感器的感测。

公开(公告)号：US07282915B2

公开(公告)日：2007-10-16

申请号：US10962819

申请日：2004-10-07

申请人： Randy Otto John Giaquinto ,  Harvey Ellis Cline ,  Christopher Judson Hardy ,  Charles Lucian Dumoulin ,  Paul Arthur Bottomley

发明人： Randy Otto John Giaquinto ,  Harvey Ellis Cline ,  Christopher Judson Hardy ,  Charles Lucian Dumoulin ,  Paul Arthur Bottomley

IPC分类号： G01V3/00

CPC分类号： G01R33/3415 ,  G01R33/34007

摘要： An RF coil assembly for use in a multiple receive-channel MRI system is provided. The RF coil assembly is configured as a multi-turn-element RF coil assembly to operate as a surface-coil array in cooperation with the MRI system which is configured to operate in a multiple-channel receive mode.

摘要翻译： 提供了一种用于多接收信道MRI系统的RF线圈组件。 RF线圈组件被配置为多匝元件RF线圈组件，以与被配置为在多通道接收模式中操作的MRI系统协作操作作为表面线圈阵列。

公开(公告)号：US06571020B1

公开(公告)日：2003-05-27

申请号：US09603536

申请日：1999-11-12

申请人： Charles Lucian Dumoulin ,  Robert David Darrow

发明人： Charles Lucian Dumoulin ,  Robert David Darrow

IPC分类号： G06K940

CPC分类号： G01S7/52034

摘要： Secondary data set information is incorporated into a primary data set (such as a digital image) retaining a desired dynamic range and retaining the original primary set data quality. The secondary data set information is ‘smuggled’ into the least significant bits of the primary data set to result in an enhanced data set. If desired, the primary data word can be shifted toward the most significant bit. The enhanced data set may be viewed as if it were the original primary data set with existing playback devices, however it now includes additional ‘smuggled’ information which may be played back in coordination with the primary data set information. One example is flow-direction information ‘smuggled’ into an angiographic image. The least significant bits of the enhanced data words may be used to select the color map and color code the images. A user-adjustable intensity threshold can also be employed to select between color maps. Information stored in this fashion results in a substantial savings in disk storage requirements. Also, since the information of the primary and secondary data sets are merged into a single word, they will remain together throughout many different types of processing, such as maximum intensity projection in volumetric imaging.

摘要翻译： 次要数据集信息被并入保留所需动态范围并保留原始主要数据质量的主数据集（例如数字图像）中。 辅助数据集信息被“走私”到主数据集的最低有效位以产生增强的数据集，如果需要，可以将主数据字移向最高有效位，增强数据集可以被看到 好像它是现有播放设备的原始主要数据集，但是它现在包括可以与主数据集信息配合播放的其他“走私”信息。 一个例子是“走私”到血管造影图像中的流向信息，增强数据字的最低有效位可以用于选择彩色图和彩色图像，还可以使用用户可调节的强度阈值来选择 以这种方式存储的信息可以大大节省磁盘存储要求，而且由于主数据集和辅助数据集的信息被合并成一个单词，它们将保持在许多不同类型的处理中，例如 作为体积成像中的最大强度投影。

公开(公告)号：US06288541B1

公开(公告)日：2001-09-11

申请号：US09378934

申请日：1999-08-23

申请人： Charles Lucian Dumoulin

发明人： Charles Lucian Dumoulin

IPC分类号： G01V300

CPC分类号： G01R33/56308 ,  G01R33/4835 ,  G01R33/56316

摘要： An MRI system repeatedly performs a pulse sequence during a time interval &Dgr;T in which a surge of blood flows through a vessel whose compliance is to be measured. Two spaced-apart slices are simultaneously excited by each pulse sequence and the transverse magnetization is flow-encoded before an NMR signal is acquired in the presence of a readout gradient pulse. The change in phase of the NMR signal is used to detect when the wave arrives at each slice location, and from this information blood vessel compliance may be calculated.

摘要翻译： MRI系统在时间间隔DELTAT期间重复地执行脉冲序列，其中血液涌动通过要测量其顺应性的血管。 两个间隔开的切片同时被每个脉冲序列激发，并且在存在读出梯度脉冲之前获得NMR信号之前，横向磁化被流式编码。 NMR信号的相位变化用于检测波在每个切片位置何时到达，并且可以从该信息计算血管顺应性。