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    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    1.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5326371A

    公开(公告)日：1994-07-05

    申请号：US925589

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。

    Prosthetic heart valve holder
    4.
    发明授权
    Prosthetic heart valve holder 失效
    假心脏瓣膜支架

    公开(公告)号：US5531785A

    公开(公告)日：1996-07-02

    申请号：US239345

    申请日：1994-05-06

    申请人： Jack W. Love ,  Charles S. Love ,  Philip J. Hudak ,  Robert W. Suggitt

    发明人： Jack W. Love ,  Charles S. Love ,  Philip J. Hudak ,  Robert W. Suggitt

    IPC分类号： A61F2/24 ,  A61B17/00

    CPC分类号： A61F2/2427 ,  Y10S623/90

    摘要： The present invention provides a prosthetic heart valve holder specifically configured to hold a prosthetic heart valve comprised of a stent. The heart valve holder assembly has three main components: a handle, a valve capture loop assembly and a valve retainer. The prosthetic heart valve is secured to the valve retainer by a loop of suture as the surgeon sutures or attaches the valve to the annulus of the heart. Thus, the valve holder assembly facilitates attachment of the prosthetic valve to the annulus so that the procedure may be performed in a time and labor efficient manner.

    摘要翻译： 本发明提供了一种专门构造成保持由支架组成的假体心脏瓣膜的假体心脏瓣膜保持器。 心脏瓣膜保持器组件具有三个主要部件：手柄，阀捕获环组件和阀保持器。 当外科医生缝合或将瓣膜附接到心脏的环上时，假体心脏瓣膜通过缝合线固定到瓣膜保持器。 因此，阀保持器组件便于将人造瓣膜附接到环空，从而可以以时间和劳动的方式执行该过程。

    Stents for autologous tissue heart valve
    5.
    发明授权
    Stents for autologous tissue heart valve 失效
    自体组织心脏瓣膜支架

    公开(公告)号：US5755782A

    公开(公告)日：1998-05-26

    申请号：US169336

    申请日：1993-12-17

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2415 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2472 ,  Y10S623/90

    摘要： An improved set of stents for autologous tissue heart valves is provided. The stents are designed with the aid of a computer-aided-design (CAD) system, and nest within each other to securely clamp a piece of tissue which forms the leaflets of the heart valve. The geometrical features of the stents are designed to provide uniform nesting between the stents to prevent the formation of stress raisers on the tissue. Additionally, the windows in the stent posts are narrowed to prevent the suturing needle used during implantation of the valve from becoming lodged in the garter springs which clamp the outer stent to the inner stent. Finally, the sock covering the outer stent is bonded to the stent base at both upper and lower locations to isolate the bonds from the patient's blood flow.

    摘要翻译： 提供了一套改进的自体组织心脏瓣膜支架。 支架是借助于计算机辅助设计（CAD）系统设计的，并且彼此嵌套，以牢固地夹紧形成心脏瓣膜传单的一块组织。 支架的几何特征被设计成在支架之间提供均匀的嵌套，以防止在组织上形成应力集中器。 此外，支架柱中的窗口变窄，以防止在植入瓣膜期间使用的缝合针插入到将支架夹持在内支架上的套管弹簧中。 最后，覆盖外支架的袜子在上部和下部位置处与支架基座结合，以将粘合物与病人的血流隔离开来。

    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure
    7.
    发明授权
    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure 失效
    快速组装同心配合支架，组织心脏瓣膜增强夹紧和组织暴露

    公开(公告)号：US5489298A

    公开(公告)日：1996-02-06

    申请号：US400466

    申请日：1995-03-07

    申请人： Charles S. Love ,  Jack W. Love

    发明人： Charles S. Love ,  Jack W. Love

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2472 ,  A61F2/2412 ,  A61F2/2415 ,  Y10S623/90

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. The valve comprises at least one piece of tissue clamped between an inner and an outer stent. The outer stent is configured with a plurality of spaced posts extending from a base, wherein the posts are configured with open windows so that at least a portion of the tissue in the assembled valve is exposed through the windows. Several embodiments of the outer stent are disclosed, including where the outer stent comprises a crimped metal wire frame covered with a Dacron tube.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 该阀包括夹在内支架和外支架之间的至少一片组织。 外支架构造有从基部延伸的多个间隔开的柱，其中柱被构造成具有开放的窗口，使得组装的阀中的组织的至少一部分通过窗户暴露。 公开了外支架的几个实施例，包括外支架包括被涤纶管覆盖的卷曲金属线框架的位置。

    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    8.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5423887A

    公开(公告)日：1995-06-13

    申请号：US925380

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。

    Test device for and method of testing rapid assembly tissue heart valve
    10.
    发明授权
    Test device for and method of testing rapid assembly tissue heart valve 失效
    快速组装心脏瓣膜的测试装置和测试方法

    公开(公告)号：US5662705A

    公开(公告)日：1997-09-02

    申请号：US610809

    申请日：1996-03-07

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A method of manufacturing and testing a tissue heart valve during open heart surgery is disclosed. A piece of autologous tissue from the body of the patient is precisely cut according to the size of the open annulus remaining after excision of the patient's heart valve, with a plurality of holes being formed in the tissue. The tissue is situated between appropriately selected first and second stents so that the holes are registered with corresponding tissue alignment members in one of the stents, and the stents are positioned together to securely clamp the tissue therebetween. The constructed tissue heart valve is then mounted in a test chamber and visually inspected for leakage.

    摘要翻译： 公开了一种在开心手术期间制造和测试组织心脏瓣膜的方法。 根据患者心脏瓣膜切除后残留的开放环的大小精确地切割来自患者身体的一块自体组织，其中在组织中形成多个孔。 组织位于适当选择的第一和第二支架之间，使得孔与其中一个支架中的相应的组织对准构件对准，并且支架被定位在一起以将组织牢固地夹在其间。 然后将构造的组织心脏瓣膜安装在测试室中并目视检查渗漏。