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    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    1.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5326371A

    公开(公告)日：1994-07-05

    申请号：US925589

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。

    Distal anastomosis system
    2.
    发明授权
    Distal anastomosis system 失效
    远端吻合系统

    公开(公告)号：US06972023B2

    公开(公告)日：2005-12-06

    申请号：US10122075

    申请日：2002-04-11

    申请人： James G. Whayne ,  Alexander Q. Tilson ,  Sidney D. Fleischman ,  Charles S. Love

    发明人： James G. Whayne ,  Alexander Q. Tilson ,  Sidney D. Fleischman ,  Charles S. Love

    IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/064 ,  A61B17/068 ,  A61B17/11 ,  A61B17/30 ,  A61B17/08

    CPC分类号： A61B17/11 ,  A61B17/0206 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/30 ,  A61B2017/00243 ,  A61B2017/0243 ,  A61B2017/1107 ,  A61B2017/1135

    摘要： Distal anastomosis devices and associated methodology are described herein. Connector and connector components as well as tools associated therewith are disclosed. The connectors are preferably adapted to produce an end-to-side anastomosis at a graft/coronary artery junction. A fitting alone, or a fitting in combination with a collar may be used as a connector. Each fitting may be deployed by deflecting its shape to provide clearance for a rear segment that rotates about adjoining hinge section(s) so to fit the connector within an aperture formed in a host vessel. Upon return to a substantially relaxed position, a rear segment anchors the fitting it in place. The distal fitting may include additional side features for interfacing with the host vessel/coronary artery. The collar may include features complimentary to those of a fitting and provisions for securing the graft vessel.

    摘要翻译： 本文描述了远端吻合装置和相关方法。 公开了连接器和连接器部件以及与其相关联的工具。 连接器优选适于在移植物/冠状动脉交界处产生端对侧吻合。 单独的配件或与套环组合的配件可以用作连接器。 每个配件可以通过偏转其形状来部署，以便为围绕相邻的铰链部分旋转的后部段提供间隙，以便将连接器装配在形成在主机容器中的孔内。 在返回到基本松弛的位置时，后部段将其安装在适当的位置。 远端配件可以包括用于与宿主血管/冠状动脉接口的附加侧部特征。 套环可以包括与配件相匹配的特征和用于固定移植物容器的装置。

    Stents for autologous tissue heart valve
    4.
    发明授权
    Stents for autologous tissue heart valve 失效
    自体组织心脏瓣膜支架

    公开(公告)号：US5755782A

    公开(公告)日：1998-05-26

    申请号：US169336

    申请日：1993-12-17

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2415 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2472 ,  Y10S623/90

    摘要： An improved set of stents for autologous tissue heart valves is provided. The stents are designed with the aid of a computer-aided-design (CAD) system, and nest within each other to securely clamp a piece of tissue which forms the leaflets of the heart valve. The geometrical features of the stents are designed to provide uniform nesting between the stents to prevent the formation of stress raisers on the tissue. Additionally, the windows in the stent posts are narrowed to prevent the suturing needle used during implantation of the valve from becoming lodged in the garter springs which clamp the outer stent to the inner stent. Finally, the sock covering the outer stent is bonded to the stent base at both upper and lower locations to isolate the bonds from the patient's blood flow.

    摘要翻译： 提供了一套改进的自体组织心脏瓣膜支架。 支架是借助于计算机辅助设计（CAD）系统设计的，并且彼此嵌套，以牢固地夹紧形成心脏瓣膜传单的一块组织。 支架的几何特征被设计成在支架之间提供均匀的嵌套，以防止在组织上形成应力集中器。 此外，支架柱中的窗口变窄，以防止在植入瓣膜期间使用的缝合针插入到将支架夹持在内支架上的套管弹簧中。 最后，覆盖外支架的袜子在上部和下部位置处与支架基座结合，以将粘合物与病人的血流隔离开来。

    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure
    6.
    发明授权
    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure 失效
    快速组装同心配合支架，组织心脏瓣膜增强夹紧和组织暴露

    公开(公告)号：US5489298A

    公开(公告)日：1996-02-06

    申请号：US400466

    申请日：1995-03-07

    申请人： Charles S. Love ,  Jack W. Love

    发明人： Charles S. Love ,  Jack W. Love

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2472 ,  A61F2/2412 ,  A61F2/2415 ,  Y10S623/90

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. The valve comprises at least one piece of tissue clamped between an inner and an outer stent. The outer stent is configured with a plurality of spaced posts extending from a base, wherein the posts are configured with open windows so that at least a portion of the tissue in the assembled valve is exposed through the windows. Several embodiments of the outer stent are disclosed, including where the outer stent comprises a crimped metal wire frame covered with a Dacron tube.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 该阀包括夹在内支架和外支架之间的至少一片组织。 外支架构造有从基部延伸的多个间隔开的柱，其中柱被构造成具有开放的窗口，使得组装的阀中的组织的至少一部分通过窗户暴露。 公开了外支架的几个实施例，包括外支架包括被涤纶管覆盖的卷曲金属线框架的位置。

    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    7.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5423887A

    公开(公告)日：1995-06-13

    申请号：US925380

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。

    Method and apparatus for forming vascular prostheses
    10.
    发明授权
    Method and apparatus for forming vascular prostheses 失效
    用于形成血管假体的方法和装置

    公开(公告)号：US06494904B1

    公开(公告)日：2002-12-17

    申请号：US09091942

    申请日：1998-12-10

    申请人： Charles S. Love

    发明人： Charles S. Love

    IPC分类号： A61F206

    CPC分类号： A61F2/88 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0017 ,  A61F2230/005

    摘要： A vascular prosthesis (10) comprises pericardial, fascial, or other tissue (12) formed over a tubular support frame. A first exemplary tubular support frame comprises an inner helical member (16) and an outer helical member (14), where the tissue is rolled and captured therebetween. A second exemplary tubular support frame (60, 62) comprises a plurality of ring elements (64, 72) which are located alternately on the outside and on the inside of the rolled tissue. Other exemplary frames employ fasteners (84, 98) for penetrating the rolled tissue and attaching tissue to frame elements. The tissue is preferably obtained from the patient who is to receive the vascular prosthesis, with the tissue being mounted over the frame immediately prior to use.

    摘要翻译： 血管假体（10）包括在管状支撑框架上形成的心包，筋膜或其他组织（12）。 第一示例性管状支撑框架包括内螺旋构件（16）和外螺旋构件（14），其中组织被卷起并在其间捕获。 第二示例性管状支撑框架（60,62）包括多个环形元件（64,72），所述多个环形元件交替地位于所轧制的组织的外侧和内侧。 其它示例性框架采用紧固件（84,98），用于穿透轧制的组织并将组织附着到框架元件。 组织优选地从要接收血管假体的患者获得，其中组织在使用之前立即安装在框架上。