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1.发明申请SYSTEMS AND METHODS OF CONSTRUCTING A PATIENT SPECIFIC NEURAL ELECTRICAL STIMULATION MODEL 审中-公开建立患者特异性神经电刺激模型的系统和方法公开(公告)号：US20120116741A1
公开(公告)日：2012-05-10
申请号：US13110771
申请日：2011-05-18
IPC分类号： G06G7/60
CPC分类号： G09B23/30 , A61B5/04001 , A61N1/36135
摘要： A system and a method of constructing a personalized or patient specific neural stimulation model. The method includes measuring an electro-physiology signal of an individual and establishing a personalized or patient specific neural stimulation model that has a preset model parameter and generates a human physiology parameter according to the model parameters; and analyzing the human physiology parameters and regulating the model parameters according to a parameter-optimizing algorithm, such that the human physiology parameters outputted by the personalized or patient specific neural stimulation model matches the measured electro-physiology signal.
摘要翻译： 构建个性化或患者特异性神经刺激模型的系统和方法。 该方法包括测量个体的电生理信号并建立具有预设模型参数的个性化或患者特异性神经刺激模型，并根据模型参数生成人体生理参数; 并根据参数优化算法分析人体生理参数和调节模型参数，使得个性化或患者特异性神经刺激模型输出的人体生理参数与测得的电生理信号匹配。
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公开(公告)号：US20100292751A1
公开(公告)日：2010-11-18
申请号：US12627192
申请日：2009-11-30
CPC分类号： A61N1/36071 , A61N1/36036 , A61N1/36082 , A61N1/37235 , G06F19/00 , G16H40/63
摘要： A parameter adjustment device and method thereof for a stimulator is disclosed. The parameter adjustment device comprises a generation unit, a user interface and a process unit. The generation unit generates a test MAP based on a current MAP. The user interface displays the current MAP and the test MAP for choosing one of them as the preferred MAP, and displays a major and a minor for choosing again, the major and the minor is defined as a significant difference and a little difference between the test MAP and the current MAP respectively. The process unit computes the acceptance probability of the preferred MAP based on a major or minor probability correspondence relationship and determines a next MAP by comparing the acceptance probability with the test probability. When one of the termination conditions is satisfied in an iterative operation, the next MAP is outputted as the best MAP.
摘要翻译： 公开了一种用于刺激器的参数调整装置及其方法。 参数调整装置包括生成单元，用户界面和处理单元。 生成单元基于当前MAP生成测试MAP。 用户界面显示当前MAP和测试MAP，选择其中一个作为首选MAP，并显示主要和次要选择，主要和次要被定义为显着差异和测试之间的一点差异 MAP和当前MAP。 处理单元基于主要或次要概率对应关系来计算优选MAP的接受概率，并通过将接受概率与测试概率进行比较来确定下一MAP。 当在迭代操作中满足终止条件之一时，将下一MAP作为最佳MAP输出。
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公开(公告)号：US08666503B2
公开(公告)日：2014-03-04
申请号：US12627192
申请日：2009-11-30
IPC分类号： A61N1/36
CPC分类号： A61N1/36071 , A61N1/36036 , A61N1/36082 , A61N1/37235 , G06F19/00 , G16H40/63
摘要： A parameter adjustment device and method thereof for a stimulator is disclosed. The parameter adjustment device comprises a generation unit, a user interface and a process unit. The generation unit generates a test MAP based on a current MAP. The user interface displays the current MAP and the test MAP for choosing one of them as the preferred MAP, and displays a major and a minor for choosing again, the major and the minor is defined as a significant difference and a little difference between the test MAP and the current MAP respectively. The process unit computes the acceptance probability of the preferred MAP based on a major or minor probability correspondence relationship and determines a next MAP by comparing the acceptance probability with the test probability. When one of the termination conditions is satisfied in an iterative operation, the next MAP is outputted as the best MAP.
摘要翻译： 公开了一种用于刺激器的参数调整装置及其方法。 参数调整装置包括生成单元，用户界面和处理单元。 生成单元基于当前MAP生成测试MAP。 用户界面显示当前MAP和测试MAP，选择其中一个作为首选MAP，并显示主要和次要选择，主要和次要被定义为显着差异和测试之间的一点差异 MAP和当前MAP。 处理单元基于主要或次要概率对应关系来计算优选MAP的接受概率，并通过将接受概率与测试概率进行比较来确定下一MAP。 当在迭代操作中满足终止条件之一时，将下一MAP作为最佳MAP输出。
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公开(公告)号：US08340758B2
公开(公告)日：2012-12-25
申请号：US12358539
申请日：2009-01-23
IPC分类号： A61N1/00
CPC分类号： A61N1/36036 , A61N1/0541 , Y10T307/576 , Y10T307/587
摘要： An apparatus and method for controlling an electrical stimulation system to increase the resolution of the stimulation region with multiple independent power source electrodes is proposed. In the apparatus, the electrode set contains at least three electrodes of which two adjacent electrodes are of the same power polarity to control the location of the composite stimulation signal and the others are of an inverse power polarity to balance the total power polarity and narrow the stimulation region. The method for the apparatus comprises steps of: receiving a target stimulation location and level, generating at least one parameter to adjust power settings of the electrodes, thereby obtaining a composite stimulation signal corresponding to a virtual channel of which a location and level match the target stimulation location and level.
摘要翻译： 提出了一种用于控制电刺激系统以增加具有多个独立电源电极的刺激区域的分辨率的装置和方法。 在该装置中，电极组包含至少三个电极，其两个相邻的电极具有相同的功率极性，以控制复合刺激信号的位置，并且其它电极具有反向功率极性，以平衡总功率极性并使 刺激区域。 该装置的方法包括以下步骤：接收目标刺激位置和电平，产生至少一个参数以调节电极的功率设置，从而获得对应于位置和电平与目标相匹配的虚拟信道的复合刺激信号 刺激位置和水平。
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5.发明申请公开(公告)号：US20100076521A1
公开(公告)日：2010-03-25
申请号：US12461944
申请日：2009-08-28
IPC分类号： A61N1/08
CPC分类号： A61N1/0558 , A61N1/0534 , A61N1/0541 , A61N1/0543 , A61N1/0551 , A61N1/3605 , A61N1/36067 , A61N1/36071
摘要： Electrical stimulation system and method for generating virtual channels are disclosed. The electrical stimulation system comprises: an electrode controller, a carrier, a plurality of electrode units, and a buffer layer. The electrode units are disposed on the carrier, and each of the electrode units are electrically connected to the electrode controller independently. Besides, the electrode units and the carrier are covered with the buffer layer. When the electrode controller receive a control signal and drive the corresponding electrode units, the electrical currents output from the corresponding electrode units can electrically interfere with each other to generate a virtual channel between the corresponding electrode units.
摘要翻译： 公开了用于产生虚拟通道的电刺激系统和方法。 电刺激系统包括：电极控制器，载体，多个电极单元和缓冲层。 电极单元设置在载体上，并且每个电极单元独立地电连接到电极控制器。 此外，电极单元和载体被缓冲层覆盖。 当电极控制器接收到控制信号并驱动相应的电极单元时，从相应的电极单元输出的电流可以彼此电干扰以在对应的电极单元之间产生虚拟通道。
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