利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

13 条记录 (耗时 0.027 秒)

    Method and Compositions for Treatment or Prevention of Inflammatory Conditions
    1.
    发明申请
    Method and Compositions for Treatment or Prevention of Inflammatory Conditions 有权
    治疗或预防炎症病症的方法和组成

    公开(公告)号：US20140296273A1

    公开(公告)日：2014-10-02

    申请号：US14191219

    申请日：2014-02-26

    申请人： Chen Yan ,  Jian-Dong Li ,  Bradford Berk ,  Kye-Im Jeon ,  Xiangbin Xu

    发明人： Chen Yan ,  Jian-Dong Li ,  Bradford Berk ,  Kye-Im Jeon ,  Xiangbin Xu

    IPC分类号： A61K31/4375

    CPC分类号： A61K31/4375 ,  A61K9/0046 ,  A61K31/573 ,  A61K45/06 ,  A61K2300/00

    摘要： Pharmaceutical compositions and methods for treating or preventing an inflammatory condition in a patient are disclosed. The pharmaceutical compositions and methods include the use of vincamine or a vincamine derivative, either alone or in combination with one or more additional therapeutic agents, including a steroid (preferably a corticosteroid), an angiotensin II receptor (type 1) antagonist, an angiotensin-converting enzyme (ACE) inhibitor, and a non-steroidal anti-inflammatory drug.

    摘要翻译： 公开了用于治疗或预防患者炎症状况的药物组合物和方法。 药物组合物和方法包括使用长春胺或长春胺衍生物，单独或与一种或多种另外的治疗剂组合使用，包括类固醇（优选皮质类固醇），血管紧张素II受体（1型）拮抗剂，血管紧张素 - 转化酶（ACE）抑制剂和非甾体抗炎药。

    METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE
    3.
    发明申请
    METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE 审中-公开
    治疗或预防心律失常重塑和心脏衰竭的方法和组合

    公开(公告)号：US20110190373A1

    公开(公告)日：2011-08-04

    申请号：US12991345

    申请日：2009-05-05

    申请人： Chen Yan ,  Jian-Dong Li

    发明人： Chen Yan ,  Jian-Dong Li

    IPC分类号： A61K31/475 ,  A61K31/7088 ,  A61K31/522 ,  A61P9/00

    CPC分类号： A61K31/4745

    摘要： The invention relates to methods of treating or preventing pathological cardiac remodeling and/or preventing heart failure. These methods include the administration of a PDE1 inhibitor to a patient under conditions effective to treat or prevent pathological cardiac remodeling, and therefore heart failure that occurs as a result of such remodeling. Pharmaceutical compositions and delivery vehicles that can be used in the methods of the present invention are also disclosed herein.

    摘要翻译： 本发明涉及治疗或预防病理性心脏重塑和/或预防心力衰竭的方法。 这些方法包括在有效治疗或预防病理性心脏重塑的病症下向患者施用PDE1抑制剂，因此由于这种重塑而发生的心力衰竭。 可用于本发明方法的药物组合物和递送载体也在本文中公开。

    Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
    6.
    发明授权
    Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis 失效
    使用抗菌蛋白和肽治疗中耳炎和鼻旁窦炎

    公开(公告)号：US06716813B2

    公开(公告)日：2004-04-06

    申请号：US09998547

    申请日：2001-11-27

    申请人： David J. Lim ,  Haa-Yung Lee ,  Paul Webster ,  Ali Andalibi ,  Jian-Dong Li ,  Tomas Ganz

    发明人： David J. Lim ,  Haa-Yung Lee ,  Paul Webster ,  Ali Andalibi ,  Jian-Dong Li ,  Tomas Ganz

    IPC分类号： A61K3800

    CPC分类号： A61K38/40 ,  A61K38/1729 ,  A61K38/47 ,  A61K2300/00

    摘要： Disclosed herein is a method for the treatment of otitis media and paranasal sinusitis using human defensins, lysozyme and/or lactoferrin as a new class of non-antibiotic antimicrobials. From studies of otitis media and paranasal sinusitis, it was observed that certain innate immune modulators were important in the bodies response to the infection. Therefore, these innate immune modulators, lysozyme, lactoferrin and defensins, were tested for use as a non-antibiotic treatment for infection, particularly infections such as otitis media and sinusitis.

    摘要翻译： 本文公开了一种使用人防御素，溶菌酶和/或乳铁蛋白作为新一类非抗生素抗微生物剂治疗中耳炎和鼻旁窦炎的方法。 从中耳炎和鼻旁窦炎的研究中，观察到某些先天免疫调节剂在身体对感染的反应中是重要的。 因此，这些先天免疫调节剂，溶菌酶，乳铁蛋白和防御素被测试用作感染的非抗生素治疗，特别是诸如中耳炎和鼻窦炎的感染。