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公开(公告)号:US08389560B2
公开(公告)日:2013-03-05
申请号:US12559818
申请日:2009-09-15
申请人: Chen-Fu Liu , Kuang-Yuan Lee , Pei-Chin Cheng , Yo-Chin Liu , Pin Lo , Kuo-Feng Tseng , Chih-Ming Chen , Chi-Hsin Richard King , Chu-Chung Lin
发明人: Chen-Fu Liu , Kuang-Yuan Lee , Pei-Chin Cheng , Yo-Chin Liu , Pin Lo , Kuo-Feng Tseng , Chih-Ming Chen , Chi-Hsin Richard King , Chu-Chung Lin
IPC分类号: A61K31/407 , C07D245/04 , C07D401/12
CPC分类号: C07K5/0804 , A61K31/4355 , A61K31/519 , A61K38/00 , C07D491/048 , C07D519/00
摘要: This invention relates to macrocyclic compounds of formula (I) shown in the specification. These compounds can be used to treat hepatitis C virus infection.
摘要翻译: 本发明涉及说明书中所示的式(I)的大环化合物。 这些化合物可用于治疗丙型肝炎病毒感染。
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公开(公告)号:US20110065737A1
公开(公告)日:2011-03-17
申请号:US12559818
申请日:2009-09-15
申请人: Chen-Fu Liu , Kuang-Yuan Lee , Pei-Chin Cheng , Yo-Chin Liu , Pin Lo , Kuo-Feng Tseng , Chih-Ming Chen , Chi-Hsin Richard King , Chu-Chung Lin
发明人: Chen-Fu Liu , Kuang-Yuan Lee , Pei-Chin Cheng , Yo-Chin Liu , Pin Lo , Kuo-Feng Tseng , Chih-Ming Chen , Chi-Hsin Richard King , Chu-Chung Lin
IPC分类号: A61K31/519 , A61K31/4355 , A61P31/12 , C07D245/00
CPC分类号: C07K5/0804 , A61K31/4355 , A61K31/519 , A61K38/00 , C07D491/048 , C07D519/00
摘要: This invention relates to macrocyclic compounds of formula (I) shown in the specification. These compounds can be used to treat hepatitis C virus infection.
摘要翻译: 本发明涉及说明书中所示的式(I)的大环化合物。 这些化合物可用于治疗丙型肝炎病毒感染。
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公开(公告)号:US20090111757A1
公开(公告)日:2009-04-30
申请号:US12254439
申请日:2008-10-20
申请人: Chu-Chung Lin , Kuang-Yuan Lee , Chen-Fu Liu , Pin Lo , Yo-Chin Liu , Yueh-chiang Han , Chi-Hsin Richard King
发明人: Chu-Chung Lin , Kuang-Yuan Lee , Chen-Fu Liu , Pin Lo , Yo-Chin Liu , Yueh-chiang Han , Chi-Hsin Richard King
CPC分类号: C07K5/0808
摘要: Compounds of formula (I): in which R1, R2, R3 R4, and R5, U, X, Y, and Z are as defined herein. Also disclosed is use of these compounds, alone or in combination with other active agents, to treat hepatitis C virus infection.
摘要翻译: 式(I)化合物:其中R 1,R 2,R 3,R 4和R 5,U,X,Y和Z如本文所定义。 还公开了这些化合物单独或与其它活性剂组合用于治疗丙型肝炎病毒感染的用途。
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