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公开(公告)号：US10981860B2
公开(公告)日：2021-04-20
申请号：US16099989
申请日：2017-05-11
发明人： Haiying He , Songliang Wu , Zhi Luo , Jianfeng Mou , Fengying Guo , Chuan Wang , Guoqing Li , Minggao Zeng , Shuhui Chen
IPC分类号： C07C225/22 , C07C225/10 , C07C225/18 , C07D205/04 , C07D207/04 , C07D221/22 , C07D221/20 , C07D221/04 , C07D223/04 , C07D265/30 , C07D267/12 , C07D401/06 , A61P43/00 , C07D409/06 , C07D211/62 , C07D451/02 , A61K31/46 , A61K31/445 , C07C237/12 , C07D211/60 , C07D207/06 , C07D227/04 , C07D239/26 , C07D333/10 , C07D333/72 , C07D413/06
摘要： Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
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公开(公告)号：US20190135733A1
公开(公告)日：2019-05-09
申请号：US16099989
申请日：2017-05-11
发明人： Haiying He , Songliang Wu , Zhi Luo , Jianfeng Mou , Fengying Guo , Chuan Wang , Guoqing Li , Minggao Zeng , Shuhui Chen
IPC分类号： C07C225/22 , C07D205/04 , C07D207/06 , C07D227/04 , C07D265/30 , C07D223/04 , C07D221/22 , C07D221/04 , C07D239/26 , C07D333/10 , C07D333/72 , C07D413/06 , C07D401/06
摘要： Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
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公开(公告)号：US11434212B2
公开(公告)日：2022-09-06
申请号：US16479673
申请日：2018-01-23
发明人： Jianfeng Mou , Songliang Wu , Haiying He , Fengying Guo , Chuan Wang , Jie Li , Jian Li , Shuhui Chen
IPC分类号： C07D261/18 , C07D231/14 , C07D233/90 , C07D263/34 , C07D271/06 , C07D277/56
摘要： A compound represented by formula (I), a pharmaceutically acceptable salt or tautomer thereof, and an application of the compound as a caspase inhibitor.
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