Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering
    1.
    发明授权
    Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering 有权
    生物可吸收袋,含有组织工程不同生物吸收率的生物可吸收材料

    公开(公告)号:US06656488B2

    公开(公告)日:2003-12-02

    申请号:US09832700

    申请日:2001-04-11

    IPC分类号: A61F200

    CPC分类号: A61L27/52 A61L27/58

    摘要: A device for tissue engineering is formed of a porous bioabsorbable bag containing at least two bioabsorbable materials having different rates of bioabsorption such as beads of different degrading rates and a bioabsorbable binding gel such as fibrin that binds the bioabsorbable materials in relation to each other. Slow degrading beads and the bag may be made of a copolymer of poly(L-lactide) and poly(glycolide), and fast degrading beads may be made of gelatin. The bag may contain cells and/or wound healing stimulants such as growth factors. Hydrolyzing enzymes may be used to enhance biodegradation of polymers. The device can be used to promote in-growth of host tissue into a void by inserting the bag with its contents into the void and conforming the bag to a desired shape. The binding gel may be injected into the bag after being placed in the void .

    摘要翻译: 用于组织工程的装置由含有至少两种具有不同生物吸收速率的生物可吸收材料(例如不同降解率的珠子)和生物可吸收结合凝胶(例如纤维蛋白)的多孔生物可吸收袋形成,其结合生物可吸收材料相互之间。 缓慢降解的珠和袋可以由聚(L-丙交酯)和聚(乙交酯)的共聚物制成,并且快速降解的珠可以由明胶制成。 袋子可以含有细胞和/或伤口愈合兴奋剂如生长因子。 水解酶可用于增强聚合物的生物降解。 该装置可用于通过将其内含物插入到空隙中并将袋符合到期望的形状来促进宿主组织的生长成为空隙。 结合凝胶在放入空隙后可以注入袋中。

    Device and method for tissue engineering
    2.
    发明申请
    Device and method for tissue engineering 有权
    组织工程的装置和方法

    公开(公告)号:US20080131477A1

    公开(公告)日:2008-06-05

    申请号:US10654145

    申请日:2003-09-03

    IPC分类号: A61F2/00 C12M1/00 A61K38/48

    CPC分类号: A61L27/52 A61L27/58

    摘要: A device and method for tissue engineering is disclosed. More particularly this invention relates to a bioabsorbable device and a method of its use which promotes controlled new tissue in-growth into voids or cavities occupied by the device as portions of the device are selectively absorbed within a host thereby minimizing collapse of surrounding, pre-existing host tissue into the engineered site.

    摘要翻译: 公开了一种用于组织工程的装置和方法。 更具体地说,本发明涉及一种生物可吸收装置及其使用方法,其促进受控的新组织生长成由装置占据的空隙或空腔,因为装置的部分选择性地吸收在主体内,从而最小化周围, 现有宿主组织进入工程现场。

    Method for promoting growth of tissue
    3.
    发明授权
    Method for promoting growth of tissue 有权
    促进组织生长的方法

    公开(公告)号:US07604817B2

    公开(公告)日:2009-10-20

    申请号:US10654145

    申请日:2003-09-03

    CPC分类号: A61L27/52 A61L27/58

    摘要: A device and method for tissue engineering is disclosed. More particularly this invention relates to a bioabsorbable device and a method of its use which promotes controlled new tissue in-growth into voids or cavities occupied by the device as portions of the device are selectively absorbed within a host thereby minimizing collapse of surrounding, pre-existing host tissue into the engineered site.

    摘要翻译: 公开了一种用于组织工程的装置和方法。 更具体地说,本发明涉及一种生物可吸收装置及其使用方法,其促进受控的新组织生长成由装置占据的空隙或空腔,因为装置的部分选择性地吸收在主体内,从而最小化周围, 现有宿主组织进入工程现场。

    Collagen matrix for soft tissue augmentation
    5.
    发明申请
    Collagen matrix for soft tissue augmentation 审中-公开
    用于软组织增生的胶原基质

    公开(公告)号:US20050142161A1

    公开(公告)日:2005-06-30

    申请号:US10748894

    申请日:2003-12-30

    摘要: The present invention includes methods and materials for soft tissue implant formed from biologically-compatible polymeric matrixes. The matrixes may have pores sized for in-growth of soft tissue. The material may be utilized with collagen or other matrix materials. This material may be used in a method of reforming soft tissues by implanting the material within soft body tissues to modify soft tissue defects such as wrinkles or biopsy tissue defects and to reshape soft tissue.

    摘要翻译: 本发明包括由生物相容的聚合物基质形成的软组织植入物的方法和材料。 基质可以具有用于软组织生长的孔。 该材料可以与胶原蛋白或其他基质材料一起使用。 该材料可用于通过将材料植入软体组织中来改变软组织以改善软组织缺陷如皱纹或活检组织缺陷并重塑软组织的方法。