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    Antimicrobial Foam Compositions, Articles and Methods
    1.
    发明申请
    Antimicrobial Foam Compositions, Articles and Methods 审中-公开
    抗菌泡沫组合物，文章和方法

    公开(公告)号：US20100260824A1

    公开(公告)日：2010-10-14

    申请号：US12548532

    申请日：2009-08-27

    申请人： Chirag B. Shah ,  Ronald F. Vitaris ,  E. David Fink ,  Scott Orr ,  Brian Dowd ,  Alain Tranchemontagne ,  Kate Ward ,  Hansen Swaniker ,  Harish A. Patel

    发明人： Chirag B. Shah ,  Ronald F. Vitaris ,  E. David Fink ,  Scott Orr ,  Brian Dowd ,  Alain Tranchemontagne ,  Kate Ward ,  Hansen Swaniker ,  Harish A. Patel

    IPC分类号： A61L15/16 ,  A61K31/785 ,  A61K38/02 ,  A61P17/02

    CPC分类号： A01N25/00 ,  A01N25/34 ,  A61F13/0203 ,  A61F2013/0091 ,  A61L15/425 ,  A61L15/46 ,  A61L2300/206 ,  A61L2300/208 ,  A61L2300/404 ,  A61L2300/608 ,  A01N33/12 ,  A01N47/44

    摘要： Articles may be formed including: at least one layer of foam, the foam layer and at least one antimicrobial agent associated with foam layer, the antimicrobial agent including PHMB, PEHMB, or derivatives thereof; at least one non-adherent layer disposed on at least a portion of the foam layer, the non-adherent layer being permeable to moisture; and a film disposed on at least another portion of the foam layer, the film being breathable to allow escape of moisture, but substantially impermeable to bacteria. Another article may include at least one layer of foam, the foam having pores of different sizes, at least some of the pores at least partially filled with at least one elutable antimicrobial agent, the pores of different sizes forming a gradient with the foam layer. Yet another article may include a foam matrix and a plurality of dissolvable members disposed with the foam matrix, at least one antimicrobial agents associated with the dissolvable members such that upon dissolution thereof the antimicrobial agent is eluted and pores or voids are created in the foam matrix. Wound dressings formed from the above articles are also described.

    摘要翻译： 可以形成制品，包括：至少一层泡沫，泡沫层和与泡沫层相关的至少一种抗微生物剂，抗微生物剂包括PHMB，PEHMB或其衍生物; 至少一个非粘附层设置在泡沫层的至少一部分上，非粘附层可渗透水分; 以及设置在泡沫层的至少另一部分上的膜，所述膜是透气的，以允许水分逸出，但是对细菌基本上不可渗透。 另一制品可以包括至少一层泡沫，泡沫具有不同尺寸的孔，至少部分至少部分填充有至少一种可消除的抗微生物剂的孔，不同尺寸的孔与泡沫层形成梯度。 另一种制品可以包括泡沫基质和与泡沫基体一起设置的多个可溶解构件，至少一种与可溶解构件相关联的抗微生物剂，使得在溶解时，抗微生物剂被洗脱，并且在泡沫基质中​​产生孔或空隙 。 还描述了由上述制品形成的伤口敷料。