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    Non-invasive positioning system for locating the focus of high-intensity focused ultrasound
    1.
    发明申请
    Non-invasive positioning system for locating the focus of high-intensity focused ultrasound 有权
    非侵入性定位系统，用于定位高强度聚焦超声的焦点

    公开(公告)号：US20070232912A1

    公开(公告)日：2007-10-04

    申请号：US11707109

    申请日：2007-02-16

    申请人： Chiung-Nien Chen ,  Po-Huang Lee ,  Wen-Shiang Chen ,  Ming-Chih Ho ,  Chih-Ching Wu

    发明人： Chiung-Nien Chen ,  Po-Huang Lee ,  Wen-Shiang Chen ,  Ming-Chih Ho ,  Chih-Ching Wu

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/08 ,  G01S7/5205 ,  G01S15/899

    摘要： A non-invasive positioning system for determining the focus location of a HIFU device comprises a diagnostic ultrasound and the HIFU for ablating and removing tumor tissue. The imaging plane of the diagnostic ultrasound probe and the geometrical axis of a probe of the HIFU define an inclining angle during operation. When the imaging plane of the diagnostic ultrasound intersected to the focus of the HIFU transducer, a maximal convergent interference signals was obtained, so as to position the HIFU focus within tumors for precise ablation.

    摘要翻译： 用于确定HIFU装置的焦点位置的无创定位系统包括诊断超声波和用于消融和去除肿瘤组织的HIFU。 诊断超声探头的成像平面和HIFU探针的几何轴在运行过程中定义倾斜角度。 当诊断超声波的成像平面与HIFU传感器的焦点相交时，获得最大的收敛干涉信号，以将HIFU焦点定位在肿瘤内用于精确的消融。

    Non-invasive positioning system for locating the focus of high-intensity focused ultrasound
    2.
    发明授权
    Non-invasive positioning system for locating the focus of high-intensity focused ultrasound 有权
    非侵入性定位系统，用于定位高强度聚焦超声的焦点

    公开(公告)号：US07955263B2

    公开(公告)日：2011-06-07

    申请号：US11707109

    申请日：2007-02-16

    申请人： Chiung-Nien Chen ,  Po-Huang Lee ,  Wen-Shiang Chen ,  Ming-Chih Ho ,  Chih-Ching Wu

    发明人： Chiung-Nien Chen ,  Po-Huang Lee ,  Wen-Shiang Chen ,  Ming-Chih Ho ,  Chih-Ching Wu

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/08 ,  G01S7/5205 ,  G01S15/899

    摘要： A non-invasive positioning system for determining the focus location of a HIFU device comprises a diagnostic ultrasound and the HIFU for ablating and removing tumor tissue. The imaging plane of the diagnostic ultrasound probe and the geometrical axis of a probe of the HIFU define an inclining angle during operation. When the imaging plane of the diagnostic ultrasound intersected to the focus of the HIFU transducer, a maximal convergent interference signals was obtained, so as to position the HIFU focus within tumors for precise ablation.

    摘要翻译： 用于确定HIFU装置的焦点位置的无创定位系统包括诊断超声波和用于消融和去除肿瘤组织的HIFU。 诊断超声探头的成像平面和HIFU探针的几何轴在运行过程中定义倾斜角度。 当诊断超声波的成像平面与HIFU传感器的焦点相交时，获得最大的收敛干涉信号，以将HIFU焦点定位在肿瘤内用于精确的消融。

    SEROLOGICAL MARKER FOR DETECTING PANCREATIC CANCER AND A METHOD FOR USING THE SEROLOGICAL MARKER
    5.
    发明申请
    SEROLOGICAL MARKER FOR DETECTING PANCREATIC CANCER AND A METHOD FOR USING THE SEROLOGICAL MARKER 审中-公开
    用于检测胰腺癌的血清学标记和使用血清学标记的方法

    公开(公告)号：US20120295288A1

    公开(公告)日：2012-11-22

    申请号：US13475658

    申请日：2012-05-18

    申请人： Jau-Song Yu ,  Ya-Ting Chang ,  Chih-Ching Wu ,  Yi-Ming Shyr ,  Yu-Sun Chang

    发明人： Jau-Song Yu ,  Ya-Ting Chang ,  Chih-Ching Wu ,  Yi-Ming Shyr ,  Yu-Sun Chang

    IPC分类号： G01N33/574 ,  H01J49/26 ,  G01N27/62

    CPC分类号： G01N33/57438

    摘要： UL16 binding protein 2 (ULBP2) is a protein overexpressed in pancreatic cancer tissues, and the ULBP2 levels are significantly higher in pancreatic cancer patients than those in healthy controls. This invention provides a method to detect pancreatic cancer using ULBP2 as a serological marker. The combination of ULBP2 and CA19-9 promotes the efficacy of pancreatic cancer detection. When measuring the blood ULBP2 levels in patients with other cancer types, including colorectal carcinoma, nasopharyngeal carcinoma and gastric cancer illustrates the blood ULBP2 levels are higher in patients with pancreatic cancer than other cancer types.

    摘要翻译： UL16结合蛋白2（ULBP2）是胰腺癌组织中过表达的蛋白质，胰腺癌患者的ULBP2水平明显高于健康对照组。 本发明提供了使用ULBP2作为血清学标记来检测胰腺癌的方法。 ULBP2和CA19-9的组合促进胰腺癌检测的功效。 当测量其他癌症类型（包括结肠直肠癌，鼻咽癌和胃癌）患者的血液ULBP2水平时，说明胰腺癌患者的血液ULBP2水平高于其他癌症类型。