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公开(公告)号:US07482366B2
公开(公告)日:2009-01-27
申请号:US10899458
申请日:2004-07-24
申请人: Christopher D Bayne , Alan T Johnson , Shao-Po Lu , Raju Mohan , Michael C Nyman , Edwin J Schweiger , William C Stevens, Jr. , Haixia Wang , Yinong Xie
发明人: Christopher D Bayne , Alan T Johnson , Shao-Po Lu , Raju Mohan , Michael C Nyman , Edwin J Schweiger , William C Stevens, Jr. , Haixia Wang , Yinong Xie
IPC分类号: A61K31/443 , A61K31/4436 , C07D409/04 , C07D405/04
CPC分类号: C07D401/12 , C07D213/84 , C07D213/85 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/04 , C07D417/06 , C07D417/12
摘要: Compounds of the invention, such as compounds of formula (I): where n, m, A, B, R1, R2, R3, R4 and R5 are defined herein, are useful as modulators of the activity of liver X receptors. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
摘要翻译: 本发明的化合物,例如式(I)的化合物:其中n,m,A,B,R 1,R 2,R 3,R 4和R 5在本文中定义,可用作肝X受体活性的调节剂。 还公开了含有化合物的药物组合物和使用该化合物的方法。
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2.
公开(公告)号:US07834004B2
公开(公告)日:2010-11-16
申请号:US12204489
申请日:2008-09-04
申请人: Stewart A. Noble , Guy Oshiro , James W. Malecha , Cunxiang Zhao , Carmen Robinson , Sergio G. Duron , Michael Sertic , Andrew K. Lindstrom , Andrew K. Shiau , Christopher D Bayne , Mehmet Kahraman , Boliang Lou , Steven P. Govek
发明人: Stewart A. Noble , Guy Oshiro , James W. Malecha , Cunxiang Zhao , Carmen Robinson , Sergio G. Duron , Michael Sertic , Andrew K. Lindstrom , Andrew K. Shiau , Christopher D Bayne , Mehmet Kahraman , Boliang Lou , Steven P. Govek
IPC分类号: A61K31/496 , A61K31/343 , A61K31/404 , A61K31/551 , A61K31/495 , C07D333/52 , C07D403/02 , C07D209/04 , C07D405/02 , C07D307/78
CPC分类号: C07D213/74 , C07D209/08 , C07D211/96 , C07D257/04 , C07D295/26 , C07D333/60 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D487/08
摘要: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
摘要翻译: 公开了作为过氧化物酶体增殖物激活受体的调节剂的化合物,包含其的药物组合物和使用其的治疗疾病的方法。
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