公开(公告)号：US5756098A

公开(公告)日：1998-05-26

申请号：US571231

申请日：1995-12-12

申请人： Christopher H. Price ,  Dale Hedtke ,  Geoffrey N. Richards ,  Michael S. Tempesta

发明人： Christopher H. Price ,  Dale Hedtke ,  Geoffrey N. Richards ,  Michael S. Tempesta

IPC分类号： C08B37/14 ,  C07D311/40 ,  C08B37/00 ,  D21C1/10 ,  D21C5/00 ,  A01N65/00 ,  A61K35/78 ,  B30B13/00 ,  C07G1/00

CPC分类号： D21C1/10 ,  C07D311/40 ,  C08B37/0036 ,  C08B37/006 ,  D21C5/00

摘要： Methods and apparatus are provided for the recovery of organic compounds from fibrous plant materials. Organic compounds which can be recovered from the fibrous plant materials include plant metabolites, such as arabinogalactan and phenols, which can be isolated from the wood, for example, of the Western Larch and Tamarack tree varieties. In addition to the recovery of organic compounds from wood, fibrous wood products also may be isolated, in the form of a clean fiber that can be used, for example, as raw material in wood processing applications or in the manufacture of high quality paper products. In one embodiment, a fibrous plant material first is compressed, to recover a liquid exudate and a first pressed plant fiber product. Optionally, the fibrous plant material, such as wood particles, is compressed in the substantial absence of any added solvent, to produce a pure normal liquid exudate and a first pressed plant product. The first plant fiber product then may be impregnated with, for example, an aqueous solvent, to recover an extract liquor and impregnated plant fiber. The impregnated plant fiber then is compressed to recover a liquid pressate and a second pressed fiber product. Using these methods, in one embodiment, a substantially pure arabinogalactan exudate and a wood fiber product can be recovered from wood of the genus Larix, with minimal coextraction of phenols. Additionally, a variety of different plant metabolites may be isolated and/or identified from different kinds of woody plants using the methods and apparatus.

摘要翻译： 提供了从纤维植物材料回收有机化合物的方法和装置。 可以从纤维性植物材料回收的有机化合物包括植物代谢物，例如阿拉伯半乳聚糖和酚，其可以从木材例如西部落叶松和Tamarack树品种分离。 除了从木材中回收有机化合物之外，纤维木制品也可以分离成干净纤维的形式，例如可以用作木材加工应用中的原料或用于制造高品质纸制品 。 在一个实施方案中，首先将纤维状植物材料压缩，以回收液体渗出物和第一受压植物纤维产品。 任选地，基本上没有任何添加的溶剂，纤维状植物材料如木颗粒被压缩，以产生纯正常液体渗出物和第一压制植物产品。 然后可以用例如水性溶剂浸渍第一植物纤维产品，以回收提取液和浸渍的植物纤维。 然后将浸渍的植物纤维压缩以回收液体压制物和第二压制纤维产品。 使用这些方法，在一个实施方案中，基本上纯的阿拉伯半乳聚糖渗出物和木纤维产物可以通过酚的最小共萃取从落叶松的木材中回收。 另外，各种不同的植物代谢物可以使用方法和装置从不同种类的木本植物中分离和/或鉴定。

公开(公告)号：US5641759A

公开(公告)日：1997-06-24

申请号：US66276

申请日：1993-05-26

申请人： John A. Patterson ,  Geoffrey N. Richards

发明人： John A. Patterson ,  Geoffrey N. Richards

IPC分类号： A23K1/16 ,  A23K1/18 ,  A01N43/04 ,  A23C17/00 ,  A61K31/715

CPC分类号： A23K50/75 ,  A23K20/163 ,  Y10S426/801 ,  Y10S514/867

摘要： The present invention relates to a method and composition for animal husbandry comprising administering to livestock and other animals at least one composition selected from the group consisting of a caramel composition comprising a high content of fructose oligosaccharides, termed sucrose thermal oligosaccharides (STO), and a product comprising sucrose thermal kestoses. The growth of livestock and other animals may be greatly increased by administering STO caramel or sucrose thermal kestoses. The compositions alter specific microflora within the gastrointestinal tract to enhance the health of the animal by increasing the numbers of bifidobacteria and lactobacilli, and decreasing the numbers of undesirable microorganisms.

摘要翻译： 本发明涉及一种用于畜牧业的方法和组合物，其包括向家畜和其他动物施用至少一种选自由高含量的果糖寡糖（称为蔗糖热寡糖（STO））组成的组的焦糖组合物，和 产品包括蔗糖热esto。。 通过施用STO焦糖或蔗糖热esto，可以大大增加家畜和其他动物的生长。 组合物通过增加双歧杆菌和乳杆菌的数量以及减少不期望的微生物的数量来改变胃肠道内的特异性微生物群落以增强动物的健康。

公开(公告)号：US5206355A

公开(公告)日：1993-04-27

申请号：US855355

申请日：1992-03-19

申请人： Geoffrey N. Richards ,  Merilyn Manley-Harris

发明人： Geoffrey N. Richards ,  Merilyn Manley-Harris

IPC分类号： A23K1/16 ,  A23L1/236 ,  A23L1/308 ,  C07H3/06 ,  C08B37/00

CPC分类号： C07H3/06 ,  A23K20/163 ,  A23L27/33 ,  A23L33/26 ,  C08B37/006 ,  Y10S127/01

摘要： Sucrose is treated with an acid catalyst to form an amorphous sucrose anhydrous melt. Heating of the anhydrous melt at 80.degree.-100.degree. C. forms three known kestoses and the novel products, viz. .alpha.-fructosylsucrose anomers of 6-kestose, neokestose, and 1-kestose. Heating of the anhydrous melt at 125.degree.-175.degree. C. produces a fructoglucan sucrose polymer having a molecular weight of about 2,000 to 10,000 Daltons. All of these products are useful as sweeteners, food additives, additives for animal food, and bulking agents.

摘要翻译： 蔗糖用酸催化剂处理以形成无定形蔗糖无水熔体。 在80°-100℃下加热无水熔融物形成三种已知的kesto和新产物， 6-kestose，neokestose和1-kestose的α-果糖基蔗糖端基异构体。 在125-175℃下加热无水熔体，产生分子量约为2,000至10,000道尔顿的果糖葡聚糖蔗糖聚合物。 所有这些产品都可用作甜味剂，食品添加剂，动物食品添加剂和填充剂。

公开(公告)号：US06258796B1

公开(公告)日：2001-07-10

申请号：US09174232

申请日：1998-10-16

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A61K31715

CPC分类号： C08B37/006 ,  A61K47/61

摘要： Arabinogalactan compositions are provided which are useful in a wide variety of different biomedical applications. In one embodiment, water soluble lipidated arabinogalactans are provided which include arabinogalactan with a limited proportion of lipophilic groups, such as long-chain hydrocarbon groups, covalently attached to free hydroxyl groups on the arabinogalactan. The lipidated arabinogalactans are water soluble and biocompatible and are useful for a wide variety of different biomedical applications. The lipidated arabinogalactans can be used, for example, to inhibit cell adhesion, and to inhibit infection or inflammation. The lipidated arabinogalactans further may be used as adjuvants, to inhibit metastasis, and in other therapeutic applications.

摘要翻译： 提供了可用于各种不同生物医学应用的阿拉伯半乳聚糖组合物。 在一个实施方案中，提供了水溶性脂质化的阿拉伯半乳聚糖，其包括与阿拉伯半乳聚糖共价连接到游离羟基上的有限比例的亲脂基团如长链烃基的阿拉伯半乳聚糖。 脂质化的阿拉伯半乳聚糖是水溶性和生物相容性的，并且可用于各种不同的生物医学应用。 脂质阿拉伯半乳聚糖可用于例如抑制细胞粘附，并抑制感染或炎症。 脂质化的阿拉伯半乳聚糖进一步可用作佐剂，抑制转移和其它治疗应用。

公开(公告)号：US6087092A

公开(公告)日：2000-07-11

申请号：US356759

申请日：1999-07-19

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A61K31/717 ,  A61K45/06 ,  C12Q1/00 ,  C07G17/00 ,  C12N1/20

CPC分类号： A61K45/06 ,  A61K31/717 ,  Y10S514/867

摘要： Compositions containing hemicelluloses in combination with polyphenols, methods of preparing the compositions, and methods of treating humans or animals with the composition are provided. Also provided is a method for increasing growth rate, improving feed efficiency and decreasing scour after weaning in an animal by administering an effective amount of the composition to the animal. The hemicelluloses preferably are not consumed by human alimentary enzymes or harmful bacteria, such as putrefactive or pathogenic bacteria, in the gastrointestinal tract, and are consumed by beneficial bacteria, such as bifidobacteria, in the gastrointestinal tract. The polyphenols preferably decrease the amount of harmful bacteria in the gastrointestinal tract. The compositions can optionally contain a carrier or be used as a feed addition and are administered to humans or other animals in an amount sufficient to treat the gastrointestinal disorder.

摘要翻译： 提供了含有与多酚组合的半纤维素的组合物，制备组合物的方法以及用该组合物治疗人或动物的方法。 还提供了一种通过向动物施用有效量的组合物来增加生长速度，提高饲料效率和减少在动物中断奶后的冲洗的方法。 半纤维素优选在消化道中不被人类消化酶或有害细菌（例如腐败性或致病性细菌）消耗，并且在胃肠道中被有益细菌例如双歧杆菌消耗。 多酚优选减少胃肠道中有害细菌的量。 组合物可任选地含有载体或用作添加剂，并以足以治疗胃肠道疾病的量施用于人或其他动物。

公开(公告)号：US5614501A

公开(公告)日：1997-03-25

申请号：US434492

申请日：1995-05-04

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A61K31/717 ,  A61K45/06 ,  A61K31/70 ,  A61K31/715

CPC分类号： A61K45/06 ,  A61K31/717 ,  Y10S514/867

摘要： Compositions containing hemicelluloses in combination with polyphenols, methods of preparing the compositions, and methods of treating humans or animals with the composition are provided. Also provided is a method for increasing growth rate, improving feed efficiency and decreasing scour after weaning in an animal by administering an effective amount of the composition to the animal. The hemicelluloses preferably are not consumed by human alimentary enzymes or harmful bacteria, such as putrefactive or pathogenic bacteria, in the gastrointestinal tract, and are consumed by beneficial bacteria, such as bifidobacteria, in the gastrointestinal tract. The polyphenols preferably decrease the amount of harmful bacteria in the gastrointestinal tract. The compositions can optionally contain a carrier or be used as a feed addition and are administered to humans or other animals in an amount sufficient to treat the gastrointestinal disorder.

摘要翻译： 提供了含有与多酚组合的半纤维素的组合物，制备组合物的方法以及用该组合物治疗人或动物的方法。 还提供了一种通过向动物施用有效量的组合物来增加生长速度，提高饲料效率和减少在动物中断奶后的冲洗的方法。 半纤维素优选在消化道中不被人类消化酶或有害细菌（例如腐败性或致病性细菌）消耗，并且在胃肠道中被有益细菌例如双歧杆菌消耗。 多酚优选减少胃肠道中有害细菌的量。 组合物可任选地含有载体或用作添加剂，并以足以治疗胃肠道疾病的量施用于人或其他动物。

公开(公告)号：US5439893A

公开(公告)日：1995-08-08

申请号：US66843

申请日：1993-05-26

申请人： Geoffrey N. Richards ,  Carolyn E. Campbell

发明人： Geoffrey N. Richards ,  Carolyn E. Campbell

IPC分类号： A23L1/09 ,  A23L1/308 ,  A61K31/70 ,  A61K31/715 ,  C08B37/00

CPC分类号： A61K31/715 ,  A23L29/30 ,  A23L33/26 ,  A61K31/70 ,  Y10S426/801 ,  Y10S514/867

摘要： The present invention relates to a method for the treatment and prevention of diarrhea comprising administering to humans a sugar selected from the group consisting of a caramel composition comprising a high content of fructose oligosaccharides, termed sucrose thermal oligosaccharides (STO), a composition comprising sucrose thermal kestoses, and fructoglucan polymers. The sugars are a natural product and greatly speed recovery from diarrhea and reduce the recurrence of diarrhea.

摘要翻译： 本发明涉及一种治疗和预防腹泻的方法，包括向人类施用选自由含有高含量果糖寡糖（称为蔗糖热寡糖（STO））的焦糖组合物组成的组的糖，包含蔗糖热 kestoses和果糖聚糖。 糖是一种天然产物，可大大加速腹泻恢复，减少腹泻复发。

公开(公告)号：US5318794A

公开(公告)日：1994-06-07

申请号：US983446

申请日：1992-12-02

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A23G3/32 ,  C08B30/00 ,  A23L1/22

CPC分类号： A23G3/32 ,  Y10S127/01

摘要： A method for producing caramel having a high content of fructose oligosaccharides and caramel product produced thereby is disclosed which comprises mixing sucrose and an organic acid in a ball mill for approximately 0.5 to 4 hours, heating to a temperature of 130.degree.-160.degree. C. for 0.5 to 15 minutes and cooling quickly to produce a caramel product. The ball milling reduces crystallinity and intimately mixes the sucrose and organic acid, lowering the thermolization temperature. The product contains a high proportion of fructose oligosaccharides (D.P. .about.3-10).

摘要翻译： 公开了一种生产具有高果糖低聚糖焦糖产生焦糖的方法，该方法包括将蔗糖与有机酸在球磨机中混合约0.5-4小时，加热至130-116℃。 持续0.5至15分钟，并快速冷却以产生焦糖产品。 球磨可降低结晶度，并将蔗糖和有机酸紧密混合，降低热溶温度。 该产品含有高比例的果糖低聚糖（D.P.DIFIFERENCE 3-10）。

公开(公告)号：US06303584B1

公开(公告)日：2001-10-16

申请号：US08754225

申请日：1996-11-20

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A61K31715

CPC分类号： C08B37/006 ,  A61K47/61

摘要： Arabinogalactan compositions are provided which are useful in a wide variety of different biomedical applications. In one embodiment, water soluble lipidated arabinogalactans are provided which include arabinogalactan with a limited proportion of lipophilic groups, such as long-chain hydrocarbon groups, covalently attached to free hydroxyl groups on the arabinogalactan. The lipidated arabinogalactans are water soluble and biocompatible and are useful for a wide variety of different biomedical applications. The lipidated arabinogalactans can be used, for example, to inhibit cell adhesion, and to inhibit infection or inflammation. The lipidated arabinogalactans further may be used as adjuvants, to inhibit metastasis, and in other therapeutic applications.

公开(公告)号：US06210678B1

公开(公告)日：2001-04-03

申请号：US09159902

申请日：1998-09-24

申请人： Geoffrey N. Richards

发明人： Geoffrey N. Richards

IPC分类号： A21D400

CPC分类号： A23L3/3463 ,  A23L3/3472 ,  A23L3/349 ,  A23L3/3544

摘要： A composition is provided for reducing bacterial growth in food products. The composition includes a wood extract containing polyphenols and may contain arabinogalactan. The composition suppresses or prevents the growth of E. coli and of Salmonella sp. The wood extract imparts little or no residual taste to the food product. However, it can readily be removed if desired by washing before use of the food. The composition may be essentially arabinogalactan-free to further reduce bacterial growth.

摘要翻译： 提供用于减少食品中的细菌生长的组合物。 该组合物包括含有多酚的木材提取物，并且可以含有阿拉伯半乳聚糖。 该组合物抑制或阻止大肠杆菌和沙门氏菌的生长。 木材提取物对食品很少或没有残留的味道。 然而，如果需要，可以在使用食物之前通过洗涤容易地去除它。 组合物可以基本上是阿拉伯半乳聚糖，以进一步减少细菌生长。