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1.发明授权Dose setting element for a drug delivery device and drug delivery device with dose setting element 有权用于具有剂量设定元件的药物递送装置和药物递送装置的剂量设定元件公开(公告)号：US08864720B2
公开(公告)日：2014-10-21
申请号：US13139684
申请日：2009-12-17
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
摘要翻译： 本发明涉及一种用于药物输送装置（2）的剂量设定机构（1），其包括多个单独的剂量设定元件（3.1至3.n），其中设定剂量体积和/或剂量数量 通过将各个剂量设定元件（3.1至3.n）中的至少一个从堆叠位置（I）移动到初始位置（II），并且其中通过移动至少一个剂量设定元件（ 3.1至3.n）从初始位置（II）到分配位置（III），并且其中剂量设定元件（3.1至3.n）从初始位置（II）到分配位置（III）的移动 在初始位置（II）中受到剂量设定元件（3.1至3.n）的至少高度（h）的限制，其中每个剂量设定元件（3.1至3.n）包括多个凸起（B1至 Bm）在至少一个表面侧（S1），其中每个剂量设定元件（3.1至3.n）的高度（h）等于剂量设定元件（3.1至3.n）的厚度（D） 3.n）和凸起高度（h1）。
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2.发明申请Dose Setting Element for a Drug Delivery Device and Drug Delivery Device with Dose Setting Element 有权用于药物输送装置的药物设定元件和具有剂量设定元件的药物输送装置公开(公告)号：US20120103328A1
公开(公告)日：2012-05-03
申请号：US13139684
申请日：2009-12-17
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
摘要翻译： 本发明涉及一种用于药物输送装置（2）的剂量设定机构（1），其包括多个单独的剂量设定元件（3.1至3.n），其中设定剂量体积和/或剂量数量 通过将各个剂量设定元件（3.1至3.n）中的至少一个从堆叠位置（I）移动到初始位置（II），并且其中通过移动至少一个剂量设定元件（ 3.1至3.n）从初始位置（II）到分配位置（III），并且其中剂量设定元件（3.1至3.n）从初始位置（II）到分配位置（III）的移动 在初始位置（II）中受到剂量设定元件（3.1至3.n）的至少高度（h）的限制，其中每个剂量设定元件（3.1至3.n）包括多个凸起（B1至 Bm）在至少一个表面侧（S1），其中每个剂量设定元件（3.1至3.n）的高度（h）等于剂量设定元件（3.1至3.n）的厚度（D） 3.n）和凸起高度（h1）。
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公开(公告)号：US09669170B2
公开(公告)日：2017-06-06
申请号：US14241842
申请日：2012-09-11
申请人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , Carl Tucker
发明人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , Carl Tucker
CPC分类号： A61M5/326 , A61M5/28 , A61M2005/3247
摘要： A safety device suitable for a pre-filled syringe containing a medicament includes a chassis adapted to be affixed to the pre-filled syringe, a deformable flexible outer structure made from a material with a shape memory, and a substantially cylindrical needle shield affixed or integral to the outer structure. The deformed flexible outer structure is capable of advancing the needle shield with respect to the chassis in a distal direction into a position in which the needle shield projects from the chassis in the distal direction. A biasing force for advancing the needle shield originates from a shape memory effect that causes the deformed flexible outer structure to substantially return to its unstressed shape.
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公开(公告)号：US20140213983A1
公开(公告)日：2014-07-31
申请号：US14241842
申请日：2012-09-11
申请人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , Carl Tucker
发明人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , Carl Tucker
IPC分类号： A61M5/32
CPC分类号： A61M5/326 , A61M5/28 , A61M2005/3247
摘要： According to the invention, a safety device suitable (S) for a pre-filled syringe containing a medicament comprises a chassis adapted to be affixed to the pre-filled syringe, a deformable flexible outer structure made from a material with a shape memory and a substantially cylindrical needle shield affixed or integral to the outer structure. The deformed flexible outer structure is capable of advancing the needle shield with respect to the chassis in a distal direction (D) into a position in which the needle shield projects from the chassis in the distal direction (D). A biasing force for advancing the needle shield originates from a shape memory effect that causes the deformed flexible outer structure to substantially return to its unstressed shape.
摘要翻译： 根据本发明，一种用于装有药物的预装注射器的适于（S）的安全装置包括适于固定到预填充注射器的底盘，由具有形状记忆的材料制成的可变形柔性外部结构， 基本上圆柱形的针护罩固定或与外部结构一体。 变形的柔性外部结构能够使针护罩相对于底盘沿远端方向（D）推进到针护罩在远端方向（D）处从底盘突出的位置。 用于推进针护罩的偏置力源自形状记忆效应，其使得变形的柔性外部结构基本上返回到其不受应力的形状。
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公开(公告)号：US20140114243A1
公开(公告)日：2014-04-24
申请号：US14009506
申请日：2012-04-11
IPC分类号： A61F9/00
CPC分类号： A61F9/0026 , A61F9/0017
摘要： Described is a device for intraocular injection comprising a drug delivery device, a foot at a distal end of the drug delivery device for positioning the drug delivery device with respect to an injection site, and a magnifying device coupled to one of the drug delivery device and the foot for magnifying a view of the injection site.
摘要翻译： 描述了一种用于眼内注射的装置，其包括药物递送装置，用于相对于注射部位定位药物递送装置的药物递送装置的远端处的脚，以及耦合到药物递送装置和药物递送装置之一的放大装置， 用于放大注射部位视图的脚。
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公开(公告)号：US20140012208A1
公开(公告)日：2014-01-09
申请号：US14005879
申请日：2012-03-22
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/3146 , A61M5/31543 , A61M5/31573 , A61M2005/2488 , A61M2005/3142 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drug delivery device is provided comprising a body, a cartridge holder for receiving a cartridge, and means for releasably coupling the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.
摘要翻译： 提供了一种可重置的药物输送装置，其包括主体，用于接收药筒的药筒保持器和用于将药筒保持器可释放地联接到身体或剂量设定机构的装置。 在盒保持器相对于身体或剂量设定机构的初始旋转联接运动期间，使盒保持器相对于身体或剂量设定机构在第一轴向方向上移动，并且在盒的持续旋转联接运动期间 保持器相对于身体或剂量设定机构使药筒保持器在第二相反轴向方向上移动。
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公开(公告)号：US20130218096A1
公开(公告)日：2013-08-22
申请号：US13516255
申请日：2010-12-16
IPC分类号： A61M5/315
CPC分类号： A61M5/31535 , A61M5/168 , A61M5/31525 , A61M5/31551 , A61M5/31561 , A61M2005/3154
摘要： A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10′, 10″, 10″′) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).
摘要翻译： 提供了用于药物递送装置的剂量设定机构，其包括在药物递送装置的第一组分部分（2）上的第一最大剂量停止特征（1）和在第二组分部分（4）上的相应的第二最大剂量停止特征（3） ），其中第一和第二最大剂量停止特征（1,3）被设计成限制第一和第二组成部分（2,4）之间的相对运动。 为了限制可以选择的最大剂量，在第一和第二最大剂量之间插入第一组分部分（2）上设置最大剂量限制装置（5,10,10'，10“，10”） 停止功能（1，3）。
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公开(公告)号：US20130197447A1
公开(公告)日：2013-08-01
申请号：US13576307
申请日：2011-02-15
IPC分类号： A61M5/19
CPC分类号： A61M5/19 , A61M5/20 , A61M5/24 , A61M5/31543 , A61M5/31553 , A61M5/3156 , A61M5/31561 , A61M5/31583 , A61M5/31593 , A61M2005/2407
摘要： A semi-automatic injection device (12) is disclosed containing two reservoirs (6) of medicament, where a trigger (11) controls the unwinding of two torsional springs (18) to cause simultaneous injection of medicament from each reservoir through a needle adaptor configured with a 2 to 1 needle cannula arrangement.
摘要翻译： 公开了一种半自动注射装置（12），其包含两个药物储存器（6），其中触发器（11）控制两个扭转弹簧（18）的展开，以引起来自每个储存器的药物同时从配置的针头适配器 具有2到1针插管安排。
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公开(公告)号：US20130190697A1
公开(公告)日：2013-07-25
申请号：US13702808
申请日：2011-06-09
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation member being adapted to move the stop member and the drive member in the distal direction with respect to the housing when the normal operation state is switched to the reset state, thereby decoupling the stop member and the drive member and decoupling the drive member and the rotation member.
摘要翻译： 用于可在正常操作状态和复位状态之间切换的药物输送装置的驱动机构包括具有近端和远端的壳体，适于沿第一方向旋转的旋转构件 方向相对于壳体，驱动构件，其中在正常操作状态下，旋转构件与驱动构件联接，使得驱动构件沿第二方向旋转构件的旋转运动，活塞杆，其中在 当驱动构件相对于壳体沿第二方向旋转时，活塞杆相对于壳体在远端方向上移位，其中在正常操作状态下，止动构件与驱动器联接 使得止动构件防止驱动构件相对于壳体沿第一方向的旋转运动，以及用于切换操作的分离构件 n状态，当正常操作状态切换到复位状态时，分离构件适于在远端方向上相对于壳体移动止动构件和驱动构件，从而使止动构件和驱动构件分离， 驱动构件和旋转构件。
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公开(公告)号：US20100012562A1
公开(公告)日：2010-01-21
申请号：US12173960
申请日：2008-07-16
IPC分类号： E04H4/16
CPC分类号： F04D29/706 , Y10S55/17
摘要： A turbomachine includes a compressor portion having an intake and a filtration system having an interior and an exterior. The filtration system is arranged upstream of the intake and includes a drain capable of fluid communication with the exterior of the filtration system. The drain includes a one-way valve that allows liquid separated from air flowing through the interior of the filtration system to pass through the drain to the exterior of the filtration system in a first direction, and substantially limits a flow of unfiltered air from entering the intake from the exterior in a second direction.
摘要翻译： 涡轮机包括具有入口的压缩机部分和具有内部和外部的过滤系统。 过滤系统布置在进气口的上游，并且包括能够与过滤系统的外部流体连通的排水口。 排水管包括单向阀，其允许从流过过滤系统内部的空气分离的液体沿着第一方向通过排水口到过滤系统的外部，并且基本上限制未过滤空气的流入进入 从外部进入第二个方向。
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