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公开(公告)号：US20080248589A1
公开(公告)日：2008-10-09
申请号：US11596285
申请日：2005-05-19
申请人： Christopher M. Belisle , John A. Walker , Sarah M. Ngola , Douglas P. Greiner , Mark J. Levy , Xiaoxia Zhao , Irene Y. Chen , Mark L. Stolowitz , Donald P. Paquin
发明人： Christopher M. Belisle , John A. Walker , Sarah M. Ngola , Douglas P. Greiner , Mark J. Levy , Xiaoxia Zhao , Irene Y. Chen , Mark L. Stolowitz , Donald P. Paquin
IPC分类号： G01N33/543 , B01J19/00
CPC分类号： B01L3/5085 , B01L3/502707 , B01L3/502792 , B01L3/5088 , B01L2200/12 , B01L2300/087 , B01L2300/089 , B82Y15/00 , B82Y30/00 , C23C26/00 , C23C30/00 , Y10T436/24 , Y10T436/25
摘要： The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
摘要翻译： 本发明涉及可用于执行分析测量的样本呈现装置。 这些装置已被配置成能够实现液体处理的各个方面，例如：保留，储存，运输，集中，定位和转移。 此外，这些设备可以增强分析物的检测和表征。 本发明的样品展示装置由具有不同润湿性的多个区域的一个或多个基材组成。 公开了使用本发明的样品呈现装置分析样品的方法以及制备样品显示装置的方法。
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公开(公告)号：US20110070659A1
公开(公告)日：2011-03-24
申请号：US12786133
申请日：2010-05-24
申请人： Christopher M. Belisle , John A. Walker, II , Sarah M. Ngola , Douglas P. Greiner , Mark J. Levy , Xiaoxia Zhao , Irene Y. Chen , Mark L. Stolowitz , Donald P. Paquin
发明人： Christopher M. Belisle , John A. Walker, II , Sarah M. Ngola , Douglas P. Greiner , Mark J. Levy , Xiaoxia Zhao , Irene Y. Chen , Mark L. Stolowitz , Donald P. Paquin
IPC分类号： G01N33/543 , G01N1/00 , G01N33/50 , B01L9/00 , G01N21/00 , G01N21/76 , G01N24/00 , G01N30/96
CPC分类号： B01L3/5085 , B01L3/502707 , B01L3/502792 , B01L3/5088 , B01L2200/12 , B01L2300/087 , B01L2300/089 , B82Y15/00 , B82Y30/00 , C23C26/00 , C23C30/00 , Y10T436/24 , Y10T436/25
摘要： The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
摘要翻译： 本发明涉及可用于执行分析测量的样本呈现装置。 这些装置已被配置成能够实现液体处理的各个方面，例如：保留，储存，运输，集中，定位和转移。 此外，这些设备可以增强分析物的检测和表征。 本发明的样品展示装置由具有不同润湿性的多个区域的一个或多个基材组成。 公开了使用本发明的样品呈现装置分析样品的方法，以及制备样品显示装置的方法。
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公开(公告)号：US20050164402A1
公开(公告)日：2005-07-28
申请号：US11036707
申请日：2005-01-13
申请人： Christopher Belisle , John Walker , Sarah Ngola , Douglas Greiner , Mark Levy , Xiaoxia Zhao , Irene Chen , Mark Stolowitz , Donald Paquin
发明人： Christopher Belisle , John Walker , Sarah Ngola , Douglas Greiner , Mark Levy , Xiaoxia Zhao , Irene Chen , Mark Stolowitz , Donald Paquin
CPC分类号： B01L3/5085 , B01L3/502707 , B01L3/502792 , B01L3/5088 , B01L2200/12 , B01L2300/087 , B01L2300/089 , B82Y15/00 , B82Y30/00 , C23C26/00 , C23C30/00 , Y10T436/24 , Y10T436/25
摘要： The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
摘要翻译： 本发明涉及可用于执行分析测量的样本呈现装置。 这些装置已被配置成能够实现液体处理的各个方面，例如：保留，储存，运输，集中，定位和转移。 此外，这些设备可以增强分析物的检测和表征。 本发明的样品展示装置由具有不同润湿性的多个区域的一个或多个基材组成。 公开了使用本发明的样品呈现装置分析样品的方法，以及制备样品显示装置的方法。
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公开(公告)号：US20070016980A1
公开(公告)日：2007-01-18
申请号：US11533381
申请日：2006-09-20
申请人： L. Lyznik , Xiaoxia Zhao , Isabelle Coats , William Gordon-Kamm
发明人： L. Lyznik , Xiaoxia Zhao , Isabelle Coats , William Gordon-Kamm
CPC分类号： C12N15/8213 , C12N9/00
摘要： The invention provides novel methods of gene targeting using replication in order to increase the efficiency of targeted genetic modification in an eukaryotic organism. Included are vectors, expression cassettes, and modified cells, plants and seeds.
摘要翻译： 本发明提供使用复制的基因靶向的新方法，以提高真核生物体中靶向遗传修饰的效率。 包括载体，表达盒和修饰的细胞，植物和种子。
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公开(公告)号：US07608752B2
公开(公告)日：2009-10-27
申请号：US11533381
申请日：2006-09-20
CPC分类号： C12N15/8213 , C12N9/00
摘要： The invention provides novel methods of gene targeting using replication in order to increase the efficiency of targeted genetic modification in an eukaryotic organism. Included are vectors, expression cassettes, and modified cells, plants and seeds.
摘要翻译： 本发明提供使用复制的基因靶向的新方法，以提高真核生物体中靶向遗传修饰的效率。 包括载体，表达盒和修饰的细胞，植物和种子。
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公开(公告)号：US07164056B2
公开(公告)日：2007-01-16
申请号：US10138546
申请日：2002-05-03
CPC分类号： C12N15/8213 , C12N9/00
摘要： The invention provides novel methods of gene targeting using replication in order to increase the efficiency of targeted genetic modification in an eukaryotic organism. Included are vectors, expression cassettes, and modified cells, plants and seeds.
摘要翻译： 本发明提供使用复制的基因靶向的新方法，以提高真核生物体中靶向遗传修饰的效率。 包括载体，表达盒和修饰的细胞，植物和种子。
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