摘要:
The present invention provides methods for using the level of caspase 3 activity for determining or prognosticating likelihood of cancer recurrence or relapse in a patient after the treatment for cancer. The present invention also provides methods for treating cancer in a patient using a caspase 3 inhibitor in conjunction with a conventional cancer treatment.
摘要:
A method for controlling in vivo heat-inducible gene expression for provision of therapeutic polypeptide. The method includes the steps of: (a) providing a construct comprising a polynucleotide encoding a therapeutic polypeptide, wherein the polynucleotide is operatively linked to a heat-inducible promoter; (b) administering the construct to a warm-blooded vertebrate at a site at or near the tumor; and (c) applying heat to the site at or near the tumor to express the therapeutic polypeptide, whereby anti-tumor activity is observed.
摘要:
The presently claimed subject matter provides conditionally replication competent adenoviral vectors that confer selective cytotoxicity on cells expressing HIF-1 by infecting cells that allow HIF-1 inducible promoters present within the vectors to function. Also provided are compositions and host cells based upon the vectors, as well as methods of propagating and using the vectors. The presently claimed subject matter further provides a method of inhibiting tumor growth by co-infecting cells in a tumor with a conditionally replication competent adenovirus vector in conjunction with a replication deficient adenovirus vector.
摘要:
The presently claimed subject matter provides conditionally replication competent adenoviral vectors that confer selective cytotoxicity on cells expressing HIF-1 by infecting cells that allow HIF-1 inducible promoters present within the vectors to function. Also provided are compositions and host cells based upon the vectors, as well as methods of propagating and using the vectors. The presently claimed subject matter further provides a method of inhibiting tumor growth by co-infecting cells in a tumor with a conditionally replication competent adenovirus vector in conjunction with a replication deficient adenovirus vector.
摘要:
A method for controlling in vivo heat-inducible gene expression for provision of therapeutic polypeptide. The method includes the steps of: (a) providing a construct comprising a polynucleotide encoding a therapeutic polypeptide, wherein the polynucleotide is operatively linked to a heat-inducible promoter; (b) administering the construct to a warm-blooded vertebrate at a site at or near the tumor; and (c) applying heat to the site at or near the tumor to express the therapeutic polypeptide, whereby anti-tumor activity is observed.
摘要:
A method and apparatus for deblocking of reconstructed video are disclosed. In one embodiment, the method divides a block boundary into two sub-boundaries and separates lines or column across the sub-boundaries into two groups. The deblocking filter decision for each group is determined based on the lines or columns in the respective group. In another embodiment, the method divides block edges of blocks in the LCUs into two edge groups, where the first edge group corresponds to horizontal block edges between two LCUs and the second edge group corresponds to remaining block edges not included in the first edge group. The number of lines processed by a vertical filter in the first edge group is less than the number of lines processed by a vertical filter in the second edge group. Accordingly, a system embodying the present invention has reduced storage requirement.
摘要:
A task management system including a monitor and a processing unit is provided. The monitor is for displaying a task schedule, which sequentially tabulates multiple time spots and multiple corresponding tasks. The processing unit is for operating an object at a to-be-executed time spot when the object is dragged to the to-be-executed time spot of the task schedule.
摘要:
Systems and methods for describing video content establish video description records which include an object set (24), an object hierarchy (26) and entity relation graphs (28). Video objects can include global objects, segment objects and local objects. The video objects are further defined by a number of features organized in classes, which in turn are further defined by a number of feature descriptors (36, 38, and 40). The relationships (44) between and among the objects in the object set (24) are defined by the object hierarchy (26) and entity relation graphs (28). The video description records provide a standard vehicle for describing the content and context of video information for subsequent access and processing by computer applications such as search engines, filters and archive systems.
摘要:
The invention provides a system and method for integrating multimedia descriptions in a way that allows humans, software components or devices to easily identify, represent, manage, retrieve, and categorize the multimedia content. In this manner, a user who may be interested in locating a specific piece of multimedia content from a database, Internet, or broadcast media, for example, may search for and find the multimedia content. In this regard, the invention provides a system and method that receives multimedia content and separates the multimedia content into separate components which are assigned to multimedia categories, such as image, video, audio, synthetic and text. Within each of the multimedia categories, the multimedia content is classified and descriptions of the multimedia content are generated. The descriptions are then formatted, integrated, using a multimedia integration description scheme, and the multimedia integration description is generated for the multimedia content. The multimedia description is then stored into a database. As a result, a user may query a search engine which then retrieves the multimedia content from the database whose integration description matches the query criteria specified by the user. The search engine can then provide the user a useful search result based on the multimedia integration description.
摘要:
A system and method for determining the magnetic sensitivity of a Hall-effect switch through the use of a variable powered DC electromagnet having a permanent magnet attached to it. In use the electromagnet is placed in contact with a Hall-effect switch component and the DC voltage varied until a detector determines the Hall-effect switch has been triggered. The electromagnet is then moved to be in contact with a probe connected to a Gauss meter to determine the magnetic sensitivity of the Hall-effect switch.