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1.发明申请MURINE ZCYTOR17 LIGAND POLYPEPTIDES AND POLYNUCLEOTIDES 有权MURINE ZCYTOR17 LIGAND POLYPEPTIDES和POLYNUCLEOTIDES公开(公告)号：US20070077627A1
公开(公告)日：2007-04-05
申请号：US11610126
申请日：2006-12-13
申请人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
发明人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
CPC分类号： C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
摘要： The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
摘要翻译： 本发明涉及zcytor17lig多核苷酸，多肽和抗zcytor17抗体分子。 zcytor17lig是一种新型细胞因子。 多肽可用于刺激免疫系统的方法，体外和体内造血细胞的增殖和/或发育。 本发明还包括生产蛋白质的方法，用途及其抗体。
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公开(公告)号：US20070048834A1
公开(公告)日：2007-03-01
申请号：US11552710
申请日：2006-10-25
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
IPC分类号： C12P21/06 , C07H21/04 , C07K14/715
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
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公开(公告)号：US20070048835A1
公开(公告)日：2007-03-01
申请号：US11552721
申请日：2006-10-25
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
IPC分类号： C12P21/06 , C07H21/04 , C07K14/715
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
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公开(公告)号：US20070048833A1
公开(公告)日：2007-03-01
申请号：US11552688
申请日：2006-10-25
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
IPC分类号： C07K14/715 , C07H21/04 , C12P21/06
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
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公开(公告)号：US20070048223A1
公开(公告)日：2007-03-01
申请号：US11553835
申请日：2006-10-27
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
IPC分类号： A61K51/00 , A61K39/395 , C07K16/28 , C07K16/46
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
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公开(公告)号：US20070111266A1
公开(公告)日：2007-05-17
申请号：US11613091
申请日：2006-12-19
申请人： CINDY SPRECHER , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
发明人： CINDY SPRECHER , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
IPC分类号： G01N33/567 , C07K16/24 , C07K16/28
CPC分类号： C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
摘要： The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
摘要翻译： 本发明涉及zcytor17lig多核苷酸，多肽和抗zcytor17抗体分子。 zcytor17lig是一种新型细胞因子。 多肽可用于刺激免疫系统的方法，体外和体内造血细胞的增殖和/或发育。 本发明还包括生产蛋白质的方法，用途及其抗体。
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公开(公告)号：US20060141579A1
公开(公告)日：2006-06-29
申请号：US11301764
申请日：2005-12-13
申请人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
CPC分类号： C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
摘要： The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
摘要翻译： 本发明涉及zcytor17lig多核苷酸，多肽和抗zcytor17抗体分子。 zcytor17lig是一种新型细胞因子。 多肽可用于刺激免疫系统的方法，体外和体内造血细胞的增殖和/或发育。 本发明还包括生产蛋白质的方法，用途及其抗体。
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8.发明申请CYTOKINE ZCYTOR17 LIGAND POLYPEPTIDES AND POLYNUCLEOTIDES 有权细胞因子ZCYTOR17 LIGAND POLYPEPTIDES和POLYNUCLEOTIDES公开(公告)号：US20070249020A1
公开(公告)日：2007-10-25
申请号：US11609499
申请日：2006-12-12
申请人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
发明人： Cindy Sprecher , Joseph Kuijper , Maria Dasovich , Francis Grant , Angela Hammond , Jane Gross
CPC分类号： C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
摘要： The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
摘要翻译： 本发明涉及zcytor17lig多核苷酸，多肽和抗zcytor17抗体分子。 zcytor17lig是一种新型细胞因子。 多肽可用于刺激免疫系统的方法，体外和体内造血细胞的增殖和/或发育。 本发明还包括生产蛋白质的方法，用途及其抗体。
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公开(公告)号：US20070140963A1
公开(公告)日：2007-06-21
申请号：US11553219
申请日：2006-10-26
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dillon
IPC分类号： A61K51/00 , A61K39/395 , A61K38/17
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
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公开(公告)号：US20070048832A1
公开(公告)日：2007-03-01
申请号：US11552647
申请日：2006-10-25
申请人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dollon
发明人： Cindy Sprecher , Zeren Gao , Joseph Kuijper , Maria Dasovich , Francis Grant , Scott Presnell , Theodore Whitmore , Angela Hammond , Julia Novak , Jane Gross , Stacey Dollon
IPC分类号： C12P21/06 , C07H21/04 , C07K14/715
CPC分类号： C07K16/2866 , A01K2217/05 , A61K38/00 , C07K14/52 , C07K14/715 , C07K2317/24 , C07K2317/76
摘要： Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
摘要翻译： 公开了新型多肽组合，编码多肽的多核苷酸以及相关组合物和方法，用于含有Zcytor17的多聚体或异二聚体细胞因子受体，其可用作新的细胞因子拮抗剂，并且用于检测刺激造血细胞增殖和/或发育的配体的方法 ，淋巴和骨髓细胞体外和体内。 本发明还包括用于产生多聚体或异二聚体细胞因子受体的方法，其用途及其抗体。
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