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1.发明授权公开(公告)号：US12064763B2
公开(公告)日：2024-08-20
申请号：US17770643
申请日：2020-10-21
发明人： Alex Dehgan , Paul Bunje , Hallie Holmes , David Baisch , Cifeng Fang , Gareth Fotouhi , Misa Winters , Sam Kelly , Brad Zamft
CPC分类号： B01L3/502715 , B01L3/5085 , B01L7/52 , G01N21/0332 , G01N21/253 , G01N33/53 , B01L2200/0684 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , G01N2035/00376
摘要： A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wells disposed outside the center region or radially disposed at or near a perimeter of the base portion; and (3) multiple connecting tracks that substantially linearly extend from a region at or proximate to the receiving area to the multiple reaction wells and designed to convey a sample including the target analyte from the receiving area to the multiple reaction wells, each of which are configured to transform the sample to a detectable sample.
Systems and methods of reacting and detecting the sample including the target analyte are also described.-
2.发明申请公开(公告)号：US20220250065A1
公开(公告)日：2022-08-11
申请号：US17725590
申请日：2022-04-21
发明人： Alex Dehgan , Paul Bunje , Hallie Holmes , David Baisch , Cifeng Fang , Gareth Fotouhi , Misa Winters , Sam Kelly , Brad Zamft
摘要： A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wells disposed outside the center region or radially disposed at or near a perimeter of the base portion; and (3) multiple connecting tracks that substantially linearly extend from a region at or proximate to the receiving area to the multiple reaction wells and designed to convey a sample including the target analyte from the receiving area to the multiple reaction wells, each of which are configured to transform the sample to a detectable sample.
Systems and methods of reacting and detecting the sample including the target analyte are also described.-
3.发明申请公开(公告)号：US20220347682A1
公开(公告)日：2022-11-03
申请号：US17770643
申请日：2020-10-21
发明人： Alex Dehgan , Paul Bunje , Hallie Holmes , David Baisch , Cifeng Fang , Gareth Fotouhi , Misa Winters , Sam Kelly , Brad Zamft
IPC分类号： B01L3/00
摘要： A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wells disposed outside the center region or radially disposed at or near a perimeter of the base portion; and (3) multiple connecting tracks that substantially linearly extend from a region at or proximate to the receiving area to the multiple reaction wells and designed to convey a sample including the target analyte from the receiving area to the multiple reaction wells, each of which are configured to transform the sample to a detectable sample. Systems and methods of reacting and detecting the sample including the target analyte are also described.
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4.发明申请公开(公告)号：US20220250064A1
公开(公告)日：2022-08-11
申请号：US17725583
申请日：2022-04-21
发明人： Alex Dehgan , Paul Bunje , Hallie Holmes , David Baisch , Cifeng Fang , Gareth Fotouhi , Misa Winters , Sam Kelly , Brad Zamft
摘要： A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wells disposed outside the center region or radially disposed at or near a perimeter of the base portion; and (3) multiple connecting tracks that substantially linearly extend from a region at or proximate to the receiving area to the multiple reaction wells and designed to convey a sample including the target analyte from the receiving area to the multiple reaction wells, each of which are configured to transform the sample to a detectable sample.
Systems and methods of reacting and detecting the sample including the target analyte are also described.-
5.发明授权公开(公告)号：US11311883B2
公开(公告)日：2022-04-26
申请号：US16758445
申请日：2018-10-23
IPC分类号： B01L3/00 , B01L7/00 , C12Q1/6844
摘要： Aniosotropic Ratchet Conveyor (“ARC”)-based biomolecule processing devices and related methods are described. The ARC-based biomolecule processing devices include (i) a substrate having an ARC track defined on or within the substrate and including a biomolecule receiving area, which is designed to receive biomolecule, and a reconstituting area, which is designed to contain dry reagents and is designed to receive a transport solution such that at the reconstituting area, dry reagents are reconstituted with transport solution; and (ii) a microheater area disposed at or near the biomolecule receiving area, fitted with a microheater, which is designed to heat biomolecule that is received through the biomolecule receiving area and designed to process heated biomolecule and dry reagents reconstituted with transport solution. The ARC track includes an arrangement of a plurality of hydrophilic rungs disposed on a hydrophobic region such that between consecutive hydrophobic rungs, a portion of the hydrophobic region is exposed.
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