公开(公告)号：US12124113B2

公开(公告)日：2024-10-22

申请号：US18114287

申请日：2023-02-27

Applicant: CooperVision International Limited ,  The University of Melbourne

Inventor： Laura Elizabeth Downie ,  David Charles Jackson ,  Algis Jonas Vingrys ,  Nancy J. Keir ,  Inna Maltseva

IPC: G02C7/04 ,  C07K16/24 ,  G01N33/68 ,  G02C7/02

CPC classification number: G02C7/047 ,  C07K16/244 ,  G01N33/6869 ,  G02C7/027 ,  G02C7/049 ,  G01N2333/54 ,  G01N2800/16

Abstract: Methods and devices to identify contact lens wearers predisposed to contact lens discomfort are described. The methods and devices involve obtaining a tear film sample from a person and determining an amount of interleukin-17A present in the tear film sample.

公开(公告)号：US12038556B2

公开(公告)日：2024-07-16

申请号：US18224082

申请日：2023-07-20

Applicant: CooperVision International Limited

Inventor： Inna Maltseva ,  Nancy J. Keir ,  Andrew Luk ,  Victoria Rogers

IPC: G02B1/04 ,  A45C11/00 ,  A61K9/00 ,  A61K31/355 ,  C08J3/075 ,  C08K5/1545

CPC classification number: G02B1/043 ,  A45C11/005 ,  A61K9/0051 ,  A61K31/355 ,  C08J3/075 ,  C08K5/1545 ,  C08J2333/26 ,  C08J2383/04

Abstract: A contact lens having antioxidant properties is described as well as methods of manufacturing the same. The contact lens can be present in a sealed contact lens package. The seal contact lens package can include at least a) a plastic base member having a cavity; b) a contact lens packaging solution in the cavity; c) a sterile, unworn contact lens immersed in the contact lens packaging solution in the cavity; and d) a cover that forms a liquid-tight seal with the plastic base member. As an example, the unworn contact lens is a silicone hydrogel contact lens having present therein vitamin E. The vitamin E is non-releasable from the unworn contact lens and the contact lens packaging solution has less than 1 ppm of vitamin E present. The vitamin E is trapped, embedded, absorbed, or non-covalently attached in the unworn contact lens.

公开(公告)号：US11754753B2

公开(公告)日：2023-09-12

申请号：US17228748

申请日：2021-04-13

Applicant: CooperVision International Limited

Inventor： Inna Maltseva ,  Nancy J. Keir ,  Andrew Luk ,  Victoria Rogers

IPC: G02B1/04 ,  A45C11/00 ,  A61K9/00 ,  A61K31/355 ,  C08J3/075 ,  C08K5/1545

CPC classification number: G02B1/043 ,  A45C11/005 ,  A61K9/0051 ,  A61K31/355 ,  C08J3/075 ,  C08K5/1545 ,  C08J2333/26 ,  C08J2383/04

Abstract: A contact lens having antioxidant properties is described as well as methods of manufacturing the same. The contact lens can be present in a sealed contact lens package. The seal contact lens package can include at least a) a plastic base member having a cavity; b) a contact lens packaging solution in the cavity; c) a sterile, unworn contact lens immersed in the contact lens packaging solution in the cavity; and d) a cover that forms a liquid-tight seal with the plastic base member. As an example, the unworn contact lens is a silicone hydrogel contact lens having present therein vitamin E. The vitamin E is non-releasable from the unworn contact lens and the contact lens packaging solution has less than 1 ppm of vitamin E present. The vitamin E is trapped, embedded, absorbed, or non-covalently attached in the unworn contact lens.

公开(公告)号：US12153288B2

公开(公告)日：2024-11-26

申请号：US18690276

申请日：2023-04-05

Applicant: CooperVision International Limited

Inventor： Erwin Si ,  Nancy Keir ,  Yuwen Liu ,  Inna Maltseva

IPC: G02C7/04 ,  B29D11/00 ,  G02B1/04

Abstract: A contact lens having an amount of at least one cooling agent and at least one TRPV1 inhibitor releasably adhered is described as well as method of manufacturing the same. The contact lens can be comfortably worn by contact lens wearers and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer and further can reduce or avoid any stinging/burning sensation when the contact lens is first used or a short time thereafter.

公开(公告)号：US20230244091A1

公开(公告)日：2023-08-03

申请号：US18114287

申请日：2023-02-27

Applicant: CooperVision International Limited ,  The University of Melbourne

Inventor： Laura Elizabeth Downie ,  David Charles Jackson ,  Algis Jonas Vingrys ,  Nancy J. Keir ,  Inna Maltseva

IPC: G02C7/04 ,  G02C7/02 ,  G01N33/68 ,  C07K16/24

CPC classification number: G02C7/047 ,  G02C7/027 ,  G02C7/049 ,  G01N33/6869 ,  C07K16/244 ,  G01N2800/16 ,  G01N2333/54

Abstract: Methods and devices to identify contact lens wearers predisposed to contact lens discomfort are described. The methods and devices involve obtaining a tear film sample from a person and determining an amount of interleukin-17A present in the tear film sample.

公开(公告)号：US11619832B2

公开(公告)日：2023-04-04

申请号：US16286637

申请日：2019-02-27

Applicant: CooperVision International Limited ,  The University of Melbourne

Inventor： Laura Elizabeth Downie ,  David Charles Jackson ,  Algis Jonas Vingrys ,  Nancy J. Keir ,  Inna Maltseva

IPC: G02C7/04 ,  G02C7/02 ,  G01N33/68 ,  C07K16/24

Abstract: Methods and devices to identify contact lens wearers predisposed to contact lens discomfort are described. The methods and devices involve obtaining a tear film sample from a person and determining an amount of interleukin-17A present in the tear film sample.