公开(公告)号：US20240321391A1

公开(公告)日：2024-09-26

申请号：US18734587

申请日：2024-06-05

申请人： Cyclica Inc.

发明人： Stephen Scott MACKINNON ,  Leonard David MORAYNISS ,  Jason MITAKIDIS ,  Fuad G GWADRY

IPC分类号： G16B20/30 ,  G16B5/00 ,  G16B15/00 ,  G16B15/30 ,  G16B20/00 ,  G16B35/00 ,  G16B35/20 ,  G16B50/00 ,  G16B50/10 ,  G16B50/30 ,  G16B99/00 ,  G16C20/60

CPC分类号： G16B20/30 ,  G16B5/00 ,  G16B15/00 ,  G16B15/30 ,  G16B20/00 ,  G16B35/00 ,  G16B35/20 ,  G16B50/00 ,  G16B50/10 ,  G16B50/30 ,  G16B99/00 ,  G16C20/60

摘要： The invention involves a method for identifying a target protein. The invention involves receiving a request to identify a target protein based on a ligand; identifying, using the ligand, a first protein, where the ligand binds with the first protein to fonn a ligand-protein complex; generating, a first binding site profile for the first protein, where the first binding site profile describes molecular properties of the first protein; obtaining, from a controlled server, structure data describing molecular properties of surfaces for a multitude of proteins, where the multitude of proteins comprises the target protein; identifying, using the first binding site profile and the structure data, the target protein; and presenting the target protein to a user.