公开(公告)号：US10081634B2

公开(公告)日：2018-09-25

申请号：US15312192

申请日：2015-06-23

申请人： Daewoong Pharmaceutical Co., Ltd.

发明人： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Yong Lee Bong

IPC分类号： C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/12 ,  C07D401/06 ,  C07D471/04

CPC分类号： C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/06 ,  C07D401/12 ,  C07D471/04

摘要： The present invention relates to a compound represented by chemical formula 1, which can be used for the prevention and treatment of diseases caused by abnormality in a prolyl-tRNA synthetase (PRS) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.

公开(公告)号：US20170088551A1

公开(公告)日：2017-03-30

申请号：US15312192

申请日：2015-06-23

申请人： DAEWOONG PHARMACEUTICAL CO., LTD.

发明人： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Yong Lee Bong

IPC分类号： C07D473/40 ,  C07D471/04 ,  C07D401/06

CPC分类号： C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/06 ,  C07D401/12 ,  C07D471/04

摘要： The present invention relates to a compound represented by chemical formula 1, which can be used for the prevention and treatment of diseases caused by abnormality in a prolyl-tRNA synthetase (PRS) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.