公开(公告)号：US20240245641A1

公开(公告)日：2024-07-25

申请号：US18562428

申请日：2022-05-20

Applicant: DAEWOONG PHARMACEUTICAL CO., LTD.

Inventor： Wan Huh ,  Hyun Woo Lim ,  Ji Soo Choi ,  Ju Mi Han ,  Joon Seok Park

IPC: A61K31/351 ,  A61K38/28 ,  A61P3/10

CPC classification number: A61K31/351 ,  A61K38/28 ,  A61P3/10

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diabetes mellitus in an animal of the family Canidae, including enavogliflozin as an active ingredient. The pharmaceutical composition, of the present invention, including enavogliflozin as an active ingredient exhibits an excellent blood glucose level control effect and thus can be effectively used for treating diabetes mellitus in an animal of the family Canidae.

公开(公告)号：US20200317673A1

公开(公告)日：2020-10-08

申请号：US16304798

申请日：2017-06-30

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： In Woo Kim ,  Mi Ryeong Han ,  Jakyung Yoo ,  Yun Ju Oh ,  Ji Duck Kim ,  Nam Youn Kim ,  Sun Ah Jun ,  Jun Hee Lee ,  Joon Seok Park

IPC: C07D487/04 ,  A61P29/00 ,  A61P35/00 ,  A61P37/00

Abstract: The present invention relates to a pyrazolopyrimidine derivative, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions.

公开(公告)号：US20160304460A1

公开(公告)日：2016-10-20

申请号：US15029638

申请日：2014-10-21

Applicant: DAEWOONG PHARMACEUTICAL CO., LTD.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Chang Min Park ,  Yun Soo Na ,  Min Jae Cho ,  Ho Bin Lee ,  Mi Ryeong Han ,  Yeon Jung Park ,  Ji Duck Kim

IPC: C07D213/82 ,  C07D471/04 ,  C07D498/08 ,  C07D417/06 ,  C07D401/06 ,  C07D401/12 ,  C07D401/04

CPC classification number: C07D213/82 ,  C07D213/63 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D417/06 ,  C07D471/04 ,  C07D487/04 ,  C07D498/08

Abstract: The present invention relates to novel oxodihydropyridinecarbohydrazide derivatives with excellent antifungal activities, an antifungal composition containing the same, and its use for the prevention and treatment of fungal infectious diseases. The oxodihydropyridinecarbohydrazide derivatives of the present invention have excellent antifungal and fungicidal activities, and thus will be useful for the prevention and treatment of various fungal infections by Candida spp., Aspergillus spp., Cryptococcus neoformans and Trichophyton spp., etc. Additionally, the oxodihydropyridinecarbohydrazide derivatives of the present invention, unlike other fungicidal preparations, can be orally administered.

Abstract translation: 本发明涉及具有优异抗真菌活性的新型氧代二氢吡啶碳酰肼衍生物，含有它们的抗真菌组合物及其用于预防和治疗真菌感染性疾病的用途。 本发明的氧代二氢吡啶碳酰肼衍生物具有优异的抗真菌和杀真菌活性，因此可用于预防和治疗念珠菌属，曲霉属（Aspergillus spp。），新隐隐球菌（Cryptococcus neoformans）和毛癣菌属（Trichophyton spp。）等各种真菌感染。另外，氧代二氢吡啶碳酰肼 本发明的衍生物与其它杀真菌剂不同，可以口服给药。

公开(公告)号：US20240307365A1

公开(公告)日：2024-09-19

申请号：US18577071

申请日：2022-07-22

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Caroline Hee Lee ,  Da Jeong Bae ,  Min Jae Cho ,  Joon Seok Park

IPC: A61K31/454 ,  A61K31/496 ,  A61K39/00 ,  A61P11/00 ,  A61P17/00

CPC classification number: A61K31/454 ,  A61K31/496 ,  A61P11/00 ,  A61P17/00 ,  A61K2039/505

Abstract: The pharmaceutical composition according to the present invention can be usefully used for the prevention or treatment of systemic fibrosis.

公开(公告)号：US20240216363A1

公开(公告)日：2024-07-04

申请号：US18288296

申请日：2022-05-02

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Caroline Hee Lee ,  Min Jae Cho ,  Min Young Park ,  Ju Mi Han ,  Joon Seok Park

IPC: A61K31/496 ,  A61K31/4418 ,  A61K31/454 ,  A61P11/00

CPC classification number: A61K31/496 ,  A61K31/4418 ,  A61K31/454 ,  A61P11/00

Abstract: The pharmaceutical composition according to the present invention is used at specific therapeutic regimen and dosage, and can be usefully used for the prevention or treatment of fibrosis.

公开(公告)号：US20230094404A1

公开(公告)日：2023-03-30

申请号：US17799774

申请日：2021-02-26

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Wol Young Kim ,  Qing Ri Li ,  Deok Ki Eom ,  Hyae Jung Hyun ,  Joon Seok Park

IPC: C07D417/14

Abstract: The present disclosure relates to a method for preparing a heterocyclic amine derivative, and the preparation method according to the present disclosure has an advantage that a heterocyclic amine derivative having a reduced impurity content can be prepared in a high yield.

公开(公告)号：US20220389010A1

公开(公告)日：2022-12-08

申请号：US17772855

申请日：2020-11-25

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Ji Duck Kim ,  Sun Ah Jun ,  Nam Youn Kim ,  In Woo Kim ,  Hyae Jung Hyun ,  Joon Seok Park

IPC: C07D471/04 ,  C07D519/00

Abstract: The present invention relates to a compound represented by the following Chemical Formula 1, or a pharmaceutically acceptable salt thereof, and the compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions: in Chemical Formula 1, R1 to R3 are as defined in the present specification.

公开(公告)号：US20250051302A1

公开(公告)日：2025-02-13

申请号：US18719677

申请日：2022-12-16

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon-Hwan Lee ,  Min Jae Cho ,  Joon Seok Park

IPC: C07D401/06 ,  C12P17/12

Abstract: The present invention relates to a method for preparing (2R, 3S)-2-(benzo[d]imidazolylpropyl)piperidin-3-ol derivatives, and the preparation method according to the present invention has the advantage that the compound can be prepared in high yield even with a shortened process.

公开(公告)号：US10011586B2

公开(公告)日：2018-07-03

申请号：US15556352

申请日：2016-06-07

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Bong Yong Lee

IPC: C07D401/06 ,  C07D417/14 ,  C07D401/14 ,  C07D471/04

CPC classification number: C07D401/06 ,  A61P35/00 ,  C07D401/14 ,  C07D417/14 ,  C07D471/04

Abstract: The present invention relates to a heterocyclic compound having a novel structure that can be used in the prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, a method for preparing the same, and a pharmaceutical composition comprising the same.

公开(公告)号：US09617216B2

公开(公告)日：2017-04-11

申请号：US15029638

申请日：2014-10-21

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Chang Min Park ,  Yun Soo Na ,  Min Jae Cho ,  Ho Bin Lee ,  Mi Ryeong Han ,  Yeon Jung Park ,  Ji Duck Kim

IPC: C07D213/63 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  A61K31/4412 ,  A61P31/04 ,  C07D213/82 ,  C07D417/06 ,  C07D487/04 ,  C07D498/08 ,  C07D471/04

CPC classification number: C07D213/82 ,  C07D213/63 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D417/06 ,  C07D471/04 ,  C07D487/04 ,  C07D498/08

Abstract: The present invention relates to novel oxodihydropyridinecarbohydrazide derivatives with excellent antifungal activities, an antifungal composition containing the same, and its use for the prevention and treatment of fungal infectious diseases. The oxodihydropyridinecarbohydrazide derivatives of the present invention have excellent antifungal and fungicidal activities, and thus will be useful for the prevention and treatment of various fungal infections by Candida spp., Aspergillus spp., Cryptococcus neoformans and Trichophyton spp., etc. Additionally, the oxodihydropyridinecarbohydrazide derivatives of the present invention, unlike other fungicidal preparations, can be orally administered.