公开(公告)号：US20180044322A1

公开(公告)日：2018-02-15

申请号：US15556352

申请日：2016-06-07

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Bong Yong Lee

IPC: C07D401/06 ,  C07D417/14 ,  C07D401/14 ,  C07D471/04

CPC classification number: C07D401/06 ,  C07D401/14 ,  C07D417/14 ,  C07D471/04

Abstract: The present invention relates to a heterocyclic compound having a novel structure that can be used in the prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, a method for preparing the same, and a pharmaceutical composition comprising the same.

公开(公告)号：US20210130358A1

公开(公告)日：2021-05-06

申请号：US16478920

申请日：2018-03-19

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： In Woo Kim ,  Ja Kyung Yoo ,  Ji Duck Kim ,  Sun Ah Jun ,  Jun Hee Lee

IPC: C07D487/04 ,  C07D519/00

Abstract: The present invention relates to a compound represented by the Chemical Formula 1 defined in the present specification, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions.

公开(公告)号：US10011586B2

公开(公告)日：2018-07-03

申请号：US15556352

申请日：2016-06-07

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Bong Yong Lee

IPC: C07D401/06 ,  C07D417/14 ,  C07D401/14 ,  C07D471/04

CPC classification number: C07D401/06 ,  A61P35/00 ,  C07D401/14 ,  C07D417/14 ,  C07D471/04

Abstract: The present invention relates to a heterocyclic compound having a novel structure that can be used in the prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, a method for preparing the same, and a pharmaceutical composition comprising the same.

公开(公告)号：US11084823B2

公开(公告)日：2021-08-10

申请号：US16478920

申请日：2018-03-19

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： In Woo Kim ,  Ja Kyung Yoo ,  Ji Duck Kim ,  Sun Ah Jun ,  Jun Hee Lee

IPC: A61K31/519 ,  C07D487/04 ,  C07D519/00

Abstract: The present invention relates to a compound represented by the Chemical Formula 1 defined in the present specification, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions.

公开(公告)号：US10081634B2

公开(公告)日：2018-09-25

申请号：US15312192

申请日：2015-06-23

Applicant: Daewoong Pharmaceutical Co., Ltd.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Yong Lee Bong

IPC: C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/12 ,  C07D401/06 ,  C07D471/04

CPC classification number: C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/06 ,  C07D401/12 ,  C07D471/04

Abstract: The present invention relates to a compound represented by chemical formula 1, which can be used for the prevention and treatment of diseases caused by abnormality in a prolyl-tRNA synthetase (PRS) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.

公开(公告)号：US20170088551A1

公开(公告)日：2017-03-30

申请号：US15312192

申请日：2015-06-23

Applicant: DAEWOONG PHARMACEUTICAL CO., LTD.

Inventor： Joon Seok Park ,  Youn Jung Yoon ,  Min Jae Cho ,  Ho Bin Lee ,  Ja Kyung Yoo ,  Yong Lee Bong

IPC: C07D473/40 ,  C07D471/04 ,  C07D401/06

CPC classification number: C07D473/40 ,  A61K31/4427 ,  C07D235/04 ,  C07D401/06 ,  C07D401/12 ,  C07D471/04

Abstract: The present invention relates to a compound represented by chemical formula 1, which can be used for the prevention and treatment of diseases caused by abnormality in a prolyl-tRNA synthetase (PRS) activity, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.