公开(公告)号：US20240167066A1

公开(公告)日：2024-05-23

申请号：US18283610

申请日：2022-03-24

申请人： DAICEL CORPORATION

发明人： Akira OTANI ,  Hiroaki YAMAMOTO ,  Kazuya MITSUHASHI ,  Takafumi MITACHI ,  Satoru FUKIYA ,  Atsushi YOKOTA

IPC分类号： C12P17/06 ,  C12N1/20 ,  C12N9/06 ,  C12N9/10 ,  C12P7/22 ,  C12P17/12 ,  C12R1/185 ,  C12R1/22 ,  C12R1/225 ,  C12R1/46

CPC分类号： C12P17/06 ,  C12N1/205 ,  C12N9/003 ,  C12N9/1014 ,  C12P7/22 ,  C12P17/12 ,  C12R2001/185 ,  C12R2001/22 ,  C12R2001/225 ,  C12R2001/46 ,  C12Y201/02001

摘要： An object of the present disclosure is at least to provide a technique for promoting elimination of a methyl group(s) of a methoxy group(s) in causing a microorganism having a demethylation ability of eliminating a methyl group(s) of a methoxy group(s) from a compound with the methoxy group(s) in a side chain(s) to produce a demethylated compound in which a methyl group(s) of a methoxy group(s) has eliminated from a compound with the methoxy group(s) in a side chain(s). The issue is solved by a method for producing a demethylated compound, comprising co-culturing, in a solution containing a compound with a methoxy group(s) in a side chain(s), a microorganism having a demethylation ability of eliminating a methyl group(s) of a methoxy group(s) from a compound with the methoxy group(s) in a side chain(s), and a microorganism having an activity to promote the demethylation, to produce the demethylated compound in which a methyl group(s) of a methoxy group(s) has eliminated from the compound with the methoxy group(s) in the side chain(s).