公开(公告)号：US11912787B2

公开(公告)日：2024-02-27

申请号：US17422494

申请日：2020-01-22

申请人： DERMAFIRM, INC.

发明人： Hoon Cha ,  Young Il Kwon ,  Sang Cheol Han ,  Jin Wook Kim ,  Mi Young Lee ,  Ga Hee Hur

IPC分类号： C07K7/06 ,  C07K19/00 ,  A61K38/06 ,  A61K38/08 ,  A61K8/64 ,  A61Q19/08 ,  A61P17/00 ,  C07K5/083 ,  C07K5/103 ,  A61K38/00

CPC分类号： C07K5/0806 ,  A61K8/64 ,  A61Q19/08 ,  C07K5/1008 ,  C07K19/00 ,  A61K38/00

摘要： Proposed is a peptide for skin anti-aging and anti-wrinkle, comprising a glycine-histidine-lysine tripeptide and polyarginine linked to the carboxy-terminus of the tripeptide, and a composition for skin anti-aging and anti-wrinkle comprising the peptide. The peptide and composition may enter the cytoplasm more rapidly and efficiently than a conventional GHK tripeptide, and may exhibit skin anti-aging and anti-wrinkle effects similar to those of the GHK tripeptide even at a lower concentration than that of the GHK tripeptide.