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公开(公告)号：US20240297028A1
公开(公告)日：2024-09-05
申请号：US18589559
申请日：2024-02-28
发明人： Scott DANIELS , Aaron STELLA , Michal WEINSTOCK
IPC分类号： H01J49/00 , G06F3/0484
CPC分类号： H01J49/0009 , G06F3/0484
摘要： A method for calibrating a mass spectrometry (MS) system includes: receiving at least one input through a corresponding to a calibrator in a sample, wherein the sample includes an analyte, and wherein the sample is analyzed by the MS system; automatically determining a plurality of transitions in the sample corresponding to the calibrator according to natural abundances of isotopes; automatically determining concentrations of the plurality of transitions according to a concentration of the calibrator in the sample; identifying a plurality of transitions as calibrator transitions and for identifying a different one of the plurality of transitions as an internal standard; detecting a concentration of each of the plurality of transitions and the calibrator in the sample; automatically calibrating the MS system based in part on the detected concentrations of the plurality of calibrator transitions and the internal standard; and detecting the concentration of the analyte in response to execution of the calibration instructions.
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公开(公告)号：US20240230633A1
公开(公告)日：2024-07-11
申请号：US18562090
申请日：2022-05-18
IPC分类号： G01N33/543 , G01N33/94
CPC分类号： G01N33/54326 , G01N33/54353 , G01N33/94
摘要： Methods and kits for preparing liquid samples are presently claimed and described. The method may include treating a liquid sample with enzyme-conjugated magnetic beads are suspended in a buffer solution that comprises at least one internal standard, hydrolyzing the liquid sample to prepare a hydrolysate, and purifying the hydrolysate with magnetic based purification. Kits for preparing a liquid sample can include the, a liquid chromatography column, one or more solvents to be used as mobile phases, one or more calibrant solutions, and instructions for use.
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公开(公告)号：US20230333130A1
公开(公告)日：2023-10-19
申请号：US18016210
申请日：2021-07-14
发明人： Aaron STELLA
CPC分类号： G01N35/0099 , G01N35/10 , H01J49/0413 , B01L3/5082 , B01L2200/18 , B01L2300/0858 , B01L2200/025
摘要： An analyzer and sample handling system suitable for retrieving and processing a sample housed within a suitably configured reaction vessel, and then discarding the used reaction vessel by vertically or axially pushing downward on the vessel supported in a suitably configured tray with a pressing member that forms part of an autosampler assembly are disclosed herein.
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