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    Reliable request-response messaging over a request-response transport
    7.
    发明申请
    Reliable request-response messaging over a request-response transport 有权
    通过请求 - 响应传输提供可靠的请求 - 响应消息

    公开(公告)号：US20060206558A1

    公开(公告)日：2006-09-14

    申请号：US11075418

    申请日：2005-03-08

    申请人： Shy Cohen ,  Kirill Gavrylyuk ,  Ondrej Hrebicek ,  Richard Hill ,  Stefan Batres

    发明人： Shy Cohen ,  Kirill Gavrylyuk ,  Ondrej Hrebicek ,  Richard Hill ,  Stefan Batres

    IPC分类号： G06F15/16

    CPC分类号： H04L29/06 ,  H04L67/42 ,  H04L69/32 ,  H04L69/329 ,  H04L69/40 ,  Y10S707/99945 ,  Y10S707/99948

    摘要： A reliable request-response mechanism allows a requesting computer system and a responding computer system in an established end-to-end connection to send and receive messages in a manner that the responding computer system processes a request as intended by the requesting computer system, such that all the message communication is initiated by the requesting computer system. The requesting computer system and responding computer system can accommodate a wide range of messaging failures, such as intermittent network connections or failure of a transport of SOAP intermediary by resending cached versions of previously sent messages, and by acknowledging receipt of each message received. Cached messages on either computer system are deleted after being appropriately acknowledged. After all sent messages have been acknowledged by the responding computer, and the requesting computer has received all of the response messages from the responding computer, the end-to-end connection is terminated with an exchange of connection termination messages.

    摘要翻译： 可靠的请求 - 响应机制允许请求计算机系统和建立的端对端连接中的响应计算机系统以响应的计算机系统按请求计算机系统的预期处理请求的方式来发送和接收消息， 所有消息通信由请求计算机系统发起。 请求计算机系统和响应的计算机系统可以适应各种消息传递失败，例如间歇性网络连接或通过重新发送先前发送的消息的缓存版本的SOAP中介的传输失败，以及通过确认收到的每个消息的接收。 任何计算机系统上的缓存消息在被适当确认后被删除。 在所有发送的消息已经被响应的计算机确认，并且请求计算机已经从响应的计算机接收到所有的响应消息之后，端到端连接通过交换连接终止消息来终止。

    Heat spreading thermal interface structure
    8.
    发明申请
    Heat spreading thermal interface structure 有权
    热扩散热界面结构

    公开(公告)号：US20050045372A1

    公开(公告)日：2005-03-03

    申请号：US10886841

    申请日：2004-07-07

    申请人： Richard Hill ,  Jason Strader ,  James Latham

    发明人： Richard Hill ,  Jason Strader ,  James Latham

    IPC分类号： H01L23/427 ,  H05K1/16

    CPC分类号： H01L23/4275 ,  H01L2924/0002 ,  Y10T428/12396 ,  Y10T428/12486 ,  Y10T428/12528 ,  Y10T428/12556 ,  H01L2924/00

    摘要： The thermal interface structure of the present invention is suited for use in a non-referenced die system between a heat source and heat sink spaced up to 300 mils apart and comprises a plurality of layers including a core body of high conductivity metal or metal alloy having opposite sides, a soft thermal interface layer disposed on one side of the core body for mounting against the heat sink and a thin layer of a phase change material disposed on the opposite side of the core body for mounting against the heat source wherein the surface area dimension (footprint) of the core body is substantially larger than the surface area of the heat source upon which the phase change material is mounted to minimize the thermal resistance between the heat source and the heat sink and wherein said soft thermal interface layer is of a thickness sufficient to accommodate a variable spacing between the heat source and the heat sink of up to 300 mils.

    摘要翻译： 本发明的热界面结构适用于间隔高达300密耳间隔的热源和散热器之间的非参考模具系统，并且包括多个层，包括具有高导电性金属或金属合金的芯体，其具有 相对侧，设置在芯体的一侧上用于安装在散热器上的软热界面层和设置在芯体的相对侧上的相变材料的薄层，用于安装在热源上，其中表面积 芯体的尺寸（占地面积）基本上大于安装有相变材料的热源的表面积，以最小化热源和散热器之间的热阻，并且其中所述软热界面层为 厚度足以容纳高达300密耳的热源和散热器之间的可变间隔。

    Verotoxin pharmaceutical compositions and medical treatments therewith
    9.
    发明授权
    Verotoxin pharmaceutical compositions and medical treatments therewith 失效
    Verotoxin药物组合物及其治疗

    公开(公告)号：US06835710B1

    公开(公告)日：2004-12-28

    申请号：US09632056

    申请日：2000-08-03

    申请人： Clifford A. Lingwood ,  Hannah Farkas-Himsley ,  Richard Hill

    发明人： Clifford A. Lingwood ,  Hannah Farkas-Himsley ,  Richard Hill

    IPC分类号： C07K1400

    CPC分类号： A61K51/08 ,  A61K38/164 ,  C07K14/245

    摘要： Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.

    摘要翻译： 已经发现包含已知的毒素，特别是藜芦毒素1的药物组合物可用于治疗哺乳动物瘤形成，特别是卵巢癌和皮肤癌。 令人惊奇的是，虽然verotoxin 1以前已被证明在体外具有抗肿瘤活性，但是非致死剂量的verotoxin1已被证明在体内具有治疗性的抗肿瘤活性。