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公开(公告)号:US09745387B2
公开(公告)日:2017-08-29
申请号:US14420985
申请日:2013-08-15
Applicant: Dow Global Technologies LLC
Inventor: Meinolf Brackhagen , Nicholas S. Grasman , Yongfu Li , David M. Meunier , Oliver Petermann , Matthias Sprehe
CPC classification number: C08B13/00 , A61K9/10 , A61K9/146 , A61K9/2866 , C08B11/20
Abstract: A partially cross-linked esterified cellulose ether having A) groups of the formula —C(O)—R—COOA or a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>100 k)−Wf(>100 k)XL]/Wf(>100 k)XL is at least 0.20, wherein Wf(>100 k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>100 k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms.
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公开(公告)号:US20150203597A1
公开(公告)日:2015-07-23
申请号:US14420985
申请日:2013-08-15
Applicant: Dow Global Technologies LLC
Inventor: Meinolf Brackhagen , Nicholas S. Grasman , Yongfu Li , David M. Meunier , Oliver Petermann , Matthias Sprehe
CPC classification number: C08B13/00 , A61K9/10 , A61K9/146 , A61K9/2866 , C08B11/20
Abstract: A partially cross-linked esterified cellulose ether having A) groups of the formula —C(O)—R—COOA or a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>100 k)−Wf(>100 k)XL]/Wf(>100 k)XL is at least 0.20, wherein Wf(>100 k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>100 k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms.
Abstract translation: 具有A)基团的式-C(O)-R-COOA或脂族一价酰基和式-C(O)-R-COOA基团的部分交联的酯化纤维素醚,其中R为 二价脂族或芳族烃基,A是氢或阳离子,B)分子量分布使得[Wf(> 100k)-Wf(> 100k)XL] / Wf(> 100k)XL为 至少0.20,其中Wf(> 100k)是超过100,000g / mol的酯化纤维素醚的总重量分数,Wf(> 100k)XL是甲基化酯化的超过100,000g / mol的重量分数 纤维素醚可用作药物剂型的肠溶性聚合物。
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公开(公告)号:US11931447B2
公开(公告)日:2024-03-19
申请号:US17434440
申请日:2020-04-16
Applicant: Dow Global Technologies LLC , Rohm and Haas Company
Inventor: Luqing Qi , Liang Chen , Lu Bai , Lyndsay M. Leal , David M. Meunier , Yunshen Chen , Fanwen Zeng
CPC classification number: A61K8/8152 , A61K8/25 , A61K8/92 , A61Q5/02 , A61Q19/10 , A61K2800/48
Abstract: A polymer/hydrophilic silica blend is provided comprising (a) a thickening polymer powder, comprising (i) structural units of C4-8 alkyl (meth)acrylate monomer; (ii) structural units of (meth)acrylic acid monomer, and (iii) structural units of a specialized associative monomer of formula (I)
wherein R1 is a linear saturated C10-20 alkyl group; and n is an average of 20 to 28; and (b) a hydrophilic silica powder; wherein the weight ratio of hydrophilic silica powder to thickening polymer powder in the polymer/hydrophilic silica blend is 1:9 to 9:1. Also provided are personal care compositions containing same and methods of using same.-
公开(公告)号:US20200015493A1
公开(公告)日:2020-01-16
申请号:US16335959
申请日:2017-09-14
Applicant: DOW GLOBAL TECHNOLOGIES LLC
Inventor: Roja Ergun , David M. Meunier
IPC: A23D9/007
Abstract: Provided is a composition comprising one or more ethylcellulose polymer, one or more oil, and stearic acid.
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公开(公告)号:US12201710B2
公开(公告)日:2025-01-21
申请号:US17601111
申请日:2020-04-16
Applicant: Dow Global Technologies LLC , Rohm and Haas Company
Inventor: Luqing Qi , Liang Chen , Lu Bai , Lyndsay M. Leal , David M. Meunier , Yunshen Chen , Fanwen Zeng
Abstract: A hydrophilic silica/polymer blend is provided comprising (a) a hydrophilic silica powder; and (b) a thickening polymer powder, comprising (i) structural units of C4-8 alkyl (meth)acrylate monomer; (ii) structural units of (meth)acrylic acid monomer; (iii) structural units of (methoxy) poly(ethylene glycol) (meth)acrylate monomer; and (iv) structural units of multiethylenically unsaturated monomer; wherein the weight ratio of hydrophilic silica powder to thickening polymer powder in the hydrophilic silica/polymer blend is 1:9 to 9:1. Also provided are personal care compositions containing same and methods of using same.
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公开(公告)号:US20220160596A1
公开(公告)日:2022-05-26
申请号:US17601111
申请日:2020-04-16
Applicant: Dow Global Technologies LLC , Rohm and Haas Company
Inventor: Luqing Qi , Liang Chen , Lu Bai , Lyndsay M. Leal , David M. Meunier , Yunshen Chen , Fanwen Zeng
Abstract: A hydrophilic silica/polymer blend is provided comprising (a) a hydrophilic silica powder; and (b) a thickening polymer powder, comprising (i) structural units of C4-8 alkyl (meth)acrylate monomer; (ii) structural units of (meth)acrylic acid monomer; (iii) structural units of (methoxy) poly(ethylene glycol) (meth)acrylate monomer; and (iv) structural units of multiethylenically unsaturated monomer; wherein the weight ratio of hydrophilic silica powder to thickening polymer powder in the hydrophilic silica/polymer blend is 1:9 to 9:1. Also provided are personal care compositions containing same and methods of using same.
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公开(公告)号:US20220151908A1
公开(公告)日:2022-05-19
申请号:US17440402
申请日:2020-04-16
Applicant: Dow Global Technologies LLC , Rohm and Haas Company
Inventor: Luqing Qi , Liang Chen , Lu Bai , Lyndsay M. Leal , David M. Meunier , Yunshen Chen , Fanwen Zeng
Abstract: A polymer oil blend is provided comprising (a) a cosmetically acceptable long chain hydrophobic ester oil, wherein the cosmetically acceptable long chain hydrophobic ester oil comprises aliphatic C>12-24 alkyl triglycerides; (b) a thickening polymer powder, wherein the thickening polymer powder comprises: (i) 96 to 99.9 wt %, based on weight of the thickening polymer powder, of structural units of C4-8 alkyl (meth)acrylate monomer; (ii) 0.1 to 2 wt %, based on weight of the thickening polymer powder, of structural units of (meth)acrylic acid monomer; (iii) 0 to 2 wt %, based on weight of the thickening polymer powder, of structural units of multi-ethylenically unsaturated crosslinking monomer; and (c) a silica powder; and wherein the weight ratio of silica powder/thickening polymer powder is ≥0.25. Also provided are personal care compositions containing same and methods of using same.
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公开(公告)号:US20220142903A1
公开(公告)日:2022-05-12
申请号:US17434440
申请日:2020-04-16
Applicant: Dow Global Technologies LLC , Rohm and Haas Company
Inventor: Luqing Qi , Liang Chen , Lu Bai , Lyndsay M. Leal , David M. Meunier , Yunshen Chen , Fanwen Zeng
Abstract: A polymer/hydrophilic silica blend is provided comprising (a) a thickening polymer powder, comprising (i) structural units of C4-8 alkyl (meth)acrylate monomer; (ii) structural units of (meth)acrylic acid monomer, and (iii) structural units of a specialized associative monomer of formula (I) wherein R1 is a linear saturated C10-20 alkyl group; and n is an average of 20 to 28; and (b) a hydrophilic silica powder; wherein the weight ratio of hydrophilic silica powder to thickening polymer powder in the polymer/hydrophilic silica blend is 1:9 to 9:1. Also provided are personal care compositions containing same and methods of using same.
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