公开(公告)号：US11364208B2

公开(公告)日：2022-06-21

申请号：US16628434

申请日：2018-06-28

Applicant: DSM IP ASSETS B.V.

Inventor： Christine Mendrok-Edinger ,  Sebastien Mongiat ,  Thomas Rudolph

IPC: A61K31/12 ,  A61P17/10 ,  A61P31/10 ,  A61K8/04 ,  A61K8/06 ,  A61K8/35 ,  A61K9/107 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q17/00 ,  A61Q19/00

Abstract: The present invention relates to topical compositions comprising erythrulose and hydroxyacetophenone as well as the use thereof for the prevention and/or treatment of ailments associated with Malassezia yeast, Propionibacterium acnes as well as the protection against molds such as in particular Aspergillus brasiliensis.

公开(公告)号：US11324680B2

公开(公告)日：2022-05-10

申请号：US16628426

申请日：2018-06-28

Applicant: DSM IP ASSETS B.V.

Inventor： Christine Mendrok-Edinger ,  Sebastien Mongiat ,  Thomas Rudolph

IPC: A61K8/35 ,  A61K8/37 ,  A61K8/60 ,  A61K9/107 ,  A61Q17/00 ,  A61Q19/00

Abstract: The present invention relates to topical compositions comprising erythrulose and a caprylate, characterized in that the amount of the caprylate in the composition is 5 higher than the amount of erythrulose.

公开(公告)号：US10702458B2

公开(公告)日：2020-07-07

申请号：US16312593

申请日：2017-06-27

Applicant: DSM IP ASSETS B.V.

Inventor： Cyrille Deshayes ,  Andre Duesterloh ,  Anne Janssen ,  Thomas Rudolph

IPC: A61K8/06 ,  A61K8/25 ,  A61K8/29 ,  A61K8/34 ,  A61K8/55 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q17/04 ,  A61Q19/04

Abstract: The present invention relates to topical compositions comprising at least one inorganic micropigment and a cetyl phosphate surfactant mixture consisting essentially of mono- and/or dicetyl esters of phosphoric acid or salts thereof and cetylalcohol and inorganic phosphate and heavy metals and water, characterized in that the surfactant mixture contains no organochlorine impurities and has an inorganic phosphate content of less than 0.7 wt.-% and a heavy metal content of less than 12 ppm.

公开(公告)号：US11191772B2

公开(公告)日：2021-12-07

申请号：US16628797

申请日：2018-06-28

Applicant: DSM IP ASSETS B.V.

Inventor： Christine Mendrok-Edinger ,  Sebastien Mongiat ,  Thomas Rudolph

IPC: A61K31/7004 ,  A61K8/06 ,  A61K8/60 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/10

Abstract: The present invention relates to the use of erythrulose as antimicrobial agent as well as to composition comprising said agent.

公开(公告)号：US11224563B2

公开(公告)日：2022-01-18

申请号：US16312575

申请日：2017-06-27

Applicant: DSM IP ASSETS B.V.

Inventor： Andre Duesterloh ,  Anne Janssen ,  Christeine Mendrok-Edinger ,  Karina Radomsky ,  Thomas Rudolph

IPC: A61K8/55 ,  A61K8/06 ,  A61K8/34 ,  A61Q17/04 ,  A61Q19/00

Abstract: The present invention relates to topical composition comprising a cetyl phosphate surfactant mixture consisting essentially of mono- and/or dicetyl esters of phosphoric acid or salts thereof and cetylalcohol and inorganic phosphate and heavy metals and water, characterized in that the surfactant mixture contains no organochlorine impurities and has an inorganic phosphate content of less than 0.7 wt.-% and a heavy metal content of less than 12 ppm.