公开(公告)号：US20130137944A1

公开(公告)日：2013-05-30

申请号：US13816035

申请日：2011-08-11

申请人： Dae Hong Jeong ,  Keon Wook Kang ,  Dong Soo Lee ,  Yoon Sik Lee ,  Gun Sung Kim ,  Bong Hyun Jun ,  Jin Chul Paeng ,  Ho Young Lee ,  Yun Sang Lee

发明人： Dae Hong Jeong ,  Keon Wook Kang ,  Dong Soo Lee ,  Yoon Sik Lee ,  Gun Sung Kim ,  Bong Hyun Jun ,  Jin Chul Paeng ,  Ho Young Lee ,  Yun Sang Lee

IPC分类号： A61B5/00

CPC分类号： A61B5/0071 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/00186 ,  A61B1/015 ,  A61B1/043 ,  A61B1/063 ,  A61B1/126 ,  A61B5/0062 ,  A61B5/0068 ,  A61B5/0075 ,  A61B5/0084 ,  A61K49/0065 ,  B82Y30/00

摘要： Method pertains to a medical imaging device for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets. The method includes: injecting at least one marker particle including Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, into which fluorescent components are introduced, into the body of the animal using a spray or the like, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.

摘要翻译： 方法涉及用于同时检测多个荧光和拉曼信号靶的荧光和拉曼信号的医学成像装置。 该方法包括：将至少一种包括拉曼标记物和受体的标记物质注射到可以是人的动物体内; 将激光束照射到动物的身体上; 并且在激光束照射之后分别检测由标记物粒子发射的光信号作为荧光信号和拉曼信号。 即使不使用不同的光纤单独地扫描由标记颗粒发射的光信号，也可以执行多个目标的同时检测。 作为检查可以通过使用喷雾等将引入了荧光成分的表面增强拉曼标记颗粒注入动物的体内，可以增强弱拉曼信号，以获得更准确的诊断结果 实时。