公开(公告)号：US06345617B1

公开(公告)日：2002-02-12

申请号：US08938686

申请日：1997-09-26

申请人： Dan Engelbreth ,  Robert Morton ,  Martin Foley ,  Mark Nagel ,  Jolyon P. Mitchell

发明人： Dan Engelbreth ,  Robert Morton ,  Martin Foley ,  Mark Nagel ,  Jolyon P. Mitchell

IPC分类号： A61M1100

CPC分类号： A61M15/0086 ,  A61M11/002 ,  A61M11/003 ,  A61M15/009

摘要： An improved aerosol medication delivery apparatus and system. The aerosol medication delivery apparatus includes a canister-holding portion and a chamber housing. The canister-holding portion has a receptacle for receipt of a pMDI canister containing a medication and a propellant to provide the aerosol medication delivery system. The canister-holding portion has a discharge orifice communicating with the receptacle to direct an aerosol into an interior of the chamber housing at an input end thereof. The chamber housing also has an output end from which medication can be withdrawn by inhalation by a patient. According to one aspect, the aerosol delivery system includes a containment baffle located at the output end of the chamber housing to partially block the output. According to another aspect, the canister-holding portion and the chamber housing are coupled together by a mechanism that provides for the canister-holding portion to be retracted into the chamber housing for storage. The coupling mechanism also allows the canister-holding portion to be extracted from its storage position in the chamber housing and pivoted into position for use when dispensing medication. In another aspect, an aerosol medication apparatus includes a chamber housing with an input end to receive the discharge of a medication from a pMDI canister and an output end including a containment baffle that partially blocks the output end. The pMDI canister may be received in an elastomeric backpiece that is adapted to accommodate various sizes of actuator boot mouthpieces.

摘要翻译： 改进的气溶胶药物输送装置和系统。 气溶胶药物输送装置包括罐保持部分和腔室壳体。 罐保持部分具有用于接收含有药物和推进剂的pMDI罐的容器，以提供气溶胶药物输送系统。 罐保持部分具有与容器连通的排出孔，以将烟雾引导到其壳体的输入端的内部。 腔室还具有输出端，药物可由该输出端吸入患者体内。 根据一个方面，气溶胶输送系统包括位于腔室壳体的输出端处以部分地阻挡输出的容纳挡板。 根据另一方面，罐保持部分和腔室壳体通过机构联接在一起，该机构提供将容器保持部分缩回到腔室中用于储存。 联接机构还允许罐保持部分从其在容器壳体中的存储位置提取并且枢转到用于分配药物时使用的位置。 在另一方面，一种气溶胶药物装置包括具有输入端的腔室壳体，用于接收来自pMDI罐的药物的排出以及包括部分阻塞输出端的容纳挡板的输出端。 pMDI罐可以被接收在适于容纳各种尺寸的致动器引导嘴的弹性体背部件中。

公开(公告)号：US08196483B2

公开(公告)日：2012-06-12

申请号：US12326450

申请日：2008-12-02

申请人： Myles Limbrick ,  Robert Morton ,  Mark Nagel ,  Jolyon Mitchell ,  Peter Gubbels ,  Kimberly Wiersema ,  Cathy Doyle ,  Valentina Avvakoumova

发明人： Myles Limbrick ,  Robert Morton ,  Mark Nagel ,  Jolyon Mitchell ,  Peter Gubbels ,  Kimberly Wiersema ,  Cathy Doyle ,  Valentina Avvakoumova

IPC分类号： G01D21/02

CPC分类号： A61M16/06 ,  A61M15/009 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2209/02 ,  A61M2209/084 ,  A61M2210/0606 ,  A62B27/00 ,  G09B23/32

摘要： Systems and methods for evaluating medication delivery from valved holding chambers (VHCs) with a facemask using a model face of a child or a model face of an infant are disclosed. Generally, the model face includes a base, an elastomer cast, an air pocket, and a mouth opening. The elastomer cast is positioned on at least a portion of a top of the base. The elastomer simulates soft tissues in a face and defines at least a nose, a chin, and a mouth sized to simulate a nose, a chin, and a mouth of a child. The air pocket is positioned between the base and the elastomer case below at least the nose, the chin, and the mouth of the elastomer cast. The mouth opening defines a passageway through the base, the air pocket, and the mouth of the elastomer cast.

摘要翻译： 公开了使用儿童的模型面或婴儿的模型面评估带有面罩的带阀门的室内（VHC）的药物递送的系统和方法。 通常，模型面包括基座，弹性体铸件，气穴和开口。 弹性体铸件位于基座顶部的至少一部分上。 弹性体模拟面部中的软组织，并至少定义了一个鼻子，下巴和一个大小适合模拟孩子鼻子，下巴和嘴巴的嘴巴。 气囊位于底座和弹性体外壳之间，至少在弹性体铸件的鼻子，下巴和嘴部下方。 开口限定通过基座，气穴和弹性体浇口的口的通道。

公开(公告)号：US20090173173A1

公开(公告)日：2009-07-09

申请号：US12326450

申请日：2008-12-02

申请人： Myles Limbrick ,  Robert Morton ,  Mark Nagel ,  Jolyon Mitchell ,  Peter Gubbels ,  Kimberly Wiersema ,  Cathy Doyle ,  Valentina Avvakoumova

发明人： Myles Limbrick ,  Robert Morton ,  Mark Nagel ,  Jolyon Mitchell ,  Peter Gubbels ,  Kimberly Wiersema ,  Cathy Doyle ,  Valentina Avvakoumova

IPC分类号： G01M19/00

CPC分类号： A61M16/06 ,  A61M15/009 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2209/02 ,  A61M2209/084 ,  A61M2210/0606 ,  A62B27/00 ,  G09B23/32

摘要： Systems and methods for evaluating medication delivery from valved holding chambers (VHCs) with a facemask using a model face of a child or a model face of an infant are disclosed. Generally, the model face includes a base, an elastomer cast, an air pocket, and a mouth opening. The elastomer cast is positioned on at least a portion of a top of the base. The elastomer simulates soft tissues in a face and defiens at least a nose, a chin, and a mouth sized to simulate a nose, a chin, and a mouth of a child. The air pocket is positioned between the base and the elastomer case below at least the nose, the chin, and the mouth of the elastomer cast. The mouth opening defines a passageway through the base, the air pocket, and the mouth of the elastomer cast.

摘要翻译： 公开了使用儿童的模型面或婴儿的模型面评估带有面罩的带阀门的室内（VHC）的药物递送的系统和方法。 通常，模型面包括基座，弹性体铸件，气穴和开口。 弹性体铸件位于基座顶部的至少一部分上。 弹性体模拟面部的软组织，并至少起鼻针，下巴和口径，以模拟儿童的鼻子，下巴和嘴巴。 气囊位于底座和弹性体外壳之间，至少在弹性体铸件的鼻子，下巴和嘴部下方。 开口限定通过基座，气穴和弹性体浇口的口的通道。

公开(公告)号：US20120048264A1

公开(公告)日：2012-03-01

申请号：US13216759

申请日：2011-08-24

申请人： Bryan Finlay ,  Michael Nuttall ,  Brandon Coultes ,  Mark Nagel ,  Mark Pickard

发明人： Bryan Finlay ,  Michael Nuttall ,  Brandon Coultes ,  Mark Nagel ,  Mark Pickard

IPC分类号： A61M11/00

CPC分类号： A61M11/02 ,  A61M11/06 ,  A61M13/003 ,  A61M15/009 ,  A61M16/0463 ,  A61M16/0477 ,  A61M16/0486 ,  A61M16/0816 ,  A61M16/1095 ,  A61M16/16 ,  A61M16/161 ,  A61M39/08 ,  A61M39/105 ,  A61M2039/082 ,  A61M2202/0225 ,  A61M2202/0488 ,  A61M2205/75

摘要： An aerosol delivery system is disclosed that is a single-use (disposable) continuous nebulizer system designed for use with mechanically ventilated patients to aerosolize medications for inhalation with a general purpose nebulizer, or for connection with devices usable in endoscopic procedures. The system separates the liquid reservoir from the nebulization process taking place either at the adapter hub, where it fits into an endotracheal tube (ETT), or a gas humidifier, where the aerosol may treat a gas used in an endoscopic procedure, with a multi-lumen tube configured to nebulize liquid and air at its distal end. The refillable liquid reservoir is mounted away from the immediate treatment zone, avoiding orientation issues associated with other types of nebulizers having a self-contained reservoir. The system can produce aerosols having a wide range of droplet sizes, depending upon central lumen diameter, with values of MMAD that range from 4 to 30 μm.

摘要翻译： 公开了一种气溶胶输送系统，其是单次使用（一次性）连续雾化器系统，其被设计用于机械通气患者，以使用通用雾化器吸入药物雾化，或用于与可用于内窥镜手术的装置连接。 该系统将液体储存器与雾化过程进行分离，该装置发生在适配器毂处，其适配于气管插管（ETT）或气体加湿器中，其中气溶胶可以处理内窥镜程序中使用的气体， 配置为在其远端处喷射液体和空气的管腔。 可再填充液体储存器远离立即处理区域，避免与具有独立储存器的其它类型的喷雾器相关的取向问题。 该系统可以根据中心管腔直径产生范围广泛的液滴尺寸的气溶胶，其中MMAD的值范围为4至30μm。

公开(公告)号：US09032951B2

公开(公告)日：2015-05-19

申请号：US13216759

申请日：2011-08-24

申请人： Bryan Finlay ,  Michael Nuttall ,  Brandon Coultes ,  Mark Nagel ,  Mark Pickard

发明人： Bryan Finlay ,  Michael Nuttall ,  Brandon Coultes ,  Mark Nagel ,  Mark Pickard

IPC分类号： A61M11/00 ,  A61M15/00 ,  A61M16/00 ,  A61M37/00 ,  A61M13/00 ,  A61M16/04 ,  A61M16/08 ,  A61M16/10 ,  A61M11/06 ,  A61M16/16

CPC分类号： A61M11/02 ,  A61M11/06 ,  A61M13/003 ,  A61M15/009 ,  A61M16/0463 ,  A61M16/0477 ,  A61M16/0486 ,  A61M16/0816 ,  A61M16/1095 ,  A61M16/16 ,  A61M16/161 ,  A61M39/08 ,  A61M39/105 ,  A61M2039/082 ,  A61M2202/0225 ,  A61M2202/0488 ,  A61M2205/75

摘要： An aerosol delivery system is disclosed that is a single-use (disposable) continuous nebulizer system designed for use with mechanically ventilated patients to aerosolize medications for inhalation with a general purpose nebulizer, or for connection with devices usable in endoscopic procedures. The system separates the liquid reservoir from the nebulization process taking place either at the adapter hub, where it fits into an endotracheal tube (ETT), or a gas humidifier, where the aerosol may treat a gas used in an endoscopic procedure, with a multi-lumen tube configured to nebulize liquid and air at its distal end. The refillable liquid reservoir is mounted away from the immediate treatment zone, avoiding orientation issues associated with other types of nebulizers having a self-contained reservoir. The system can produce aerosols having a wide range of droplet sizes, depending upon central lumen diameter, with values of MMAD that range from 4 to 30 μm.

摘要翻译： 公开了一种气溶胶输送系统，其是单次使用（一次性）连续雾化器系统，其被设计用于机械通气患者，以使用通用雾化器吸入药物雾化，或用于与可用于内窥镜手术的装置连接。 该系统将液体储存器与雾化过程进行分离，该装置发生在适配器毂处，其适配于气管插管（ETT）或气体加湿器中，其中气溶胶可以处理内窥镜程序中使用的气体， 配置为在其远端处喷射液体和空气的管腔。 可再填充液体储存器远离立即处理区域，避免与具有独立储存器的其它类型的喷雾器相关的取向问题。 该系统可以根据中心管腔直径产生范围广泛的液滴尺寸的气溶胶，其中MMAD的值范围为4至30μm。