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公开(公告)号:US20140308206A1
公开(公告)日:2014-10-16
申请号:US14122880
申请日:2012-06-01
CPC分类号: C07K16/283 , A61K39/3955 , A61K48/00 , A61K49/0002 , A61K2039/505 , C07K2317/565 , C07K2317/94 , G01N33/6854
摘要: The disclosure relates to antibodies that bind FcRn and methods of using these antibodies.
摘要翻译: 本公开涉及结合FcRn的抗体和使用这些抗体的方法。
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公开(公告)号:US08822653B2
公开(公告)日:2014-09-02
申请号:US12985914
申请日:2011-01-06
IPC分类号: A61K39/395 , C07K16/40
CPC分类号: C07K16/40 , A61K49/0004 , A61K2039/505 , C07K2317/76 , C07K2317/92
摘要: Plasma kallikrein binding proteins and methods of using such proteins are described.
摘要翻译: 描述了血浆激肽释放酶结合蛋白和使用这些蛋白质的方法。
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公开(公告)号:US20120027686A1
公开(公告)日:2012-02-02
申请号:US13192786
申请日:2011-07-28
IPC分类号: A61K39/395 , C12N15/13 , A61P11/00 , C12N1/19 , C40B40/10 , C12N15/62 , C12N15/81 , A61K49/16 , G01N33/573
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/564 , G01N2800/122
摘要: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
摘要翻译: 本发明的特征在于hK1结合多肽以及包含这种多肽的组合物以及制备和使用这些多肽的方法。
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公开(公告)号:US07993646B2
公开(公告)日:2011-08-09
申请号:US11956792
申请日:2007-12-14
IPC分类号: A61K39/395
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/564 , G01N2800/122
摘要: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
摘要翻译: 本发明的特征在于hK1结合多肽以及包含这种多肽的组合物以及制备和使用这些多肽的方法。
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5.KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY 有权
标题翻译: KDR和VEGF / KDR结合肽及其在诊断和治疗中的应用公开(公告)号:US20100003195A1
公开(公告)日:2010-01-07
申请号:US12480578
申请日:2009-06-08
申请人: Aaron K. Sato , Daniel J. Sexton , Daniel T. Dransfield , Robert C. Ladner , Christophe Arbogast , Philippe Bussat , Hong Fan , Sudha Khurana , Karen E. Linder , Edmund R. Marinelli , Palaniappa Nanjappan , Adrian D. Nunn , Radhakrishna Pillai , Sibylle Pochon , Kondareddiar Ramalingam , Ajay Shrivastava , Bo Song , Rolf E. Swenson , Mathew A. Von Wronski
发明人: Aaron K. Sato , Daniel J. Sexton , Daniel T. Dransfield , Robert C. Ladner , Christophe Arbogast , Philippe Bussat , Hong Fan , Sudha Khurana , Karen E. Linder , Edmund R. Marinelli , Palaniappa Nanjappan , Adrian D. Nunn , Radhakrishna Pillai , Sibylle Pochon , Kondareddiar Ramalingam , Ajay Shrivastava , Bo Song , Rolf E. Swenson , Mathew A. Von Wronski
IPC分类号: A61K49/22
CPC分类号: A61K49/221 , A61K38/00 , A61K47/62 , A61K49/223 , A61K51/088 , C07K7/08 , C07K14/001 , C07K14/52 , C07K14/71 , C07K2319/00 , Y02A50/411 , Y02A50/58
摘要: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD
摘要翻译: 本发明提供了包含用于KDR或VEGF / KDR复合物的至少一个结合部分的多肽,肽二聚体和多聚体复合物,其具有各种用途,无论何处治疗,检测,分离或定位血管发生都是有利的。 特别公开的是能够以高亲和力(例如具有KD <1μM)结合KDR或VEGF / KDR复合物的合成,分离的多肽,以及包含这些多肽的二聚体和多聚体构建体。
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公开(公告)号:US20080213251A1
公开(公告)日:2008-09-04
申请号:US11956792
申请日:2007-12-14
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/564 , G01N2800/122
摘要: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
摘要翻译: 本发明的特征在于hK1结合多肽以及包含这种多肽的组合物以及制备和使用这些多肽的方法。
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公开(公告)号:US08816055B2
公开(公告)日:2014-08-26
申请号:US13345170
申请日:2012-01-06
IPC分类号: A61K39/395 , C07K16/40 , A61K39/00
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/573 , G01N2333/96455 , G01N2500/04
摘要: Plasma kallikrein binding proteins and methods of using such proteins are described.
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公开(公告)号:US09359438B2
公开(公告)日:2016-06-07
申请号:US14122880
申请日:2012-06-01
CPC分类号: C07K16/283 , A61K39/3955 , A61K48/00 , A61K49/0002 , A61K2039/505 , C07K2317/565 , C07K2317/94 , G01N33/6854
摘要: The disclosure relates to antibodies that bind FcRn and methods of using these antibodies.
摘要翻译: 本公开涉及结合FcRn的抗体和使用这些抗体的方法。
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9.KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy 有权
标题翻译: KDR和VEGF / KDR结合肽及其在诊断和治疗中的应用公开(公告)号:US08642010B2
公开(公告)日:2014-02-04
申请号:US12480578
申请日:2009-06-08
申请人: Aaron K. Sato , Daniel J. Sexton , Daniel T. Dransfield , Robert C. Ladner , Christophe Arbogast , Philippe Bussat , Hong Fan , Sudha Khurana , Karen E. Linder , Edmund R. Marinelli , Palaniappa Nanjappan , Adrian D. Nunn , Radhakrishna K. Pillai , Sibylle Pochon , Feng Yan , Kondareddiar Ramalingam , Ajay Shrivastava , Bo Song , Rolf E. Swenson , Mathew A. Von Wronski
发明人: Aaron K. Sato , Daniel J. Sexton , Daniel T. Dransfield , Robert C. Ladner , Christophe Arbogast , Philippe Bussat , Hong Fan , Sudha Khurana , Karen E. Linder , Edmund R. Marinelli , Palaniappa Nanjappan , Adrian D. Nunn , Radhakrishna K. Pillai , Sibylle Pochon , Feng Yan , Kondareddiar Ramalingam , Ajay Shrivastava , Bo Song , Rolf E. Swenson , Mathew A. Von Wronski
CPC分类号: A61K49/221 , A61K38/00 , A61K47/62 , A61K49/223 , A61K51/088 , C07K7/08 , C07K14/001 , C07K14/52 , C07K14/71 , C07K2319/00 , Y02A50/411 , Y02A50/58
摘要: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD
摘要翻译: 本发明提供了包含用于KDR或VEGF / KDR复合物的至少一个结合部分的多肽,肽二聚体和多聚体复合物,其具有各种用途,无论何处治疗,检测,分离或定位血管发生都是有利的。 特别公开的是能够以高亲和力(例如具有KD <1μM)结合KDR或VEGF / KDR复合物的合成,分离的多肽,以及包含这些多肽的二聚体和多聚体构建体。
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公开(公告)号:US20110200611A1
公开(公告)日:2011-08-18
申请号:US12985914
申请日:2011-01-06
申请人: Daniel J. Sexton
发明人: Daniel J. Sexton
IPC分类号: A61K39/395 , C07K16/40 , A61P1/00 , A61P19/02 , A61P25/04 , A61P29/00 , A61P11/00 , A61P9/00
CPC分类号: C07K16/40 , A61K49/0004 , A61K2039/505 , C07K2317/76 , C07K2317/92
摘要: Plasma kallikrein binding proteins and methods of using such proteins are described.
摘要翻译: 描述了血浆激肽释放酶结合蛋白和使用这些蛋白质的方法。
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