Multiphase active ingredient formulation
    1.
    发明申请
    Multiphase active ingredient formulation 审中-公开
    多相活性成分配方

    公开(公告)号:US20070104795A1

    公开(公告)日:2007-05-10

    申请号:US10583302

    申请日:2004-12-15

    IPC分类号: A61K9/50 A61K9/16

    摘要: The invention relates to a formulation having a plurality of phases containing active ingredients. Said formulation is characterised in that: it contains a first, innermost, finely distributed phase (I) consisting of active ingredients or an active ingredient solution, preferably some of the phase particles being surrounded by a barrier sheath (M); the formulation has a second, intermediate phase (II) that serves as a dispersant for the first, inner phase (I) and can also be dissolved in the active ingredient; and the formulation has a third, outer phase (III) that serves as a dispersant for the second intermediate phase and can, in turn, be dissolved in the active ingredient and/or can be in the form of solid particles that can, in turn, be surrounded by a barrier sheath. In this way, a plurality of biological active ingredients can be produced in the different phases in different concentrations and with a respectively controlled release rate in a single formulation. According to the invention, a mechanical stabilisation is achieved by solidifying the intermediate phase (II) enabling the formulation to be stable for a longer period of time even once it has been applied to a surface. Furthermore, by selecting a suitable solvent for the outer phase, the formulations limit the release of the active ingredient from the innermost phase, and the capsules are not emptied and can thus be stored for a longer period of time.

    摘要翻译: 本发明涉及具有多个含有活性成分的相的制剂。 所述制剂的特征在于:其包含由活性成分或活性成分溶液组成的第一,最内部,细分布的相(I),优选一些相颗粒被阻挡护套(M)包围; 该制剂具有用作第一内相(I)的分散剂的第二中间相(II),也可以溶解在活性成分中; 并且该制剂具有用作第二中间相分散剂的第三个外相(III),并且可以依次被溶解在活性成分中和/或可以是固体颗粒的形式,反过来 ,被一个屏障护套包围。 以这种方式,可以在不同浓度的不同相中产生多种生物活性成分,并且可以在单一制剂中分别控制释放速率。 根据本发明,通过固化中间相(II)来实现机械稳定化,使得制剂即使一旦施加到表面上也能够更长时间地稳定。 此外,通过为外相选择合适的溶剂,制剂限制活性成分从最内层的释放,并且胶囊不会排空,因此可以储存较长时间。

    PHYLLOSILICATE FORMULATIONS FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES
    4.
    发明申请
    PHYLLOSILICATE FORMULATIONS FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES 审中-公开
    用于控制释放活性物质的硅藻土配方

    公开(公告)号:US20090170705A1

    公开(公告)日:2009-07-02

    申请号:US12160688

    申请日:2007-01-12

    IPC分类号: A01N25/12 A61K47/00 A61K8/02

    CPC分类号: C01B33/44 A01N25/08 A01N25/12

    摘要: Novel seed dressing agent formulations comprising of—at least one active agrochemical ingredient for the dressing of seeds, —a dispersion of biologically degradable polyester-polyurethane-polyureas in water whereby the solid content thereof is between 30 and 50 weight %. Said formulation also comprises additives. The invention also relates to a method for the production of a novel seed dressing agent formulation and the utilization thereof for the dressing of seeds.

    摘要翻译: 包含至少一种用于种子种植的活性农药组分的新型拌种剂制剂, - 生物可降解聚酯 - 聚氨酯 - 聚脲在水中的分散体,其中固体含量为30-50重量%。 所述制剂还包含添加剂。 本发明还涉及一种生产新型拌种剂制剂的方法及其用于种子种植的方法。