专利检索 ap:("Danwei Huangfu" OR "Douglas A. Melton" OR "Rene Maehr") AND inv:"Danwei Huangfu" 第 1 页

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发明申请
EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS 审中-公开
标题翻译：使用小分子化合物有效诱导大脑干细胞

公开(公告)号：US20110014164A1

公开(公告)日：2011-01-20

申请号：US12867615

申请日：2009-02-13

申请人： Danwei Huangfu , Douglas A. Melton , Rene Maehr

发明人： Danwei Huangfu , Douglas A. Melton , Rene Maehr

IPC分类号： A61K35/12 , C12N5/07 , C12N5/0797 , C12N5/071 , G01N33/566 , A61P25/28 , A61P17/02 , A61P9/00 , A61P9/10 , A61P1/16 , A61P3/10 , A61P5/14 , A61P11/00 , A61P19/08 , A61P35/02 , A61P37/02 , A61P7/06

CPC分类号： C12N5/0696 , C12N2501/065 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2510/00

摘要： The disclosure features a method of producing an induced pluripotent stem cell a somatic cell. The method includes contacting a somatic cell with a DNA methyl transferase inhibitor or a histone deacetylase (HDAC) inhibitor, or a combination thereof, to produce a pluripotent stem cell.

摘要翻译： 本公开特征在于产生诱导多能干细胞体细胞的方法。该方法包括使体细胞与DNA甲基转移酶抑制剂或组蛋白脱乙酰酶（HDAC）抑制剂或其组合接触以产生多能干细胞。