公开(公告)号：US08512360B2

公开(公告)日：2013-08-20

申请号：US10778723

申请日：2004-02-13

申请人： A. Adam Sharkawy ,  Dean F. Carson ,  Darin C. Gittings ,  Keke J. Lepulu ,  Mark J. Foley ,  Wally S. Buch ,  Alan R. Rapacki

发明人： A. Adam Sharkawy ,  Dean F. Carson ,  Darin C. Gittings ,  Keke J. Lepulu ,  Mark J. Foley ,  Wally S. Buch ,  Alan R. Rapacki

IPC分类号： A61B17/08 ,  A61M5/00

CPC分类号： A61F2/94 ,  A61B17/11 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2018/00392 ,  A61F2/064 ,  A61F2/24 ,  A61F2/2493 ,  A61F2002/30079 ,  A61F2210/009 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0058 ,  A61F2230/0076

摘要： Methods and devices for placing a target vessel in fluid communication with a source of blood and a target vessel. A conduit includes first portion adapted to be placed in fluid communication with a source of blood, such as a heart chamber, and a second portion adapted to be placed in fluid communication with a target vessel having a lumen, such as coronary artery. The first and second conduit portions are transverse to each other such that the conduit is generally T-shaped. The conduit lies on an exterior of the heart between the blood source and the target vessel and is configured to deliver blood in multiple directions into the lumen of the target vessel. For example, in an occluded coronary artery, blood flows both toward and away from the occlusion. The conduit may be flexible, rigid, collapsible or non-collapsible, and may be formed of synthetic vascular graft material, tissue, or a combination of the two. A conduit delivery device is disclosed for deploying the conduit in a target vessel and perfusing the vessel during such deployment.

摘要翻译： 用于放置目标血管与血液源和靶血管流体连通的方法和装置。 导管包括适于与诸如心脏腔的血液源流体连通的第一部分和适于与具有诸如冠状动脉的内腔的靶血管流体连通的第二部分。 第一和第二导管部分彼此横向，使得导管通常为T形。 导管位于血液源和目标血管之间的心脏外部，并被构造成将多个方向的血液输送到目标血管的内腔中。 例如，在闭塞的冠状动脉中，血液朝向和远离闭塞流动。 导管可以是柔性的，刚性的，可收缩的或不可折叠的，并且可以由合成的血管移植物材料，组织或两者的组合形成。 公开了一种导管输送装置，用于将导管部署在靶容器中并且在这种部署期间灌注容器。

公开(公告)号：US07578828B2

公开(公告)日：2009-08-25

申请号：US10441256

申请日：2003-05-19

申请人： Darin C. Gittings ,  Alan R. Rapacki ,  Dean F. Carson ,  David H. Cole ,  Keke Lepulu ,  Adam Sharkawy ,  Gilbert S. Laroya ,  Wally S. Buch

发明人： Darin C. Gittings ,  Alan R. Rapacki ,  Dean F. Carson ,  David H. Cole ,  Keke Lepulu ,  Adam Sharkawy ,  Gilbert S. Laroya ,  Wally S. Buch

IPC分类号： A61B17/08

CPC分类号： A61F2/95 ,  A61B17/11 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/00867 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1205 ,  A61B2017/2923 ,  A61F2/064 ,  A61F2/07 ,  A61F2/86 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/9517 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054

摘要： Methods and devices for placing a conduit in fluid communication with a target vessel and a source of blood, such as the aorta or a heart chamber. The device may be actuated using one hand to place the conduit. The invention allows air in the conduit to be removed prior to placement of the conduit. The invention deploys the conduit in the target vessel by moving a sheath in a distal direction and then in a proximal direction. A conduit is provided with a reinforcing member to prevent kinking of the conduit, and a structure for preventing blockage of the conduit by tissue. A vessel coupling may be used to secure a conduit to a target vessel so as to preserve native blood flow through the vessel, and the conduit may be placed in fluid communication with a target vessel via a laparoscopic or endoscopic procedure.

公开(公告)号：US20090005852A1

公开(公告)日：2009-01-01

申请号：US12179943

申请日：2008-07-25

申请人： Darin C. Gittings ,  Alan R. Rapacki ,  Adam Sharkawy ,  Wally S. Buch

发明人： Darin C. Gittings ,  Alan R. Rapacki ,  Adam Sharkawy ,  Wally S. Buch

IPC分类号： A61F2/84 ,  A61M1/00 ,  A61F2/06

CPC分类号： A61F2/95 ,  A61B17/11 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/00867 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1205 ,  A61B2017/2923 ,  A61F2/064 ,  A61F2/07 ,  A61F2/86 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/9517 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054

摘要： Methods and devices for placing a conduit in fluid communication with a target vessel and a source of blood, such as the aorta or a heart chamber. The device may be actuated using one hand to place the conduit. The invention allows air in the conduit to be removed prior to placement of the conduit. The invention deploys the conduit in the target vessel by moving a sheath in a distal direction and then in a proximal direction. A conduit is provided with a reinforcing member to prevent kinking of the conduit, and a structure for preventing blockage of the conduit by tissue. A vessel coupling may be used to secure a conduit to a target vessel so as to preserve native blood flow through the vessel, and the conduit may be placed in fluid communication with a target vessel via a laparoscopic or endoscopic procedure.

摘要翻译： 用于放置导管与靶血管和血液源（例如主动脉或心室）流体连通的方法和装置。 可以使用一只手来致动装置以放置导管。 本发明允许导管内的空气在放置导管之前被去除。 本发明通过在远端方向上移动护套然后在近端方向上将导管部署在靶容器中。 导管设置有加强构件以防止导管的扭结，以及用于防止组织堵塞导管的结构。 可以使用血管联接器将导管固定到靶容器，以便保持通过血管的天然血液流动，并且可以通过腹腔镜或内窥镜程序使导管与靶血管流体连通。

公开(公告)号：US07025773B2

公开(公告)日：2006-04-11

申请号：US09850883

申请日：2001-05-07

申请人： Darin C. Gittings ,  Alan R. Rapacki ,  Dean F. Carson ,  David H. Cole ,  Keke Lepulu ,  Adam Sharkawy ,  Gilbert S. Laroya ,  Wally S. Buch

发明人： Darin C. Gittings ,  Alan R. Rapacki ,  Dean F. Carson ,  David H. Cole ,  Keke Lepulu ,  Adam Sharkawy ,  Gilbert S. Laroya ,  Wally S. Buch

IPC分类号： A61B17/08

CPC分类号： A61F2/915 ,  A61B17/11 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/00867 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/2923 ,  A61F2/064 ,  A61F2/07 ,  A61F2/86 ,  A61F2/91 ,  A61F2/95 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/9517 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0058 ,  A61F2230/0067 ,  A61F2230/0076

摘要： Methods and devices for placing a conduit in fluid communication with a target vessel and a source of blood, such as the aorta or a heart chamber. The device may be actuated using one hand to place the conduit. The invention allows air in the conduit to be removed prior to placement of the conduit. The invention deploys the conduit in the target vessel by moving a sheath in a distal direction and then in a proximal direction. A conduit is provided with a reinforcing member to prevent kinking of the conduit, and a structure for preventing blockage of the conduit by tissue. A vessel coupling may be used to secure a conduit to a target vessel so as to preserve native blood flow through the vessel, and the conduit may be placed in fluid communication with a target vessel via a laparoscopic or endoscopic procedure.

公开(公告)号：US06517558B2

公开(公告)日：2003-02-11

申请号：US09776230

申请日：2001-02-01

申请人： Darin C. Gittings ,  Wally S. Buch ,  Alan R. Rapacki

发明人： Darin C. Gittings ,  Wally S. Buch ,  Alan R. Rapacki

IPC分类号： A61B1702

CPC分类号： A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/064 ,  A61F2/07 ,  A61F2/86 ,  A61F2/91

摘要： Methods and devices for forming an anastomosis utilize a graft vessel secured to a vessel coupling that is fixed to a target vessel without using suture. The vessel coupling may be collapsed for introduction into the target vessel and then expanded to engage the vessel wall. The vessel coupling may be a stent attached to a graft vessel to form a stent-graft assembly. The anastomosis may be carried out to place the graft and target vessels in fluid communication while preserving native proximal flow through the target vessel, which may be a coronary artery. As a result, blood flowing through the coronary artery from the aorta is not blocked by the vessel coupling and thus is free to move past the site of the anastomosis.

摘要翻译： 用于形成吻合的方法和装置利用固定到血管联接的移植血管，所述移植血管在不使用缝合线的情况下固定到靶血管。 血管联接器可能被塌缩以引入目标血管，然后膨胀以接合血管壁。 血管联接可以是附接到移植血管以形成支架移植物组件的支架。 可以进行吻合以使移植物和靶容器保持流体连通，同时保持通过可能是冠状动脉的靶血管的天然近端流。 结果，从主动脉流过冠状动脉的血液不被血管联接阻塞，因此可以自由地移动通过吻合部位。

公开(公告)号：US07137962B2

公开(公告)日：2006-11-21

申请号：US10011630

申请日：2001-10-22

申请人： Darin C. Gittings ,  A. Adam Sharkawy ,  Alan R. Rapacki ,  Gilbert S. Laroya

发明人： Darin C. Gittings ,  A. Adam Sharkawy ,  Alan R. Rapacki ,  Gilbert S. Laroya

IPC分类号： A61N5/00 ,  A61F2/04

CPC分类号： A61F2/94 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61F2/24 ,  A61F2/2493 ,  A61F2/82 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0091 ,  A61F2250/0007

摘要： Devices and methods utilized in performing transmyocardial coronary bypass include retractors used to engage and support myocardial tissue, and mechanisms for supporting coronary vessels so as to allow precise entry into a vessel lumen. In addition, various conduits are provided having a configuration that permits their positioning in a heart wall to place a coronary vessel in communication with a heart chamber.

公开(公告)号：US20120004589A1

公开(公告)日：2012-01-05

申请号：US13187070

申请日：2011-07-20

申请人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

发明人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

IPC分类号： A61F2/06

CPC分类号： A61F2/064 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61B2090/062 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/94 ,  A61F2/966 ,  A61F2002/30079 ,  A61F2002/30617 ,  A61F2002/9517 ,  A61F2210/009 ,  A61F2250/0097

摘要： Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.

摘要翻译： 将导管输送到患者心脏的壁中以将冠状动脉血管与心脏腔室通信的装置和方法。 装置通过冠状血管和心脏壁以放置导管，并在容器和心脏腔室之间建立血流路径。 提供了附加的装置和方法，用于从冠状血管或心脏壁去除组织，以建立与心室连通的冠状血管之间的流动路径。

公开(公告)号：US06651670B2

公开(公告)日：2003-11-25

申请号：US09170994

申请日：1998-10-13

申请人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

发明人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

IPC分类号： A61B1700

CPC分类号： A61F2/064 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61B2090/062 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/94 ,  A61F2/966 ,  A61F2002/30079 ,  A61F2002/30617 ,  A61F2002/9517 ,  A61F2210/009 ,  A61F2250/0097

摘要： Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.

摘要翻译： 将导管输送到患者心脏的壁中以将冠状动脉血管与心脏腔室通信的装置和方法。 装置通过冠状血管和心脏壁以放置导管，并在容器和心脏腔室之间建立血流路径。 提供了附加的装置和方法，用于从冠状血管或心脏壁去除组织，以在与心室连通的冠状血管之间建立流路。

公开(公告)号：US07993356B2

公开(公告)日：2011-08-09

申请号：US11540703

申请日：2006-09-29

申请人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

发明人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

IPC分类号： A61B17/08

CPC分类号： A61F2/064 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61B2090/062 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/94 ,  A61F2/966 ,  A61F2002/30079 ,  A61F2002/30617 ,  A61F2002/9517 ,  A61F2210/009 ,  A61F2250/0097

摘要： Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.

摘要翻译： 将导管输送到患者心脏的壁中以将冠状动脉血管与心脏腔室通信的装置和方法。 装置通过冠状血管和心脏壁以放置导管，并在容器和心脏腔室之间建立血流路径。 提供了附加的装置和方法，用于从冠状血管或心脏壁去除组织，以建立与心室连通的冠状血管之间的流动路径。

公开(公告)号：US07214234B2

公开(公告)日：2007-05-08

申请号：US10441257

申请日：2003-05-19

申请人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

发明人： Alan R. Rapacki ,  Darin C. Gittings ,  Gilbert S. Laroya ,  Mark J. Foley

IPC分类号： A61B17/32 ,  A61B17/34 ,  A61N1/00

CPC分类号： A61F2/064 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61B2090/062 ,  A61F2/2493 ,  A61F2/90 ,  A61F2/94 ,  A61F2/966 ,  A61F2002/30079 ,  A61F2002/30617 ,  A61F2002/9517 ,  A61F2210/009 ,  A61F2250/0097

摘要： Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.