Brain Stimulation models, systems, devices, and methods
    9.
    发明申请
    Brain Stimulation models, systems, devices, and methods 有权
    脑刺激模型,系统,设备和方法

    公开(公告)号:US20080114579A1

    公开(公告)日:2008-05-15

    申请号:US12008760

    申请日:2008-01-14

    IPC分类号: G06G7/60

    摘要: This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence. In another example, a neuron or axon model is used to calculate the volume of influence without computing the second difference of the electric potential distribution.

    摘要翻译: 本文件还讨论了脑刺激模型,系统,设备和方法,例如深部脑刺激(DBS)或其他电刺激。 模型使用某些刺激参数(如幅度,脉冲宽度,频率,脉冲形态,电极接触选择或位置,返回路径电极选择,脉冲极性等)来计算模拟电刺激的影响区域的体积。该模型使用非 - 组织电导率不均匀。 这准确地表示脑组织,其具有产生非均匀和各向异性的组织培养基的高度定向导电的神经元途径。 在一个示例中,从扩散张量成像(DTI)数据获得非均匀组织电导率。 在一个示例中,电位分布的第二差异用于定义激活量(VOA)或类似的影响体积。 在另一个例子中,使用神经元或轴突模型来计算影响的体积,而不计算电势分布的第二差异。