公开(公告)号：US07813694B2

公开(公告)日：2010-10-12

申请号：US12038519

申请日：2008-02-27

申请人： David A Fishman ,  Raymond K Jones ,  Eric Zhong

发明人： David A Fishman ,  Raymond K Jones ,  Eric Zhong

IPC分类号： H04H20/71 ,  H04H40/00 ,  H04B7/185

CPC分类号： H04H20/33 ,  H04H20/106 ,  H04H20/26 ,  H04H20/74 ,  H04H40/90 ,  H04H60/21 ,  H04H2201/19 ,  H04H2201/40

摘要： A secondary satellite radio or broadcast channel is used to broadcast advertisement clips (e.g., audio clips) to a receiver for subsequent decoding and playback. The receiver is configured for different tiers of service, e.g., one that delivers substantially advertising-free content and another that delivers content that includes more significant amounts of advertising. The content delivered to both is the same content; however, for the service tier that includes more advertising, the advertisements broadcast on the secondary channel are interleaved into the content, preferably in such a way that the continuity of the content being delivered is not compromised.

摘要翻译： 辅助卫星广播或广播频道用于将广播片段（例如，音频剪辑）广播到接收机以用于随后的解码和重放。 接收器被配置用于不同的服务层，例如提供实质上无广告的内容的接收器，另一个传送包括更多大量广告的内容。 提供给两者的内容是相同的内容; 然而，对于包括更多广告的服务层，在辅助信道上广播的广告被交织到内容中，优选地以这样一种方式使得被传递的内容的连续性不受影响。

公开(公告)号：US20080163291A1

公开(公告)日：2008-07-03

申请号：US12038519

申请日：2008-02-27

申请人： David A. Fishman ,  Raymond K. Jones ,  Eric Zhong

发明人： David A. Fishman ,  Raymond K. Jones ,  Eric Zhong

IPC分类号： H04N7/00

CPC分类号： H04H20/33 ,  H04H20/106 ,  H04H20/26 ,  H04H20/74 ,  H04H40/90 ,  H04H60/21 ,  H04H2201/19 ,  H04H2201/40

摘要： A secondary satellite radio or broadcast channel is used to broadcast advertisement clips (e.g., audio clips) to a receiver for subsequent decoding and playback. The receiver is configured for different tiers of service, e.g., one that delivers substantially advertising-free content and another that delivers content that includes more significant amounts of advertising. The content delivered to both is the same content; however, for the service tier that includes more advertising, the advertisements broadcast on the secondary channel are interleaved into the content, preferably in such a way that the continuity of the content being delivered is not compromised.

摘要翻译： 辅助卫星广播或广播频道用于将广播片段（例如，音频剪辑）广播到接收机以用于随后的解码和重放。 接收器被配置用于不同的服务层，例如提供实质上无广告的内容的接收器，另一个传送包括更多大量广告的内容。 提供给两者的内容是相同的内容; 然而，对于包括更多广告的服务层，在辅助信道上广播的广告被交织到内容中，优选地以这样一种方式使得被传递的内容的连续性不受影响。

公开(公告)号：US07363000B2

公开(公告)日：2008-04-22

申请号：US10717728

申请日：2003-11-20

申请人： David A. Fishman ,  Raymond K. Jones ,  Eric Zhong

发明人： David A. Fishman ,  Raymond K. Jones ,  Eric Zhong

IPC分类号： H04H1/00 ,  H04Q7/20 ,  H04B7/185

CPC分类号： H04H20/33 ,  H04H20/106 ,  H04H20/26 ,  H04H20/74 ,  H04H40/90 ,  H04H60/21 ,  H04H2201/19 ,  H04H2201/40

摘要： A secondary satellite radio or broadcast channel is used to broadcast advertisement clips (e.g., audio clips) to a receiver for subsequent decoding and playback. The receiver is configured for different tiers of service, e.g., one that delivers substantially advertising-free content and another that delivers content that includes more significant amounts of advertising. The content delivered to both is the same content; however, for the service tier that includes more advertising, the advertisements broadcast on the secondary channel are interleaved into the content, preferably in such a way that the continuity of the content being delivered is not compromised.

摘要翻译： 辅助卫星广播或广播频道用于将广播片段（例如，音频片段）广播到接收机以用于随后的解码和重放。 接收器被配置用于不同的服务层，例如提供实质上无广告的内容的接收器，另一个传送包括更多大量广告的内容。 提供给两者的内容是相同的内容; 然而，对于包括更多广告的服务层，在辅助信道上广播的广告被交织到内容中，优选地以这样一种方式使得被传递的内容的连续性不受影响。

公开(公告)号：US07415259B2

公开(公告)日：2008-08-19

申请号：US10876041

申请日：2004-06-24

申请人： David A. Fishman ,  Robert C. Malkemes ,  Denis P. Orlando ,  Jie Song ,  Eric Zhong ,  Ying Zhu

发明人： David A. Fishman ,  Robert C. Malkemes ,  Denis P. Orlando ,  Jie Song ,  Eric Zhong ,  Ying Zhu

IPC分类号： H04B1/06

CPC分类号： H03G3/3078 ,  H03G3/3052 ,  H04B7/18523 ,  H04H40/90

摘要： An automatic gain control (AGC) for a Satellite Digital Audio Radio Service (SDARS) receiver, a method of automatically controlling gain and a SDARS receiver incorporating the AGC or the method. In one embodiment, the AGC includes: (1) an AGC function selector configured to compare first and second time division multiplexed (TDM) power signals and a nonzero threshold and select an AGC function based thereon and (2) an AGC function applier associated with the AGC function selector and configured to apply the AGC function to the first and second TDM power signals to develop therefrom an AGC control signal.

摘要翻译： 用于卫星数字音频无线电服务（SDARS）接收机的自动增益控制（AGC），自动控制增益的方法和包含AGC或方法的SDARS接收机。 在一个实施例中，AGC包括：（1）AGC功能选择器，被配置为比较第一和第二时分复用（TDM）功率信号和非零阈值，并且基于此选择AGC功能;以及（2）AGC功能选择器， 所述AGC功能选择器被配置为将AGC功能应用于所述第一和第二TDM功率信号以从其开发AGC控制信号。

公开(公告)号：US07899624B2

公开(公告)日：2011-03-01

申请号：US11492167

申请日：2006-07-25

申请人： Hernani Del Mundo Cualing ,  Eric Zhong

发明人： Hernani Del Mundo Cualing ,  Eric Zhong

IPC分类号： G06F19/00 ,  G06K9/52

CPC分类号： G01N33/56966 ,  G01N33/57492

摘要： An automated method for rapidly analyzing percentage of positive cells from immunostained tissue sections is disclosed. The method is an improved multi-stage dynamic thresholding series of steps applied to monochromatic gray-scale values of color channels of digital image of tissue. The method requires color digital images of tissue. The method discloses sequential stages to obtain a step-wise progression of preliminary image planes iteratively combined to obtain a final immunostained and non-immunostained images of cells of the same cell class. The final results are segmented cells that are digitally countable. The percent of immunostained cells over the total cells are calculated in tissue section. The cell characteristics, including cell size and its immunostaining intensity are captured and digitally stored per cell. The segmented single cell color image as well as the corresponding cell characteristic are displayed as a dot plot two-dimensional flow cytometry-like manner.

摘要翻译： 公开了一种用于快速分析来自免疫染色组织切片的阳性细胞百分比的自动化方法。 该方法是应用于组织数字图像的彩色通道的单色灰度值的改进的多阶段动态阈值系列步骤。 该方法需要组织的彩色数字图像。 该方法公开了顺序阶段，以获得迭代组合的初步影像的逐步进展，以获得相同细胞类别的细胞的最终免疫染色和非免疫染色图像。 最终结果是可数字计数的分段单元格。 在组织切片中计算出总细胞中免疫染色细胞的百分数。 细胞特征，包括细胞大小和免疫染色强度被捕获并且每个细胞数字储存。 分段的单细胞彩色图像以及相应的细胞特征被显示为二维流式细胞仪的点图。

公开(公告)号：US09607372B2

公开(公告)日：2017-03-28

申请号：US12668628

申请日：2008-07-11

申请人： Hernani D. Cualing ,  Eric Zhong

发明人： Hernani D. Cualing ,  Eric Zhong

IPC分类号： G06K9/00 ,  G06T7/00

CPC分类号： G06T7/0012 ,  G06K9/0014 ,  G06T2207/10056 ,  G06T2207/30024

摘要： The invention determines cell to fat ratio statistic, applicable in the field of pathology, in a greatly improved manner over manual or prior art scoring techniques. The cellular areas are identified and displayed in an easy to read format on the computer monitor, printer output or other display means, with average cellularity, nuclear quantity distribution at a glance. These output data are an objective transformation of the subjective visible image that the pathologist or scientist relies upon for diagnosis, prognosis, or monitoring therapeutic perturbations. The invention uses multi-stage thresholding and segmentation algorithms in RGB and HSB spaces, auto-thresholding on red and blue channels in RGB to get the raw working image of all cells, then refines the working image with thresholding on hue and intensity channels in HSB using an adaptive parameter epsilon in entropy mode, and further separates different groups of cells within the same class, by auto-thresholding within the working image region.

公开(公告)号：US20050202808A1

公开(公告)日：2005-09-15

申请号：US10993303

申请日：2004-11-19

申请人： David Fishman ,  Raymond Jones ,  Anthony Stillwell ,  Eric Zhong

发明人： David Fishman ,  Raymond Jones ,  Anthony Stillwell ,  Eric Zhong

IPC分类号： H04M3/00

CPC分类号： H04L67/34 ,  H04B7/18578 ,  H04H20/91 ,  H04H60/25

摘要： A content channel is periodically or permanently allocated for use as an “update channel” or “firmware-image download” channel. Any firmware images downloaded to receivers in the system are thoroughly tested prior to being distributed among the receivers. Header information is included in the firmware image when it is transmitted to the receivers, and the firmware image is not accepted for use by the receivers until it is verified on the receiver side. Further, rather than overwriting the existing firmware, the new validated firmware updates are stored separately on the receivers and are utilized when the receiver is rebooted during power-up or by the host controller. If, during this reboot process, an error occurs in the new firmware image, the receiver is configured to revert back to the original firmware image so that it will remain operational, albeit without the updated firmware features.

摘要翻译： 定期或永久地分配内容频道以用作“更新频道”或“固件图像下载”频道。 下载到系统中的接收器的任何固件映像在被分配在接收器之前被彻底测试。 当固件图像被发送到接收器时，标题信息被包括在固件图像中，并且固件图像在接收器侧被验证之前不被接收器使用。 此外，新的经过验证的固件更新不是重写现有固件，而是单独存储在接收器上，并且在上电期间或由主机控制器重新启动接收机时被使用。 如果在此重新启动过程中，新固件映像中出现错误，则接收器将配置为恢复为原始固件映像，以使其保持运行，尽管没有更新的固件功能。

公开(公告)号：US20070041481A1

公开(公告)日：2007-02-22

申请号：US11204631

申请日：2005-08-16

申请人： Robert Malkemes ,  Denis Orlando ,  Jie Song ,  Eric Zhong

发明人： Robert Malkemes ,  Denis Orlando ,  Jie Song ,  Eric Zhong

IPC分类号： H04L27/08

CPC分类号： H03G3/3052 ,  H03G1/0088 ,  H04H20/22 ,  H04H40/90

摘要： An automatic gain control (AGC) for use in a digital radio receiver that allows at least two types of input signal to be processed using a single receiver front end by supporting two modes of operation, each optimized for one particular signal type, and a third mode not optimized for either. The AGC enables smooth switching between the optimized modes of operation via the non-optimized mode. By measuring a difference in the strength between the demodulated signals, and comparing that to two preset values, the AGC which mode of operation to place the receiver in. Modes of operation are maintained by adjusting the gain of a variable gain amplifier (VGA), so that an appropriate incoming signal is amplified to a level that is suitable for an analogue-to-digital (ADC) converter. The AGC is compatible with existing satellite digital audio radio system (SDARS) transmission capabilities.

摘要翻译： 一种在数字无线电接收机中使用的自动增益控制（AGC），其允许使用单个接收器前端来处理至少两种类型的输入信号，所述两个接收机前端通过支持针对一种特定信号类型优化的两种操作模式，以及第三种 模式未优化。 AGC可以通过非优化模式在优化的操作模式之间平滑切换。 通过测量解调信号之间的强度差，并将其与两个预设值进行比较，AGC将接收器放置在操作模式中。通过调节可变增益放大器（VGA）的增益来维持操作模式， 使得适当的输入信号被放大到适合于模数（ADC）转换器的电平。 AGC与现有的卫星数字音频无线电系统（SDARS）传输能力相兼容。

公开(公告)号：US20070020697A1

公开(公告)日：2007-01-25

申请号：US11492167

申请日：2006-07-25

申请人： Hernani Cualing ,  Eric Zhong

发明人： Hernani Cualing ,  Eric Zhong

IPC分类号： G01N33/567 ,  G06F19/00 ,  C12M3/00

CPC分类号： G01N33/56966 ,  G01N33/57492

摘要： The invention provides an automated method of single cell image analysis which determines cell population statistic, applicable in the field of pathology, disease or cancer diagnosis, in a greatly improved manner over manual or prior art scoring techniques. By combining the scientific advantages of computerized automation and the invented method, as well as the greatly increased speed with which population can be evaluated, the invention is a major improvement over methods currently available. The single cells are identified and displayed in an easy to read format on the computer monitor, printer output or other display means, with cell parameter such as cell size and staining distribution at a glance. These output data is an objective transformation of the subjective visible image that the pathologist or scientist relies upon for diagnosis, prognosis, or monitoring therapeutic perturbations. Using our novel proposed technology, we combine the advantages provided by the clinical standard tool of flow cytometry in quantifying single cells and also retain the advantages of microscopy in retaining the capability of visualizing the immunoreactive cells. Unlike flow cytometry however, the invention uses commonly available formalin fixed immunostained tissue and not fresh viable cells. To accomplish this aim, we resort to new and improved advanced image analysis using a unique, useful, and adaptive process as described herein. The method uses multi-stage thresholding and segmentation algorithm based on multiple color channels in RGB and HS I spaces and uses auto-thresholding on red and blue channels in RGB to get the raw working image of all cells, then refines the working image with thresholding on hue and intensity channels in HS I using an adaptive parameter epsilon in entropy mode, and further separates different groups of cells within the same class, by auto-thresholding within the working image region. The Immunohistochemistry Flow cytometry (IHCFLOW) combination results in a new paradigm that is both useful, novel, and provides objective tangible result from a complex color image of tissue.

公开(公告)号：US20050287975A1

公开(公告)日：2005-12-29

申请号：US10876041

申请日：2004-06-24

申请人： David Fishman ,  Robert Malkemes ,  Denis Orlando ,  Jie Song ,  Eric Zhong ,  Ying Zhu

发明人： David Fishman ,  Robert Malkemes ,  Denis Orlando ,  Jie Song ,  Eric Zhong ,  Ying Zhu

IPC分类号： H03G3/20 ,  H03G3/30 ,  H04B1/06 ,  H04B7/00 ,  H04H1/00 ,  H04H40/90 ,  H04L27/08

CPC分类号： H03G3/3078 ,  H03G3/3052 ,  H04B7/18523 ,  H04H40/90

摘要： An automatic gain control (AGC) for a Satellite Digital Audio Radio Service (SDARS) receiver, a method of automatically controlling gain and a SDARS receiver incorporating the AGC or the method. In one embodiment, the AGC includes: (1) an AGC function selector configured to compare first and second time division multiplexed (TDM) power signals and a nonzero threshold and select an AGC function based thereon and (2) an AGC function applier associated with the AGC function selector and configured to apply the AGC function to the first and second TDM power signals to develop therefrom an AGC control signal.

摘要翻译： 用于卫星数字音频无线电服务（SDARS）接收机的自动增益控制（AGC），自动控制增益的方法和包含AGC或方法的SDARS接收机。 在一个实施例中，AGC包括：（1）AGC功能选择器，被配置为比较第一和第二时分复用（TDM）功率信号和非零阈值，并且基于此选择AGC功能;以及（2）AGC功能选择器， 所述AGC功能选择器被配置为将AGC功能应用于所述第一和第二TDM功率信号以从其开发AGC控制信号。