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公开(公告)号：US07927870B2
公开(公告)日：2011-04-19
申请号：US11431676
申请日：2006-05-10
申请人： David B. Volkin , Robert K. Evans , Mark Bruner
发明人： David B. Volkin , Robert K. Evans , Mark Bruner
CPC分类号： A61K9/0019 , A61K39/12 , A61K39/145 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K48/00 , A61K2039/53 , C12N15/1003 , C12N2760/16111 , C12N2760/16134
摘要： This invention relates to novel methods and formulations of nucleic acid pharmaceutical products, specifically formulations of nucleic acid vaccine products and nucleic acid gene therapy products. The formulations of the disclosure stabilize the conformation of DNA pharmaceutical products.
摘要翻译： 本发明涉及核酸药物产品的新方法和制剂，特别是核酸疫苗产品和核酸基因治疗产品的制剂。 本公开的制剂稳定了DNA药物产品的构象。
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公开(公告)号：US20060217341A1
公开(公告)日：2006-09-28
申请号：US11431676
申请日：2006-05-10
申请人： David Volkin , Robert Evans , Mark Bruner
发明人： David Volkin , Robert Evans , Mark Bruner
CPC分类号： A61K9/0019 , A61K39/12 , A61K39/145 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K48/00 , A61K2039/53 , C12N15/1003 , C12N2760/16111 , C12N2760/16134
摘要： This invention relates to novel methods and formulations of nucleic acid pharmaceutical products, specifically formulations of nucleic acid vaccine products and nucleic acid gene therapy products. The formulations of the disclosure stabilize the conformation of DNA pharmaceutical products.
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