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公开(公告)号：US20080021059A1
公开(公告)日：2008-01-24
申请号：US11576538
申请日：2005-09-23
申请人： David Butler , Huifen Chen , Vishnumurthy Hegde , Chris Limberakis , Ravindra Rasne , Richard Sciotti , Jeremy Starr
发明人： David Butler , Huifen Chen , Vishnumurthy Hegde , Chris Limberakis , Ravindra Rasne , Richard Sciotti , Jeremy Starr
IPC分类号： C07D471/04 , A61K31/437 , A61P31/04
CPC分类号： C07D471/04
摘要： The present invention is directed to a new class of triazolopyridine derivatives, to their use as antimicrobials, and to pharmaceuticals containing these compounds.
摘要翻译： 本发明涉及新一类三唑并吡啶衍生物，其用作抗微生物剂，以及含有这些化合物的药物。
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公开(公告)号：US20110165699A1
公开(公告)日：2011-07-07
申请号：US13039868
申请日：2011-03-03
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Hongxia Zhang , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Hongxia Zhang , Howard Sard , Vishnumurthy Hegde
IPC分类号： G01N33/98 , C07K16/44 , C07D491/22 , C07K2/00 , B82Y15/00
CPC分类号： C07D491/22 , C07K16/44 , G01N33/536 , G01N33/577
摘要： Novel conjugates of the pharmaceutically active metabolite of irinotecan and novel immunogens derived from this pharmaceutically active metabolite and monoclonal antibodies generated by these immunogens which are useful in immunoassays for the quantification and monitoring of the pharmaceutically active metabolite of irinotecan in biological fluids.
摘要翻译： 伊立替康的药学活性代谢物和由这些免疫原产生的这种药物活性代谢物和单克隆抗体的新型免疫原的新型缀合物，其可用于定量和监测生物流体中伊立替康的药学活性代谢物的免疫测定。
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公开(公告)号：US20130245241A1
公开(公告)日：2013-09-19
申请号：US13873444
申请日：2013-04-30
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
IPC分类号： C07K14/00 , C07D471/04
CPC分类号： C07K14/001 , C07D471/04 , C07K16/44 , G01N33/94 , Y10S436/815
摘要： Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids.
摘要翻译： 衍生自利培酮和由这些免疫原产生的抗体的新型缀合物和免疫原可用于免疫测定用于定量和监测生物液体中的利培酮和帕培酮。
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公开(公告)号：US08293492B2
公开(公告)日：2012-10-23
申请号：US13302844
申请日：2011-11-22
申请人： Salvatore J Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
IPC分类号： G01N33/53 , G01N33/543 , C07K1/10
CPC分类号： C07K16/44 , C07D401/04 , C07D401/14 , G01N33/5308 , G01N33/9453 , Y10S436/815
摘要： Novel conjugates and immunogens derived from lenalidomide and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of thalidomide and lenalidomide in biological fluids.
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公开(公告)号：US08088594B2
公开(公告)日：2012-01-03
申请号：US12724780
申请日：2010-03-16
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
IPC分类号： G01N33/53 , G01N33/543 , C07K1/10
CPC分类号： C07K14/001 , C07D471/04 , C07K16/44 , G01N33/94 , Y10S436/815
摘要： Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids.
摘要翻译： 衍生自利培酮和由这些免疫原产生的抗体的新型缀合物和免疫原可用于免疫测定用于定量和监测生物液体中的利培酮和帕培酮。
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公开(公告)号：US20110229979A1
公开(公告)日：2011-09-22
申请号：US12724780
申请日：2010-03-16
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
IPC分类号： G01N33/53 , C07K16/18 , C07D471/04
CPC分类号： C07K14/001 , C07D471/04 , C07K16/44 , G01N33/94 , Y10S436/815
摘要： Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids.
摘要翻译： 衍生自利培酮和由这些免疫原产生的抗体的新型缀合物和免疫原可用于免疫测定用于定量和监测生物液体中的利培酮和帕培酮。
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公开(公告)号：US08450461B2
公开(公告)日：2013-05-28
申请号：US13306278
申请日：2011-11-29
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
CPC分类号： C07K14/001 , C07D471/04 , C07K16/44 , G01N33/94 , Y10S436/815
摘要： Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids.
摘要翻译： 衍生自利培酮和由这些免疫原产生的抗体的新型缀合物和免疫原可用于免疫测定用于定量和监测生物液体中的利培酮和帕培酮。
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公开(公告)号：US08440796B2
公开(公告)日：2013-05-14
申请号：US13303356
申请日：2011-11-23
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
CPC分类号： C07K16/44 , C07D401/04 , C07D401/14 , G01N33/5308 , G01N33/9453 , Y10S436/815
摘要： Novel conjugates and immunogens derived from lenalidomide and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of thalidomide and lenalidomide in biological fluids.
摘要翻译： 衍生自来那度范的新型缀合物和免疫原以及由这些免疫原产生的抗体可用于免疫测定，用于定量和监测生物液体中沙利度胺和来那度胺。
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公开(公告)号：US20120071636A1
公开(公告)日：2012-03-22
申请号：US13306278
申请日：2011-11-29
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Daniel J. Cline , Howard Sard , Vishnumurthy Hegde
IPC分类号： C07K16/44 , C07K14/00 , C07D487/04
CPC分类号： C07K14/001 , C07D471/04 , C07K16/44 , G01N33/94 , Y10S436/815
摘要： Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids.
摘要翻译： 衍生自利培酮和由这些免疫原产生的抗体的新型缀合物和免疫原可用于免疫测定用于定量和监测生物液体中的利培酮和帕培酮。
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公开(公告)号：US20110223611A1
公开(公告)日：2011-09-15
申请号：US12722829
申请日：2010-03-12
申请人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
发明人： Salvatore J. Salamone , Jodi Blake Courtney , Alexander Volkov , Howard Sard , Vishnumurthy Hegde
IPC分类号： G01N33/577 , C07K16/44 , C07K14/765 , C07K14/435 , C07D401/04
CPC分类号： C07K16/44 , C07D401/04 , C07D401/14 , G01N33/5308 , G01N33/9453 , Y10S436/815
摘要： Novel conjugates and immunogens derived from lenalidomide and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of thalidomide and lenalidomide in biological fluids.
摘要翻译： 衍生自来那度范的新型缀合物和免疫原以及由这些免疫原产生的抗体可用于免疫测定，用于定量和监测生物液体中沙利度胺和来那度胺。
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